Christopher A Bidwell

US Patent:

20020127642, Sep 12, 2002

Filed:

Aug 20, 2001

Appl. No.:

09/932888

Inventors:

Michael Spurlock - Lafayette IN, US
Christopher Bidwell - West Lafayette IN, US

International Classification:

C12P021/02
C12N005/06
C07H021/04
C12N009/16
C07K014/435

US Classification:

435/069100, 435/325000, 435/320100, 530/350000, 435/196000, 536/023500

Abstract:

A porcine adipocyte-specific polypeptide, termed leptin, is expressed in the fat tissue of pigs. Expression may be altered in over fat pigs, or expression may be in the form of a protein of lesser biological activity relative to that of leaner pigs. The porcine adipocyte polypeptide, DNA and RNA molecules coding therefor, methods for its preparation, and antibodies specific for the polypeptide are disclosed. Methods for determining the susceptibility of a pig to fat deposition are based on measuring the levels of the porcine adipocyte polypeptide in a biological fluid or tissue extract or by measuring mRNA encoding the porcine adipocyte polypeptide in cells of the subject. Methods of evaluating an agent related to the deposition of fat in swine comprise contacting the agent with an adipocyte in vitro and measuring the amount of the porcine adipocyte polypeptide or mRNA that is produced by the adipocyte. Methods of limiting fat deposition include administering porcine leptin or porcine leptin DNA, and methods of regulating intake include administering porcine leptin, porcine leptin DNA, or an antibody directed against porcine leptin.

US Patent:

46975462, Oct 6, 1987

Filed:

May 30, 1986

Appl. No.:

6/868734

Inventors:

Charles L. Chrisman - West Lafayette IN
Christopher A. Bidwell - Davis CA
George S Libey - Lafayette IN

Assignee:

Purdue Research Foundation - West Lafayette IN

International Classification:

A01K 6100

US Classification:

119 3

Abstract:

A method for the induction of tetraploidy in channel catfish by heat-shocking fertilized eggs is described. Fertilized catfish eggs are treated after a preliminary incubation period and prior to first cell division cleavage by immersing the fertilized eggs in water at a temperature of about 40. degree. C. to about 43. degree. C. for a temperature-dependent period of time ranging from about 1 to about 4 minutes. Incubation of the heat-shocked eggs allows maturation to tetraploid catfish fry. Breeding of tetraploid catfish with normal diploids produces rapid growing triploid offspring.

US Patent:

62775928, Aug 21, 2001

Filed:

Jul 31, 1996

Appl. No.:

8/692922

Inventors:

Christopher A. Bidwell - West Lafayette IN
Michael E. Spurlock - Pacific MO

Assignee:

Purina Mills, Inc. - St. Louis MO
Purdue Research Foundation - West Lafayette IN

International Classification:

C07K 14435
C12N 1512
C12N 1563
C12N 121

US Classification:

435 691

Abstract:

A porcine adipocyte-specific polypeptide, termed leptin, is expressed in the fat tissue of pigs. Expression may be altered in over fat pigs, or expression may be in the form of a protein of lesser biological activity relative to that of leaner pigs. The porcine adipocyte polypeptide, DNA and RNA molecules coding therefor, methods for its preparation, and antibodies specific for the polypeptide are disclosed. Methods for determining the susceptibility of a pig to fat deposition are based on measuring the levels of the porcine adipocyte polypeptide in a biological fluid or tissue extract or by measuring mRNA encoding the porcine adipocyte polypeptide in cells of the subject. Methods of evaluating an agent related to the deposition of fat in swine comprise contacting the agent with an adipocyte in vitro and measuring the amount of the porcine adipocyte polypeptide or mRNA that is produced by the adipocyte. Methods of limiting fat deposition include administering porcine leptin or porcine leptin DNA, and methods of regulating intake include administering porcine leptin, porcine leptin DNA, or an antibody directed against porcine leptin.

US Patent:

54490898, Sep 12, 1995

Filed:

Feb 2, 1994

Appl. No.:

8/190277

Inventors:

Donald R. Turner - Shelbyville IN
Ronald L. Kennedy - Fishers IN
Christopher C. Bidwell - Dunwoody GA
Bruce A. Williams - Shelbyville IN

Assignee:

Williams Industries, Inc. - Shelbyville IN

International Classification:

B65D 142

US Classification:

220675

Abstract:

A plastic bell fountain cup includes a bottom surface, and a side wall formed integrally with and extending upwardly from the bottom surface. The side wall has a lower portion adjacent the bottom surface, an upper lip portion defining a top opening of the cup, and a radially outwardly expanded portion located between the lower portion and the upper lip portion. The radially outwardly expanded portion has a maximum diameter larger than a diameter of the bottom surface and larger than a diameter of the top opening. The side wall has a substantially uniform thickness throughout the lower portion, the radially outwardly expanded portion, and at least a part of the upper lip portion.