Benjamin Wu

US Patent:

20070093889, Apr 26, 2007

Filed:

Aug 28, 2006

Appl. No.:

11/467847

Inventors:

Benjamin Wu - San Marino CA, US
Fernando Vinuela - Los Angeles CA, US
Yuichi Murayama - Los Angeles CA, US
Yuhuan Xu - Santa Monica CA, US

International Classification:

A61F 2/06

US Classification:

623001380

Abstract:

Non-fragmenting low friction bioactive absorbable coils are disclosed that improve long-term anatomic results in the endovascular treatment of intracranial aneurysms. The coils are composed of at least one biocompatible and bioabsorbable polymer. The coils are then coated with a polymer to reduce the friction. The coating can contain drugs, such as growth factors, and can be used to accelerate histopathologic transformation in aneurysms. The coil can be a polymer such as polyglycolic acid (PGA), poly-L-lactic acid (PLLA), polycaprolactive, poly-L-lactide, polydioxanone, polycarbonates, polyanhydrides, polyglycolic acid/poly-L-lactic acid copolymers, polyhydroxybutyrate/hydroxyvalerate copolymers, or combinations thereof.

US Patent:

20080290554, Nov 27, 2008

Filed:

Mar 31, 2005

Appl. No.:

10/593023

Inventors:

Benjamin M. Wu - Los Angeles CA, US
Michael V. Sofroniew - Los Angeles CA, US
Yuhuan Xu - Los Angeles CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

B29C 44/56

US Classification:

26421112, 4251748 E

Abstract:

Devices for fabricating oriented polymer fibers, and methods for fabricating thereof by electropulling, are provided.

US Patent:

20130069822, Mar 21, 2013

Filed:

Sep 19, 2011

Appl. No.:

13/236575

Inventors:

Benjamin Wu - Yorba Linda CA, US
Stephen R. Peck - West Hills CA, US
Shuwu Wu - Yorba Linda CA, US

International Classification:

G01S 19/41
G01S 19/07
G01S 19/55

US Classification:

34235724, 34235738, 34235744

Abstract:

A differential global positioning system (DGPS) processor can include an almost fixed integer ambiguity (AFIA) module for generating in real-time a multiple dimensional state vector of integer ambiguities and multiple dimensional corrections. The AFIA module can use double difference (DD) measurements for pseudo-range (PR) and carrier phase (CP) pairs generated from at least three global positioning system (GPS) receivers. A DGPS processor can be included in a high data rate real time attitude determination (RTAD) system to achieve high heading accuracy with high integrity.

US Patent:

20130072959, Mar 21, 2013

Filed:

Jul 18, 2012

Appl. No.:

13/552616

Inventors:

Benjamin M. Wu - San Marino CA, US
Fernando Vinuela - Los Angeles CA, US
Yuichi Marayama - Los Angeles CA, US
Yuhuan Xu - Santa Monica CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

A61M 29/00

US Classification:

606200

Abstract:

Non-fragmenting low friction bioactive absorbable coils are disclosed that improve long-term anatomic results in the endovascular treatment of intracranial aneurysms. The coils are composed of at least one biocompatible and bioabsorbable polymer. The coils are then coated with a polymer to reduce the friction. The coating can contain drugs, such as growth factors, and can be used to accelerate histopathologic transformation in aneurysms. The coil can be a polymer such as polyglycolic acid (PGA), poly-L-lactic acid (PLLA), polycaprolactive, poly-L-lactide, polydioxanone, polycarbonates, polyanhydrides, polyglycolic acid/poly-L-lactic acid copolymers, polyhydroxybutyrate/hydroxyvalerate copolymers, or combinations thereof.

US Patent:

20210128791, May 6, 2021

Filed:

Oct 19, 2020

Appl. No.:

17/073945

Inventors:

- Oakland CA, US
Kang Ting - Los Angeles CA, US
Zhong Zheng - Van Nuys CA, US
Benjamin Wu - San Marino CA, US
Yulong Zhang - Los Angeles CA, US

International Classification:

A61L 27/54
A61L 27/04
A61L 27/06
A61L 31/16
A61L 27/08
A61L 31/02
A61N 1/20

Abstract:

The application discloses an implantable device, comprising a galvanic redox system formed on a body substrate of the implantable device. The implantable device has a non-zero surface potential when it is deployed. The galvanic redox system comprises a first metal site and a second metal site, the first metal site comprising a first metal having a first metal electrode potential (FMEP) and the second metal site comprising a second metal having a second metal electrode potential (SMEP), which FMEP being lower than SMEP and SMEP being substantially different such that the implantable device is galvanized when it is deployed. Methods of making and using the implantabe device are also disclosed.

US Patent:

20190275160, Sep 12, 2019

Filed:

Mar 14, 2017

Appl. No.:

16/084525

Inventors:

- Oakland CA, US
Ting Kang - Beverly Hills CA, US
Benjamin M. Wu - San Marino CA, US

International Classification:

A61K 47/54
A61K 47/64
A61K 38/17
A61K 38/18
A61P 19/10
A61K 47/60

Abstract:

The present invention discloses a bone-targeting therapeutic conjugate comprising a formula of TG-M-D (I) or M-D-TG (II) and methods of making and using the same. The present invention also discloses a composition comprising the conjugate and methods of making and using the composition.

US Patent:

20190250156, Aug 15, 2019

Filed:

Jun 7, 2017

Appl. No.:

16/307125

Inventors:

- Oakland CA, US
Benjamin Ming Wu - San Marino CA, US
Daniel William Bradbury - Los Angeles CA, US
Shin Ting Sherine Frieda Cheung - Los Angeles CA, US

International Classification:

G01N 33/543

Abstract:

In various embodiments methods and devices are provided for the detection and/or quantification of an analyte. In certain embodiments a device is provided comprising an aqueous two-phase system (ATPS) comprising a mixed phase solution that separates into a first phase solution and a second phase where, in use, said first phase solution becomes a leading phase and said second phase solution becomes a lagging phase; a lateral-flow assay (LFA); and a probe and/or a development reagent, where in use, said probe associates with said first phase solution in said leading phase of said ATPS and/or said development reagent associates with said second phase solution in said lagging phase of said ATPS. In certain embodiments a “one-pot” system of purifying and amplifying a nucleic acid is provided utilizing, e.g., an ATPS and isothermal amplification reagents.

US Patent:

20190187140, Jun 20, 2019

Filed:

Aug 21, 2017

Appl. No.:

16/326687

Inventors:

- Oakland CA, US
Benjamin Ming Wu - San Marino CA, US
David Yuan Pereira - Los Angeles CA, US
Chloe Michelle Wu - San Marino CA, US
Matthew Foosing Yee - Saratoga CA, US
Joshua Anthony Keefe - Sunnyvale CA, US
Christina Caroline Pearce - Orinda CA, US
Amir Adam Dailamy - Calabasas CA, US
Vincent K. Wong - San Gabriel CA, US
Nguyen Khoi Le - Sacramento CA, US

International Classification:

G01N 33/559
G01N 33/543
G01N 33/545
G01N 33/569
G01N 33/487

Abstract:

It was discovered that hydrogel scaffolds can be used to induce phase separation as aqueous two-phase systems (ATPSs) pass through and/or rehydrate the scaffolds, allowing for concentration of target analyte(s) (e.g., biomolecule(s)) into a particular phase of the ATPS or into a leading front. Accordingly, in various embodiments methods and devices are provided that utilize aqueous two-phase systems and hydrogel scaffolds to improve the sensitivity of assays (e.g., of point-of-care assays) without sacrificing cost or ease of use.