Peter A. Cohen - Bethesda MD Brian J. Czerniecki - Haddenfield NJ Gary K. Koski - Bethesda MD David E. Weng - Bethesda MD Charles Carter - Gaithersberg MD John O. Ojeifo - Washington DC Gretchen N. Schwartz - Wheaton MD
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
C12N 508
US Classification:
435326, 435 724, 435372, 435383
Abstract:
The present invention relates to methods of increasing the antigen presenting ability of leukemia cells by contacting them with an agent which increases the intracellular calcium level. Methods of treating leukemia are also disclosed.
Method For Inducing Monocytes To Exhibit The Phenotype Of Activated Myeloid Dendritic Cells
Peter A. Cohen - Bethesda MD Brian J. Czerniecki - Haddenfield NJ Gary K. Koski - Bethesda MD David E. Weng - Bethesda MD Charles Carter - Gaithersberg MD John O. Ojeifo - Washington DC Gretchen N. Schwartz - Wheaton MD
Assignee:
The United States of America as represented by the Department of Health & Human Services - Washington DC
International Classification:
C12N 508
US Classification:
435372
Abstract:
The present invention relates to methods of increasing the antigen presenting ability of monocytes by contacting them with an agent which increases the intracellular calcium level. Methods of obtaining the monocytes are also disclosed. In addition, the present invention relates to methods of inducing bone marrow progenitor cells and endothelial cells to express molecules involved in generating immune responses. Methods of modulating the expression of molecules involved in generating immune responses are also disclosed, as are methods of treating cancer and leukemia.
- West Midlands, GB - Buffalo NY, US Mark McKinlay - Phoenixville PA, US Hans Minderman - Buffalo NY, US Yasuhiro Mitsuuchi - Phoenixville PA, US David Weng - Chevy Chase MD, US
Assignee:
Health Researc Inc. - Buffalo NY
International Classification:
G01N 33/574 G06Q 30/02 A61K 38/05
Abstract:
A method of diagnosing and treating proliferative disorders in connection with the use of a Smac mimetic.
Medicine Doctors
Dr. David E Weng, Chevy Chase MD - MD (Doctor of Medicine)
9017 Spring Hill Ln Suite L, Chevy Chase, MD 20815 (301)3985879 (Phone), (866)8581893 (Fax)
Certifications:
Internal Medicine, 1995 Medical Oncology, 2008
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School Johns Hopkins University / School of Medicine Graduated: 1992 Medical School The Johns Hopkins Hospital Graduated: 1992 Medical School Natl Cancer Inst Graduated: 1992
Anne Arundel Medical Center Geaton & JoAnn DeCesaris Cancer Institute 2001 Medical Pkwy, Annapolis, MD 21401 (800)9662619 (phone)
Anne Arundel Medical Center Hematology & Oncology 1106 Annapolis Rd STE 210, Odenton, MD 21113 (443)4814884 (phone), (410)5735305 (fax)
Education:
Medical School Johns Hopkins University School of Medicine Graduated: 1992
Conditions:
Hemolytic Anemia Malignant Neoplasm of Female Breast Non-Hodgkin's Lymphoma Anemia Breast Neoplasm, Malignant
Languages:
English
Description:
Dr. Weng graduated from the Johns Hopkins University School of Medicine in 1992. He works in Odenton, MD and 1 other location and specializes in Hematology/Oncology.
There are upward of 60 subtypes of non-Hodgkin lymphoma, said Dr. David Weng, a staff oncologist at Anne Arundel Medical Center. The kind that Hogan has, and Banusiewicz had, B-cell lymphoma, is among the most common. For aggressive lymphomas, chemotherapy is the most effective treatment.