Ching-Hua H Tseng

US Patent:

20080117416, May 22, 2008

Filed:

Oct 29, 2007

Appl. No.:

11/927557

Inventors:

Ian W. Hunter - Lincoln MA, US
Shyamal Somaroo - West New York NJ, US
Serge Lafontaine - Lincoln MA, US
Patrick A. Anquetil - Brookline MA, US
Ching-Hua Tseng - Belmont MA, US

International Classification:

G01J 3/44

US Classification:

356301

Abstract:

System and methods are provided to perform non-invasive, real-time, continuous molecular detection and quantification of molecular species in a sample or animal subject using Raman spectroscopy. Such systems and methods may be applied to identify and quantify molecular species found in the body, which may be useful for prenatal diagnosis, detecting deep skin infections, performing cerebral spinal fluid assessment, measuring arterial blood gases, blood glucose, cardiac biomarkers, creatinine flow rates. The non-invasive, quantification of such molecular species continuously in real time enables a significantly more attractive course of therapy than existing protocols.

US Patent:

20080125977, May 29, 2008

Filed:

Oct 29, 2007

Appl. No.:

11/927622

Inventors:

Patrick A. ANQUETIL - Brookline MA, US
Ian W. HUNTER - Lincoln MA, US
Serge LAFONTAINE - Lincoln MA, US
Shyamal SOMAROO - West New York NJ, US
Ching-Hua Tseng - Belmont MA, US

Assignee:

Aretais, Inc. - Lincoln MA

International Classification:

G01N 33/48
G01J 3/44

US Classification:

702 19, 356301

Abstract:

Quantum simulation methods are used to encode the quantum response of a molecular system so as to improve the sensitivity for detection of a target material, while rejecting background. The perturbation and response information may be used to discover the system function of a quantum system, or more generally, of a complex system, such as a physiological system. The approach may be applied to medical non-invasive, real-time, continuous molecular detection and quantification techniques through coherent Raman spectroscopy to enable a significantly more attractive course of therapy than existing protocols.

US Patent:

20120008222, Jan 12, 2012

Filed:

Jul 12, 2011

Appl. No.:

13/180983

Inventors:

Ching-Hua Tseng - Belmont MA, US

International Classification:

G02B 5/08

US Classification:

359839

Abstract:

Provided herein are materials with angle-dependent solar radiation absorptivity, reflectivity, or emissivity. In some embodiments, the material exhibits angle-dependent reflectivity and angle-dependent emissivity. The material can appear as one color or a uniform color to an observer. In some embodiments, the material appears to have different colors from different angles of viewing.

US Patent:

20070129693, Jun 7, 2007

Filed:

Nov 13, 2006

Appl. No.:

11/598556

Inventors:

Ian Hunter - Lincoln MA, US
Andrew Taberner - Lexington MA, US
Dawn Wendell - Farmington CT, US
Nora Hogan - Boston MA, US
Brian Hemond - Lexington MA, US
Ching-Hua Tseng - Belmont MA, US

International Classification:

A61M 35/00

US Classification:

604294000, 604181000

Abstract:

An eye injector for transferring a substance across the surface of the eye of an animal includes a needle-free injector and a patient positioning mechanism. The needle-free injector includes a reservoir for storing the substance to be transferred, a nozzle in fluid communication with the reservoir; and a controllable electromagnetic actuator in communication with the reservoir. The eye injector can also include a targeting light source for directing a beam of light into a pupil of the eye. The needle-free injector can be positioned adjacent to the lens of the eye, therefore producing a jet that intersects with the beam of light at a point in the retina.

US Patent:

20210023293, Jan 28, 2021

Filed:

Oct 2, 2020

Appl. No.:

17/062440

Inventors:

- Newburyport MA, US
Kevin Eggan, JR. - Boston MA, US
Kevin Kalish - Newburyport MA, US
Manuel A. Navia - Lexington MA, US
Kasper Roet - Somerville MA, US
Ching-Hua Tseng - Belmont MA, US
Alan D. Watson - Lexington MA, US
William X. Siopes - Lowell MA, US
Gianna N. Riccardi - South Berwick ME, US
Marcie Ann Glicksman - Salem MA, US

International Classification:

A61M 1/36
A61M 27/00

Abstract:

Cerebrospinal fluid (CSF) and other fluid amelioration systems completely or partially implantable within a mammalian subject and associated methods include a substrate and an agent for amelioration of a toxic biomolecule present in the CSF or fluid, wherein the agent is disposed on or within the substrate.

US Patent:

20170205388, Jul 20, 2017

Filed:

Apr 2, 2015

Appl. No.:

15/301896

Inventors:

- Sugar Land TX, US
John David ROWATT - Harvard MA, US
Francois M. AUZERAIS - Boston MA, US
Simone MUSSO - Cambridge MA, US
Kenneth Kin-nam LIANG - Cambridge MA, US
Harald QUINTUS-BOSZ - Westport CT, US
Joshua P. KINSLEY - Needham MA, US
Alfred J. COSTA - Pepperell MA, US
Ching-Hua TSENG - Belmont MA, US
Julien Prosper Marc AKNIN - Lexington MA, US
Jonathan Andrew BANNISTER - Carlton, AU

International Classification:

G01N 33/38
E21B 41/00
E21B 33/14

Abstract:

Methods and apparatus for analyzing the material properties and behavior of cement as it hydrates under simulated downhole conditions are disclosed. A wellbore cement simulator includes a temperature and pressure controlled innermost oil-filled container; an annulus in contact with the innermost container configured to hold a cement sample; a mesh sleeve in contact with the annulus wherein the mesh sleeve is water permeable to permit hydration of the cement sample; a steel sleeve in contact with the mesh sleeve; an elastomeric bladder surrounding the steel sleeve; and a temperature and pressure controlled outermost oil-filled container.