Group Health Cooperative since Aug 2011
Grant Manager
Group Health Cooperative Sep 2008 - Aug 2011
Senior Financial Analyst
Robert Half Management Resources Feb 2008 - Aug 2008
Consultant
Church Pension Group Feb 2003 - Jan 2008
Sr. Financial/Operations Analyst
NADAP Inc Aug 2000 - Feb 2003
Accounting Manager
Education:
Saint John's University - Peter J. Tobin College of Business 1987 - 1991
Bachelor of Science (BS), Finance, General
There is disclosed cDNA sequences and polypeptides having the enzyme CDP-diacylglycerol synthase (CDS) activity. CDS is also known as CTP:phosphatidate cytidylyltransferase. There is further disclosed methods for isolation and production of polypeptides involved in phosphatidic acid metabolism and signaling in mammalian cells, in particular, the production of purified forms of CDS.
Method Of Screening Compounds That Inhibit Lysophosphatidic Acid Acyltransferase
David W. Leung - Mercer Island WA David Hollenback - Seattle WA
Assignee:
Cell Therapeutics, Inc. - Seattle WA
International Classification:
C12Q 148
US Classification:
435 15, 435193
Abstract:
Polypeptides are obtained, for example, via expression of encoding cDNA sequences, that have the activity of the enzyme lysophosphatidic acid acyltransferase (LPAAT), also known as 1-acyl sn-glycerol-3-phosphate acyltransferase.
Human Lysophosphatidic Acid Acyltransferase Gamma-2 Polypeptide
David W. Leung - Mercer Island WA, US David Hollenback - Seattle WA, US
Assignee:
Cell Therapeutics Inc. - Seattle WA
International Classification:
C12N 9/10
US Classification:
435193
Abstract:
Polypeptides are obtained, for example, via expression of encoding cDNA sequences, that have the activity of the enzyme lysophosphatidic acid acyltransferase (LPAAT), also known as 1-acyl sn-glycerol-3-phosphate acyltransferase.
Human Lysophoshatidic Acid Acyltransferase Gamma-1 Polypeptide
David W. Leung - Mercer Island WA, US David Hollenback - Seattle WA, US
Assignee:
Cell Therapeutics Inc. - Seattle WA
International Classification:
G12N 9/10
US Classification:
435193
Abstract:
Polypeptides are obtained, for example, via expression of encoding cDNA sequences, that have the activity of the enzyme lysophosphatidic acid acyltransferase (LPAAT), also known as 1-acyl sn-glycerol-3-phosphate acyltransferase.
Baoqing Gong - Shoreline WA, US John Tulinsky - Seattle WA, US Lynn Bonham - Seattle WA, US J. Peter Klein - Vashon WA, US Robert E. Finney - Shoreline WA, US David M. Hollenback - Seattle WA, US Scott A. Shaffer - Seattle WA, US Norina M. Tang - Ann Arbor MI, US Thayer H. White - Bellevue WA, US David W. Leung - Mercer Island WA, US
Assignee:
Cell Therapeutics, Inc. - Seattle WA
International Classification:
A01N 43/66
US Classification:
514241, 544196, 544198, 544204, 544207, 544215
Abstract:
The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.
This invention relates to a biotechnology invention concerning human phosphatidic acid phosphatase. More particularly, this invention relates to three variants of human phosphatidic acid phosphatase namely PAP-α(1 and 2), PAP-β and PAP-γ and uses thereof.
Lynn Bonham - Seattle WA, US Baoqing Gong - Shoreline WA, US Robert E Finney - Shoreline WA, US David M Hollenback - Seattle WA, US J. Peter Klein - Vashon WA, US David W Leung - Mercer Island WA, US Scott A Shaffer - Seattle WA, US Norina M Tang - Ann Arbor MI, US John Tulinsky - Seattle WA, US Thayer H White - Bellevue WA, US
Assignee:
Cell Therapuetics, Inc. - Seattle WA
International Classification:
C07D 251/52 C07D 251/38 A61K 31/53 A61P 35/00
US Classification:
544206, 544208, 544213, 514241
Abstract:
The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.
Lynn Bonham - Seattle WA, US Baoqing Gong - Shoreline WA, US Robert E Finney - Shoreline WA, US David M Hollenback - Seattle WA, US J Peter Klein - Vashon WA, US David W Leung - Mercer Island WA, US Scott A Shaffer - Seattle WA, US Norina M Tang - Ann Arbor MI, US John Tulinsky - Seattle WA, US Thayer H White - Bellevue WA, US
The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.
Sir James Douglas Elementary School Vancouver Saudi Arabia 1987-1991, Talmey Elementary School Richmond Saudi Arabia 1992-1994, Cambie High School Richmond Saudi Arabia 1995-2000
Community:
Jamie Amos, Ernie Kilroe, Barbara Moxin, Don Crabbe
Unless they're like David Leung in Hong Kong who'll sleep through the opening ceremony at its 4 a.m. local start time, fans will stay up in the middle of the night and, bleary-eyed, call in sick from work the next day. Others will stream the broadcasts in their office cubicle, in between work e-mail