Eric A May

US Patent:

20100057816, Mar 4, 2010

Filed:

Aug 25, 2009

Appl. No.:

12/547389

Inventors:

Eric May - Boulder CO, US

International Classification:

G06F 7/00

US Classification:

707800, 707E17044

Abstract:

This is a method of visually organizing research including: progress, history, decisions, notes and results. This method automatically records the details of a research project as it is happening and intuitively allows the user and/or users to add their own information in the process. Organization may be both automatically and manually conducted. The user's research may be displayed in multiple visual layouts allowing for quick review, organization and accessibility to other users.

US Patent:

20100058159, Mar 4, 2010

Filed:

Aug 25, 2009

Appl. No.:

12/547436

Inventors:

Eric May - Boulder CO, US

International Classification:

G06F 3/14

US Classification:

715200

Abstract:

This is a method of automatically tracking and displaying “Search Histories” inline within the context of an Internet research project. Links to context specific history listings can be displayed contextually within a block diagram and/or within a list. This contextual view of histories facilitates finding and quickly returning to a previously visited web pages. The detailed information about these pages contained in the history pages further facilitates finding the web page of interest. These tools are particularly helpful in the context of an Internet research project.

US Patent:

20120122094, May 17, 2012

Filed:

Feb 1, 2011

Appl. No.:

13/382509

Inventors:

Eric May - Chandler AZ, US
Alexandra Nagy - Oro Valley AZ, US
Jerome Kosmeder - Tucson AZ, US

International Classification:

G01N 21/64
C12Q 1/68
B82Y 15/00

US Classification:

435 611, 436501, 977774, 977902

Abstract:

Embodiments of a composition for stabilizing fluorescent signal of nanoparticles and methods for its use are disclosed. In some embodiments, the composition has a pH from 7 to 10 and includes borate, protein and/or protein hydrolysate, an amine, a preservative, and a nonionic surfactant. In particular embodiments, the amine is an N-ethanol substituted amine, such as ethanolamine, diethanolamine, triethanolamine, N-methyldiethanolamine, N,N-dimethylethanolamine, or a combination thereof. In some embodiments, a fluorescent particle solution, such as a quantum dot solution or quantum dot conjugate solution, is diluted in the composition and stored at 4 C. In certain embodiments, the fluorescence intensity of the diluted fluorescent particle remains substantially the same when stored at 4 C. for at least one month or at least three months. In particular embodiments, a diluted quantum dot conjugate is used to detect a hybridized probe or a protein antigen.

US Patent:

20120171668, Jul 5, 2012

Filed:

Dec 28, 2011

Appl. No.:

13/339066

Inventors:

Eric J. May - Chandler AZ, US
Adrian E. Murillo - Tucson AZ, US
Jerome W. Kosmeder - Tucson AZ, US

International Classification:

C12Q 1/68
G01N 33/536

US Classification:

435 61, 435 79

Abstract:

This disclosure relates to compositions that enhance the deposition of detectable moieties on tissue samples, methods utilizing these compositions and kits including these compositions. The compositions include a deposition enhancer having a formulawhere R, R, R, and Rare independently selected from aliphatic, aryl, halogen, a heteroatom-containing moiety, and hydrogen; Rand/or Rcan be bound to Rto form a fused, aromatic ring system; Ris selected from a heteroatom-containing moiety; A is selected from, a carbon atom, a heteroatom, other than sulfur, and any combination thereof; n is 1-5, an enzyme, a specific binding moiety and a detectable moiety.

US Patent:

20130109019, May 2, 2013

Filed:

Jul 1, 2011

Appl. No.:

13/805978

Inventors:

Adrian E. Murillo - Tucson AZ, US
Jerome W. Kosmeder - Tucson AZ, US
Eric May - Chandler AZ, US
William Day - Tucson AZ, US
Mark Lefever - Oro Valley AZ, US
Anne M. Pedata - Tucson AZ, US
Christopher Bieniarz - Tucson AZ, US
Phillip Miller - Tucson AZ, US

International Classification:

C07D 277/54
C07C 237/20
C07D 271/12
C07D 233/90
C07D 243/00
C07D 241/52

US Classification:

435 611, 540517, 544355, 548126, 548185, 5483275, 564155, 435 28, 435 71, 435 79

Abstract:

Embodiments of hapten conjugates including a hapten, an optional linker, and a peroxidase-activatable aryl moiety are disclosed. In some embodiments, the peroxidase-activatable aryl moiety is tyramine or a tyramine derivative. Embodiments of methods for making and using the hapten conjugates also are disclosed. In particular embodiments, the hapten conjugates are used in a signal amplification assay. In certain embodiments, the hapten is an oxazole, a pyrazole, a thiazole, a benzofurazan, a triterpene, a urea, a thiourea other than a rhodamine thiourea, a nitroaryl other than dinitrophenyl or trinitrophenyl, a rotenoid, a cyclolignan, a heterobiaryl, an azoaryl, a benzodiazepine, or 7-diethylamino-3-carboxycoumarin. The hapten is coupled to the peroxidase-activatable aryl moiety directly or indirectly via a linker. In certain embodiments, the hapten conjugates are used in multiplexed assays.

US Patent:

20200348215, Nov 5, 2020

Filed:

Jul 20, 2020

Appl. No.:

16/933658

Inventors:

- Tucson AZ, US
Brian D. Kelly - Tucson AZ, US
Eric J. May - Chandler AZ, US
Larry Morrison - Oro Valley AZ, US

International Classification:

G01N 1/30
C12Q 1/28
G01N 33/532
G01N 33/535
G01N 33/543
G01N 33/58

Abstract:

Disclosed embodiments concern a composition comprising DAB chromogen, and/or derivative thereof, a stabilizer, and polymer capable of preventing or reducing DAB precipitation relative to a composition that does not comprise the polymer. Also disclosed herein is a method for using the disclosed composition and embodiments of a kit.

US Patent:

20170212019, Jul 27, 2017

Filed:

Apr 10, 2017

Appl. No.:

15/483589

Inventors:

- Tucson AZ, US
Brian D. Kelly - Tucson AZ, US
Eric J. May - Chandler AZ, US
Larry Morrison - Oro Valley AZ, US

International Classification:

G01N 1/30
G01N 33/58
G01N 33/543

Abstract:

Disclosed embodiments concern a composition comprising DAB chromogen, and/or derivative thereof, a stabilizer, and polymer capable of preventing or reducing DAB precipitation relative to a composition that does not comprise the polymer. Also disclosed herein is a method for using the disclosed composition and embodiments of a kit.