W. Beau Mitchell - Long Island NY, US Mahmoud Yazdani Abyaneh - Brooklyn NY, US Amanda Chen - Brooklyn NY, US
International Classification:
A61K 31/7105
US Classification:
514 44 A
Abstract:
Disclosed are methods and compositions for preventing and treating conditions associated with platelet aggregation, comprising administering a therapeutically effective amount of a composition that modifies the interaction of DNAJC10 with αIIbβ3 in a megakaryocyte, thereby altering the expression of αIIbβ3 on the surface of the megakaryocyte.
Disclosed are methods and compositions for preventing and treating conditions associated with platelet aggregation, comprising administering a therapeutically effective amount of a composition that modifies the interaction of DNAJC10 with αIIbβ3 in a megakaryocyte, thereby altering the expression of αIIbβ3 on the surface of the megakaryocyte.
CONTRIBUTING: Hadley Hitson of the Montgomery Advertiser and Madeline Mitchell of the Cincinnati Enquirer, members of the USA TODAY Network; and Amanda Chen, Tazbia Fatima, Sara Hutchinson, Tara Garca Mathewson, and Nirvi Shah, The Hechinger Report.