James Michael English

US Patent:

6352667, Mar 5, 2002

Filed:

Aug 24, 1999

Appl. No.:

09/379618

Inventors:

James P. English - Chelsea AL

Assignee:

Absorbable Polymer Technologies, Inc. - Pelham AL

International Classification:

B29C 4500

US Classification:

26432817, 623901

Abstract:

A method of making a biodegradable polymeric implant comprising the steps of aseptically mixing at least one monomer with at least one catalyst to form a polymerization mixture, injecting the polymerization mixture into a sterile mold, and polymerizing and/or cross-linking the polymerization mixture in the sterile mold to form a sterilized biodegradable polymeric implant. Additives may be included in the polymerization mixture as needed.

US Patent:

6987256, Jan 17, 2006

Filed:

May 24, 2004

Appl. No.:

10/853748

Inventors:

James E. English - Madison AL, US
William C. Pittman - Huntsville AL, US

Assignee:

The United States of America as represented by the Secretary of the Army - Washington DC

International Classification:

G01C 21/24
G01C 21/00
G02F 1/01

US Classification:

2502036, 2502061, 250225, 356 514, 359489, 359501

Abstract:

An improvement in a semi-active laser last pulse logic missile seeker is disclosed and claimed. In one embodiment, the improvement includes a first polarizer disposed in the detection field of view of the PIN photodiode detector and a second polarizer disposed in the detection field of view of the staring imaging infrared focal plane array. Each of the first and second polarizers has an identically configured plurality of segments. Each segment allows transmission of a different polarization than other segments and is sized to completely cover the fields of view of both the PIN photodiode detector and the staring imaging infrared focal plane array. First and second actuators are connected to the first and second polarizers, respectively, to synchronously and simultaneously step identical and corresponding segments in a plurality of discrete steps within the fields of view in response to incoming temporal and spatial laser returns.

US Patent:

7479535, Jan 20, 2009

Filed:

Feb 25, 2003

Appl. No.:

10/505529

Inventors:

Keith Branham - Pelham AL, US
Mahesh V. Chaubal - Ellicott City MD, US
James P. English - Chelsea AL, US
Donna Hall - Verbena AL, US
Zhong Zhao - Ellicott City MD, US

Assignee:

Guilford Pharmaceuticals, Inc. - Baltimore MD

International Classification:

C08G 79/02
C08G 79/04
C08G 79/00

US Classification:

528398, 528399, 528422, 528425

Abstract:

The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation.

US Patent:

7674875, Mar 9, 2010

Filed:

Jan 16, 2009

Appl. No.:

12/355359

Inventors:

Keith Branham - Pelham AL, US
Mahesh V. Chaubal - Ellicott City MD, US
James P. English - Chelsea AL, US
Donna Hall - Verbena AL, US
Zhong Zhao - Ellicott City MD, US

Assignee:

Eisai Inc. - Woodcliff Lake NJ

International Classification:

C08G 79/02
C08G 79/04
C08G 79/00

US Classification:

528398, 528399, 528422, 528425

Abstract:

The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation.

US Patent:

8101202, Jan 24, 2012

Filed:

Jun 9, 2005

Appl. No.:

11/570402

Inventors:

Keith Edward Branham - Pelham AL, US
James Perry English - Chelsea AL, US
Donald R. Cowsar - Savannah GA, US

Assignee:

Keraplast Technologies, Ltd - San Antonio TX

International Classification:

A61F 13/53
C07K 14/46
D06M 11/38

US Classification:

424443, 81275, 81281, 530357, 602 50

Abstract:

Useful materials are produced from keratin containing raw materials by a process that includes gentle lanthionization of cystine disulfide bonds. Hydratable materials are produced for use in medical and cosmetic applications.

US Patent:

8258255, Sep 4, 2012

Filed:

Jan 22, 2010

Appl. No.:

12/692233

Inventors:

Keith Branham - Pelham AL, US
Mahesh V. Chaubal - Ellicott City MD, US
James P. English - Chelsea AL, US
Donna Hall - Verbena AL, US
Zhong Zhao - Ellicott City MD, US

Assignee:

Eisai Inc. - Woodcliff Lake NJ

International Classification:

C08G 79/02
C08G 79/04
C08G 79/00

US Classification:

528398, 528399, 528422, 528425

Abstract:

The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation.

US Patent:

20130023688, Jan 24, 2013

Filed:

Jul 24, 2012

Appl. No.:

13/556660

Inventors:

Keith Branham - Pelham AL, US
Mahesh V. Chaubal - Ellicott City MD, US
James P. English - Chelsea AL, US
Donna Hall - Verbena AL, US
Zhong Zhao - Ellicott City MD, US

Assignee:

Eisai Inc. - Woodcliff Lake NJ

International Classification:

C07F 9/40

US Classification:

558 98

Abstract:

The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation.

US Patent:

52782026, Jan 11, 1994

Filed:

Dec 23, 1991

Appl. No.:

7/788159

Inventors:

Richard L. Dunn - Fort Collins CO
James P. English - Birmingham AL
Donald R. Cowsar - Birmingham AL
David D. Vanderbilt - Birmingham AL

Assignee:

Atrix Laboratories, Inc. - Fort Collins CO

International Classification:

C08L 6700
C08L 6900
C08L 7700
A61F 200

US Classification:

523113

Abstract:

A biodegradable polymer is provided for use in providing syringeable, in-situ forming, solid biodegradable implants for animals. The polymer is placed into the animal in liquid form and cures to form the implant in-situ. A thermoplastic system to form said implant comprises the steps of dissolving a non-reactive polymer in biocompatible solvent to form a liquid, placing the liquid within the animal, and allowing the solvent to dissipate to produce the implant. An alternative, thermosetting system comprises mixing together effective amounts of a liquid acrylic ester terminated, biodegradable prepolymer and a curing agent, placing the liquid mixture within an animal and allowing the prepolymer to cure to form the implant. Both systems provide a syringeable, solid biodegradable delivery system by the addition of an effective level of biologically active agent to the liquid before injection into the body.