Chunming Liu from 3217 Malone Dr, Lexington, KY 40513, age 59

Name / Title

Company / Classification

Phones & Addresses

Chunming Liu
Director

BIOMEDLAB, INC

99 Florence St ROOM 209, Malden, MA 02148

License #:

4301087066 - Active

Category:

Medicine

Issued Date:

Dec 14, 2005

Expiration Date:

Jan 31, 2019

Type:

Medical Doctor

Stilbene Analogs And Methods Of Treating Cancer
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US Patent:

20120196874, Aug 2, 2012
Filed:

Jan 27, 2012
Appl. No.:

13/360109
Inventors:

David WATT - Lexington KY, US
Chunming Liu - Lexington KY, US
Wen Zhang - Lexington KY, US
International Classification:

A61K 31/05
C07C 43/23
A61K 31/09
C07C 291/04
A61K 31/136
C07C 211/52
C07D 495/04
A61K 31/4188
C07D 295/073
A61K 31/495
C07D 233/64
A61K 31/4164
A61P 35/00
G01N 33/53
G01N 33/566
C12Q 1/68
C07C 39/21
US Classification:

51425503, 568729, 514733, 568646, 514720, 564300, 514645, 564442, 514646, 5483041, 514387, 544395, 5483461, 514396, 436 86, 436501, 435 611
Abstract:

Stilbene analogs and pharmaceutical compositions that are useful for the treatment of various cancers, including without limitation, colorectal cancer (CRC) and breast cancer are disclosed. The halogenated stilbene analogs include nitrogen heteroaryl groups and/or amino groups on the stilbene ring.

Semisynthetic Aurones And Methods Of Use Thereof
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US Patent:

20200354348, Nov 12, 2020
Filed:

Jan 18, 2019
Appl. No.:

16/963759
Inventors:

- Lexington KY, US
Chunming Liu - Lexington KY, US
Yanqi Xie - Lexington KY, US
David S. Watt - Lexington KY, US
International Classification:

C07D 405/10
A61P 35/00
C07D 413/10
C07D 417/10
C07D 307/83
C07D 405/06
Abstract:

Provided herein are semisynthetic aurones, pharmaceutical compositions, and methods of treating cancer. The semisynthetic aurone compound including a structure according to Formula (I) or pharmaceutically acceptable salt thereof, where Ris H, an alkyl cyano, an alkyl phenyl substituted with one or more halogens, or any combination thereof, and Ris an aromatic group, a heterocycle, or a combination thereof. The pharmaceutical composition includes the semisynthetic aurone compound and a carrier. The method includes administering to a patient in need of such treatment an effective amount of the semisynthetic aurone compound.

Phenylethynyl-Substituted Benzenes And Heterocycles For The Treatment Of Cancer
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US Patent:

20180369222, Dec 27, 2018
Filed:

May 10, 2018
Appl. No.:

15/976643
Inventors:

- Lexington KY, US
Chunming LIU - Lexington KY, US
Wen ZHANG - Lexington KY, US
Markos LEGGAS - Lexington KY, US
International Classification:

A61K 31/45
A61K 31/5375
A61K 31/495
A61K 31/40
A61K 31/4418
A61K 31/4439
A61K 31/4965
A61K 31/404
A61K 31/416
A61K 31/437
A61K 31/47
A61K 31/4706
A61K 31/472
A61K 31/4725
A61P 35/00
Abstract:

Halogenated phenylethynyl-substituted heterocycles that possess either an N-alkylamino or N,N-dialkylarnino group attached to the heterocycle or halogenated phenylethynyl-substituted benzenes that a nitrogen-containing heterocycle attached to the benzene inhibit the proliferation cancer cells and are useful antineoplastic agents.

Arylquinoline, Arylquinolone And Arylthioquinolone Derivatives And Use Thereof To Treat Cancer
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US Patent:

20160332971, Nov 17, 2016
Filed:

May 11, 2016
Appl. No.:

15/152185
Inventors:

- Lexington KY, US
Chunming LIU - Lexington KY, US
Vivek M. RANGNEKAR - Lexington KY, US
Ravshan BURIKHANOV - Lexington KY, US
Wen ZHANG - Lexington KY, US
International Classification:

C07D 215/38
C07D 215/48
G01N 33/50
C07D 471/04
Abstract:

Arylquinoline derivatives and their use for treating cancer or cancer metastasis is disclosed. The compounds of the subject technology promote cells to secrete a pro-apoptotic tumor suppressor, i.e., prostate apoptosis response-4 (Par-4), which in turn promote apoptosis in cancer cells or metastatic cells.

3-Aryl-4H-Chromene-4-Ones As Antineoplastic Agents For The Treatment Of Cancer
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US Patent:

20160332981, Nov 17, 2016
Filed:

May 9, 2016
Appl. No.:

15/149940
Inventors:

- Lexington KY, US
Mykhaylo S. FRASINYUK - Kyiv, UA
Chunming LIU - Lexington KY, US
David S. WATT - Lexington KY, US
International Classification:

C07D 311/30
C07D 405/04
C07D 493/04
C07D 407/04
C07D 493/14
Abstract:

Isoflavonoids or pharmaceutically acceptable salts thereof or pharmaceutically acceptable compositions thereof for the treatment of prostate cancer or for the treatment or inhibition of prostate cancer metastasis in a patient in need thereof are disclosed.

Arylquinoline And Analog Compounds And Use Thereof To Treat Cancer
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US Patent:

20160280652, Sep 29, 2016
Filed:

Nov 21, 2014
Appl. No.:

15/036916
Inventors:

- Lexington KY, US
Chunming LIU - Lexington KY, US
Vivek RANGNEKAR - Nicholasville KY, US
Ravshan BURIKHANOV - Lexington KY, US
Wen ZHANG - Lexington KY, US
International Classification:

C07D 215/38
C07D 215/36
C07D 215/06
C07D 215/227
Abstract:

The subject technology relates to arylquinoline compounds and their use for treating cancer or cancer metastasis. The compounds of the subject technology promote cells to secrete a pro-apoptotic tumor suppressor, i.e., prostate apoptosis response-4 (Par-4), which in turn promote apoptosis in cancer cells or metastatic cells.

Halogenated Diarylacetylenes And Methods Of Treating Cancer
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US Patent:

20150272908, Oct 1, 2015
Filed:

Mar 25, 2015
Appl. No.:

14/668865
Inventors:

- Lexington KY, US
Wen ZHANG - Lexington KY, US
Chunming LIU - Lexington KY, US
David WATT - Lexington KY, US
International Classification:

A61K 31/136
Abstract:

Halogenated diarylacetylenes, e.g., diarylacetylenes having at least one halo substituent in one aryl ring and an amine in the opposing aryl ring, can inhibit the proliferation of LS174T colon cancer cells through the inhibition of c-myc and induction of the cyclin-dependent kinase inhibitor-1 (i.e., p21(Wif1/Cip1)). Such compounds are useful as antineoplastic agents.

Stilbene Analogs And Methods Of Treating Cancer
view source
US Patent:

20140249161, Sep 4, 2014
Filed:

Feb 27, 2014
Appl. No.:

14/192616
Inventors:

- Lexington KY, US
Chunming LIU - Lexington KY, US
Wen ZHANG - Lexington KY, US
Assignee:

UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION - Lexington KY
International Classification:

C07C 39/21
C07C 291/04
C07D 295/073
C07D 495/04
C07D 233/64
C07C 43/23
C07C 211/52
US Classification:

51425503, 568729, 514733, 568646, 514720, 564300, 514645, 564442, 514646, 5483041, 514387, 5483461, 514396, 544395
Abstract:

Stilbene analogs and pharmaceutical compositions that are useful for the treatment of various cancers, including without limitation, colorectal cancer (CRC) and breast cancer are disclosed. The halogenated stilbene analogs include nitrogen heteroaryl groups and/or amino groups on the stilbene ring.