Monoclonal antibodies that bind glypican-2 (GPC2) with high affinity are described. Immunotoxins and chimeric antigen receptors (CARs) that include the disclosed antibodies or antigen-binding fragments thereof are further described. In some instances, the antibody or antigen-binding fragment is humanized. The disclosed GPC2-specific antibodies and conjugates can be used, for example, for the diagnosis or treatment of GPC2-positive cancers, including neuroblastoma, medulloblastoma and retinoblastoma.
JER MANAGEMENT, LLC Real Estate Investment Advisory Services · Investment Advice
7950 Jones Br Dr STE 320, Mc Lean, VA 22107 1650 Tysons Blvd, Mc Lean, VA 22102 27433 Tourney Rd, Santa Clarita, CA 91355 7950 Jones Dr SUITE 320, Mc Lean, VA 22107
Apr 2011 to Present Night AuditorWells Fargo / Wachovia Manassas, VA Aug 2010 to Jun 2011 Bank TellerGeneral Information Services Chapin, SC Mar 2010 to May 2010 Public Records AssociateArmstrong Atlantic State University Savannah, GA May 2008 to Jul 2008 Front Desk Clerk
Education:
Armstrong Atlantic State University Savannah, GA May 2010 Liberal ArtsWindsor Forest High School Savannah, GA May 2007 Diploma
Our Lady of Perpetual Help Catholic School Concordia KS 1968-1971, Lincoln Elementary School Concordia KS 1971-1972, Concordia Middle School Concordia KS 1972-1974, Concordia Junior High School Concordia KS 1974-1976
Brian Esmond will join in Los Angeles from Centerview Partners. Bryan Fleming will be based in New York after leaving Bank of America, where he worked as a managing director in retail and consumer investment banking.