Choon K Lee

US Patent:

6987154, Jan 17, 2006

Filed:

Feb 19, 2003

Appl. No.:

10/371195

Inventors:

Choon Woo Lee - Pasadena CA, US
Isaac M. Rutenberg - Pasadena CA, US
Robert H. Grubbs - South Pasadena CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

C08F 4/44

US Classification:

526161, 526172, 585511, 585514, 585523, 560205, 562598

Abstract:

This invention relates generally to synthetic procedures that include the step of ring-opening metathesis of cyclic olefins and reaction with an acyclic diene co-reactant to produce regularly repeating A,B-alternating olefin polymers. The A,B-alternating polymers are produced by varying reaction conditions and/or reactant proportions and using only two types of olefin metathesis (ring-opening and cross) to provide regularly repeating ABAB. . . etc. polymers via ring-opening metathesis polymerization (ROMP). More particularly, the invention pertains to synthesis of A,B-alternating olefin polymers via olefin metathesis reactions using a Group 8 transition metal complex as the metathesis catalyst. Polymers provided herein have utility in a variety of fields, including not only polymer chemistry per se, but also in the pharmaceutical, biomedical, and packaging industries where the structure and properties of polymers need to be tightly controlled.

US Patent:

7034096, Apr 25, 2006

Filed:

Feb 19, 2003

Appl. No.:

10/371196

Inventors:

Choon Woo Lee - Pasadena CA, US
Hyunjin M. Kim - San Ramon CA, US
Robert H. Grubbs - South Pasadena CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

C08F 4/44
B01J 31/38

US Classification:

526336, 526171, 526172, 502152, 502155

Abstract:

This invention relates generally to synthetic procedures that include the step of ring-opening metathesis of cyclic olefins and reaction with an acyclic diene co-reactant to produce olefin macrocycles by ring expansion, or alternatively. The ring expansion of the cyclic olefin is provided by three types of sequential olefin metathesis (ring-opening, cross, and ring-closing olefin metathesis). More particularly, the invention pertains to synthesis of olefin macrocycles via olefin metathesis reactions using a Group 8 transition metal complex as the metathesis catalyst. Macrocycles provided herein have a variety of uses in the pharmaceutical, biomedical, organic synthesis and chemical industries, such as the production of crown ethers that are useful as metal complexing species.

US Patent:

7507854, Mar 24, 2009

Filed:

Aug 23, 2004

Appl. No.:

10/924743

Inventors:

Choon Woo Lee - La Canada CA, US
Soon Hyeok Hong - Pasadena CA, US
Daniel P. Sanders - Pasadena CA, US
Robert H. Grubbs - South Pasadena CA, US
Richard L. Pederson - San Gabriel CA, US

Assignee:

Materia, Inc. - Pasadena CA

International Classification:

C07C 69/52

US Classification:

560205

Abstract:

The present invention relates to the use of isomerization inhibitors in olefin metathesis reactions. The inhibitors are low molecular weight organic acids such as formic acid, acetic acid, benzoic acid, and the like.

US Patent:

8067623, Nov 29, 2011

Filed:

Jul 12, 2007

Appl. No.:

11/827937

Inventors:

Choon Woo Lee - La Canada CA, US

Assignee:

Elevance Renewable Sciences, Inc. - Boilingbrook IL

International Classification:

C07C 51/00
C07C 67/00

US Classification:

554124, 560128

Abstract:

This invention relates generally to olefin metathesis, and more particularly relates to the ring-opening, ring insertion cross-metathesis of cyclic olefins with internal olefins such as seed oils and the like. In one embodiment, a method is provided for carrying out a catalytic ring-opening cross-metathesis reaction, comprising contacting at least one olefinic substrate with at least one cyclic olefin as a cross metathesis partner, in the presence of a ruthenium alkylidene olefin metathesis catalyst under conditions effective to allow ring insertion cross metathesis whereby the cyclic olefin is simultaneously opened and inserted into the olefinic substrate. The invention has utility in the fields of catalysis, organic synthesis, and industrial chemistry.

US Patent:

8512722, Aug 20, 2013

Filed:

Jul 23, 2010

Appl. No.:

12/842593

Inventors:

Choon Woo Lee - La Canada CA, US
Robert H. Grubbs - South Pasadena CA, US
Mark Humayun - Glendale CA, US

Assignee:

California Institute of Technology - Pasadena CA
University of Southern California - Los Angeles CA

International Classification:

A01N 25/10

US Classification:

424404, 424 7809, 424 7818, 424 7837, 424405, 424406, 424407, 424409, 424411, 424412, 4284735, 4284744

Abstract:

The disclosure provides methods and materials suitable for preparing coating layers on substrates. The coatings comprise quaternary amine groups and therefore impart anti-bacterial properties to the substrate. In one embodiment, for example, there is provided a quaternary amine-containing polymeric coating comprising propylene and ethylene repeat units.

US Patent:

20210130270, May 6, 2021

Filed:

Jan 14, 2021

Appl. No.:

17/149662

Inventors:

- Santa Monica CA, US
Choon Woo LEE - Santa Monica CA, US
David ROZZELL - Burbank CA, US

Assignee:

Provivi, Inc. - Santa Monica CA

International Classification:

C07C 29/36
C07C 67/343
C07C 51/09
C07C 67/293
C07C 253/30
C07C 45/44

Abstract:

Methods for the preparation of alkenes including insect pheromones are described. The methods include homologation reactions employing reagents such as 1,3-diesters, epoxides, cyanoacetates, and cyanide salts for elongation of starting materials and intermediates by one or two carbon atoms. The alkenes include insect pheromones useful in a number of agricultural applications.

US Patent:

20180362714, Dec 20, 2018

Filed:

May 22, 2018

Appl. No.:

15/985966

Inventors:

- Pasadena CA, US
Choon Woo LEE - La Canada CA, US

International Classification:

C08G 73/02
C09D 179/02

Abstract:

The disclosure provides methods and materials suitable for preparing coating layers on substrates. The coatings comprise quaternary amine groups and therefore impart anti-bacterial properties to the substrate. In one embodiment, for example, there is provided a quaternary amine-containing polymeric coating comprising propylene and ethylene repeat units.