William J. Havel - Maple Grove MN Joe D. Bourland - West Lafayette IN Leslie A. Geddes - Lafayette IN Willis A. Tacker - Lafayette IN Darrell O. Wagner - Isanti MN
Assignee:
Purdue Research Foundation - West Lafayette IN
International Classification:
A61N 136
US Classification:
607 7, 607 8
Abstract:
A controlled-power defibrillator and method of defibrillation for automatically compensating for changes in patient resistance during delivery of a defibrillation pulse. A switching power converter is connected between a storage capacitor and a pair of electrodes adapted for connection to a patients body, either internally or externally. A closed-loop power control circuit is operatively connected to the power converter for control of the power delivered to the patient, the power control circuit generating a target voltage signal for the storage capacitor, the target voltage signal having a defined relationship with the waveform of the power desired to be delivered to the patient. The power control circuit monitors the actual voltage on the storage capacitor and adjusts the delivery of power to the patient as a function of the difference between desired and actual storage capacitor voltage. The power converter is adapted to capture energy from the discharge of an existing defibrillator and to convert captured energy from the existing defibrillator to a waveform different from that generated by the existing defibrillator.
Expandable Fixation Elements For Subcutaneous Electrodes
Ron Heil - Roseville MN, US Darrell Orvin Wagner - Isanti MN, US Adam W. Cates - Minneapolis MN, US Curtis Charles Lindstrom - Roseville MN, US
Assignee:
Cardiac Pacemakers, Inc. - St. Paul MN
International Classification:
A61N 1/05
US Classification:
607116
Abstract:
Subcutaneous systems and leads may be fixed in tissue after placement by use of one or more expanding fixation elements. An expanding fixation element is provided on an implantable lead and configured to secure one or both of a subcutaneous electrode and the lead body within subcutaneous non-intrathoracic tissue. A delivery apparatus comprising a sheath may be included that is configured to introduce the lead to a desired subcutaneous non-intrathoracic location within the patient. A method of lead delivery typically involves introducing a sheath into a subcutaneous non-intrathoracic body location of a patient, providing a lead comprising a lead body and an electrode, and advancing the lead through the sheath and to the subcutaneous non-intrathoracic body location. The method further involves fixing the lead to subcutaneous non-intrathoracic tissue using an expanding fixation element and thereafter removing the sheath from the patient.
Paul Haefner - Circle Pines MN, US Darrell Orvin Wagner - Isanti MN, US Jason Alan Shiroff - Shoreview MN, US Marina Brockway - Shoreview MN, US Apurv Kamath - Solana Beach CA, US
Assignee:
Cardiac Pacemakers, Inc. - St. Paul MN
International Classification:
A61B 5/04 A61N 1/08 A61N 1/37
US Classification:
607 27, 607 62, 600509
Abstract:
Implementing a subcutaneous medical electrode system involves positioning a number of electrode subsystems in relation to a heart so that noise cancellation provides an improved signal to noise ratio of the cardiac signal and/or to provide one electrode arrangement preferential for cardiac signals and another arrangement preferential for noise signals. One of the electrode subsystems so positioned may include one or more can electrodes located on a housing enclosing a medical device. The medical device may be configured to provide therapeutic, diagnostic, or monitoring functions, including, for example, cardiac arrhythmia therapy.
Subcutaneous Electrode And Lead With Temporary Pharmacological Agents
Adam W. Cates - Minneapolis MN, US Darrell Orvin Wagner - Isanti MN, US Curtis Charles Lindstrom - Roseville MN, US Ron Heil - Roseville MN, US
Assignee:
Cardiac Pacemakers, Inc. - St. Paul MN
International Classification:
A61N 1/08
US Classification:
607120
Abstract:
An implantable subcutaneous device and method employ a lead and an electrode for cardiac monitoring and intervention. The device includes an implantable lead having a lead body, a subcutaneous electrode coupled to the lead body, and a pharmacological agent provided on the implantable lead and/or electrode. The pharmacological agent provides a temporary therapeutic treatment to subcutaneous non-intrathoracic tissue. A method of implanting subcutaneous leads involves providing a lead including a lead body, a subcutaneous electrode, and a pharmacological agent, and delivering the pharmacological agent to subcutaneous non-intrathoracic tissue surrounding the lead.
Subcutaneous Cardiac Rhythm Management With Asystole Prevention Therapy
Eric G. Lovett - Roseville MN, US Adam W. Cates - Minneapolis MN, US Darrell Orvin Wagner - Isanti MN, US Mike Favet - San Jose CA, US Apurv Kamath - Solana Beach CA, US
Assignee:
Cardiac Pacemakers, Inc. - St. Paul MN
International Classification:
A61N 1/362
US Classification:
607 14, 67 4, 67 10, 67 63
Abstract:
Systems and methods provide for sensing of cardiac activity from a subcutaneous, non-intrathoracic location, and detecting a cardiac condition necessitating treatment in response to the sensed cardiac activity. One of a number of cardiac therapies may be selectively delivered to treat the detected cardiac condition, such cardiac therapies including at least a tachycardia therapy, a bradycardia therapy, and an asystole prevention therapy.
Subcutaneous Electrode And Lead With Phoresis Based Pharmacological Agent Delivery
Ron Heil - Roseville MN, US Paul A. Haefner - Circle Pines MN, US Adam W. Cates - Minneapolis MN, US Darrell Orvin Wagner - Isanti MN, US Curtis Charles Lindstrom - Roseville MN, US
Assignee:
Cardiac Pacemakers, Inc. - St. Paul MN
International Classification:
A61N 1/05
US Classification:
607120, 607 3
Abstract:
An implantable subcutaneous device includes a lead and electrode for cardiac monitoring and intervention. The device has an implantable lead including a lead body, a subcutaneous electrode supported by the lead body and a pharmacological agent impelled from the device using phoresis. The pharmacological agent provides a therapeutic treatment to subcutaneous non-intrathoracic tissue. A method of implanting subcutaneous leads involves providing a lead including a lead body, a subcutaneous electrode, and a pharmacological agent and using phoresis to impel the pharmacological agent into subcutaneous non-intrathoracic tissue surrounding the lead.
Method And Apparatus For Tissue Protection Against Ischemia Using Remote Conditioning
Haris J. Sih - Minneapolis MN, US Tamara Colette Baynham - Blaine MN, US Darrell O. Wagner - Isanti MN, US
Assignee:
Cardiac Pacemakers, Inc. - St. Paul MN
International Classification:
A61N 1/372
US Classification:
607 3
Abstract:
A stimulation system delivers stimulation to protect an ischemic region of a body from tissue damage caused by ischemia. The stimulation is delivered to one or more stimulation sites remote from the ischemic region to elicit a physiological effect that protects the ischemic region from the tissue damage caused by ischemia. In one embodiment, the stimulation system delivers cardioprotective stimulation to one or more stimulation sites remote from the heart to protect the heart from injuries associated with cardiac ischemic events. In another embodiment, the stimulation system delivers remote conditioning stimulation to one or more stimulation sites in or on the heart to protect a non-cardiac region from injuries associated with non-cardiac ischemic events.
Methods To Position Therapeutic Agents Using A Magnetic Field
Haris J. Sih - Minneapolis MN, US Craig Stolen - New Brighton MN, US Jihong Ou - Maple Grove MN, US Darrell O. Wagner - Isanti MN, US
Assignee:
Cardiac Pacemakers, Inc. - St. Paul MN
International Classification:
A61N 2/00
US Classification:
600 12, 600 11, 128899
Abstract:
A system for controlling the location of a therapeutic agent administered to a mammal is provided. The system employs a device that is capable of generating a magnetic field and a therapeutic agent labeled with a magnetically responsive moiety. Methods which employ the device and the therapeutic agent are also provided.
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