Charles Edwin Carpenter

US Patent:

44736479, Sep 25, 1984

Filed:

Feb 17, 1982

Appl. No.:

6/349691

Inventors:

Charles R. Carpenter - Seguin TX
Robert O. Cone - Seguin TX

Assignee:

AMF Inc. - White Plains NY

International Classification:

C12N 500
C12N 138
A61K 3516
C07G 700

US Classification:

435240

Abstract:

A natural bovine serum-derived serum which has low lipid levels and may additionally have similar globulin and albumin profile as fetal calf serum, as well as controlled levels of hemoglobin, enveloped viruses, steroid hormones, mycoplasma, cholesterol, triglycerides and pesticides, is useful for the promotion of growth of animal and plant cells in tissue culture.

US Patent:

44812981, Nov 6, 1984

Filed:

Feb 19, 1982

Appl. No.:

6/351153

Inventors:

Robert O. Cone - Seguin TX
Charles R. Carpenter - Seguin TX

Assignee:

AMF Incorporated - White Plains NY

International Classification:

G01N 3354
G01N 3378

US Classification:

436500

Abstract:

An immunoassay process for the detection of an antigen in a sample, which comprises: (a) forming a mixture of the sample with (1) a preformed complex of a primary antibody and a secondary binding macromolecule therefor, wherein the primary antibody is present at low concentrations and has substantial specificity for the antigen, the secondary binding macromolecule has substantial affinity for the Fc portion of the primary antibody, and the second binding macromolecule is affinity purified; and with (2) a detectably labeled form of the antigen; (b) incubating the mixture formed in step (a) for a time sufficient to allow the antigen and the detectably labeled antigen to competitively bind to the primary antibody of the preformed complex; (c) detecting the separated complex or the separated suspension medium.

US Patent:

44839227, Nov 20, 1984

Filed:

May 14, 1982

Appl. No.:

6/378441

Inventors:

Charles R. Carpenter - Seguin TX
Robert H. Dodge - New Braunfels TX
Kenneth A. Rosanoff - Seguin TX

Assignee:

AMF Inc. - White Plains NY

International Classification:

C12N 999
C12Q 100
C12Q 144
C12Q 142
C12Q 132

US Classification:

435184

Abstract:

A method for inactivating enzymes, particularly enzymes found in human serum. The method comprises reacting the enzyme in a suitable medium, e. g. human serum, with an inactivating amount of peracetic acid. In the preferred embodiment the treated serum is subsequently neutralized and dialyzed. Preferably, the serums are used as standards for calibration or as a control in assay kits, e. g. RIA, and EIA or enzyme kits, for the determination of specific ligands and enzymes.