Jeanne P Living Ellis

US Patent:

6429194, Aug 6, 2002

Filed:

Jun 22, 2001

Appl. No.:

09/888144

Inventors:

Charles D. Leahy - Concord MA
Edward J. Ellis - Lynnfield MA
Jeanne Y. Ellis - Lynnfield MA

Assignee:

Vista Scientific LLC - Andover MA

International Classification:

A61K 3816

US Classification:

514 8, 514912

Abstract:

Aqueous ophthalmic preparations are provided and are intended to be instilled into the eye, or in which to pre soak or store an object to be inserted into the eye, such as a contact lens, an ointment, or a solid device to be inserted into the conjunctival sac. The preparations disclosed are utilized for the treatment of a tear film and ocular surface disorder known as keratoconjunctivitis sicca or dry eye syndrome. In general, the preparations of this invention are also effective for the relief of symptoms of eye irritation, such as those caused by dry environmental conditions or by contact lens wear. In accordance with the present invention, the ophthalmic preparation includes a mucin component, similar to that found at the normal human ocular surface and in one exemplary and preferred embodiment, the mucin is a transmembrane or surface mucin.

US Patent:

6478881, Nov 12, 2002

Filed:

Feb 28, 2001

Appl. No.:

09/795766

Inventors:

Jeanne Y. Ellis - Lynnfield MA
Edward J. Ellis - Lynnfield MA

Assignee:

Vista Scientific L.L.C. - Andover MA

International Classification:

A61L 218

US Classification:

134 42, 134 39, 134 40, 514840, 510112, 510384, 510434, 510435, 510471, 510477, 510533, 510163, 510400, 510420, 510421, 510433, 510475

Abstract:

The present invention is based on the unexpected finding that the combination of a carboxylate containing anionic polymer, of molecular weight greater than about 1000 daltons, with cleaning agents, provides improved contact lens cleaning preparations. The present invention includes contacting a soiled contact lens with an aqueous solution comprising an anionically charged polymer and a surfactant or surfactant combination selected from the classes of nonionic surfactants, anionic surfactants, and amphoteric surfactants.

US Patent:

20040214754, Oct 28, 2004

Filed:

Mar 30, 2004

Appl. No.:

10/813998

Inventors:

Edward Ellis - Lynnfield MA, US
Charles Leahy - Concord MA, US
Jeanne Ellis - Lynnfield MA, US

International Classification:

A61K038/16

US Classification:

514/008000

Abstract:

The present invention relates to an aqueous formulation to be instilled into the eye, or in which to pre soak or store an object to be inserted into the eye, such as a contact lens, an ointment, or a solid device to be inserted into the conjunctival sac. The preparations disclosed are utilized for the treatment of a tear film and ocular surface disorder known as keratoconjunctivitis sicca or dry eye syndrome. In general, the preparations of this invention are also effective for the relief of symptoms of eye irritation, such as those caused by dry environmental conditions or by contact lens wear. In accordance with the present invention, the ophthalmic preparation includes a glycomacropeptide component, similar to that found at the normal human ocular surface and in one exemplary and preferred embodiment, the glycomacropeptide is derived from mammalian milk, preferably bovine.

US Patent:

20040220089, Nov 4, 2004

Filed:

Mar 30, 2004

Appl. No.:

10/814001

Inventors:

Edward Ellis - Lynnfield MA, US
Charles Leahy - Concord MA, US
Jeanne Ellis - Lynnfield MA, US

International Classification:

A61K038/38

US Classification:

514/008000

Abstract:

The present invention relates to an aqueous formulation to be instilled into the eye, or in which to pre soak or store an object to be inserted into the eye, such as a contact lens, an ointment, or a solid device to be inserted into the conjunctival sac. The preparations disclosed are utilized for the treatment of a tear film and ocular surface disorder known as keratoconjunctivitis sicca or dry eye syndrome. In general, the preparations of this invention are also effective for the relief of symptoms of eye irritation, such as those caused by dry environmental conditions or by contact lens wear. In accordance with the present invention, the ophthalmic preparation includes a glycoprotein component, similar to that found at the normal human ocular surface and in one exemplary and preferred embodiment, the glycoproteins are derived from mammalian milk, preferably bovine.

US Patent:

20040247681, Dec 9, 2004

Filed:

Jul 22, 2004

Appl. No.:

10/486130

Inventors:

Edward Ellis - Lynnfield MA, US
Jeanne Ellis - Lynnfield MA, US

International Classification:

A61K009/14

US Classification:

424/486000

Abstract:

Polymeric compositions containing a high percentage of bound polypropylene glycol provide matrices for the controlled release of drugs and medicinal agents. The compositions are prepared by the polymerization of ethylenically unsaturated polypropylene glycol containing monomers. Copolymers of ethylenically unsaturated polypropylene glycol containing monomers with co-monomers are also disclosed. The drug loaded polymeric compositions of this invention find particular utility as ocular insets for the controlled release of drug(s) into the eye.

US Patent:

20060198892, Sep 7, 2006

Filed:

Feb 22, 2006

Appl. No.:

11/359156

Inventors:

Jeanne Ellis - Andover MA, US
Edward Ellis - Andover MA, US

International Classification:

A61K 9/14

US Classification:

424486000

Abstract:

Polymeric compositions containing a high percentage of bound alkyl ether segments provide matrices and membranes for the controlled release of drugs and medicinal agents. The polymeric compositions are prepared by the polymerization of ethylenically unsaturated alkyl ether containing monomers. Copolymers of ethylenically unsaturated alkyl ether containing monomers with co-monomers are also disclosed. The drug loaded polymeric compositions of this invention find particular utility in the construction of controlled release devices.

US Patent:

20100178315, Jul 15, 2010

Filed:

Dec 8, 2009

Appl. No.:

12/633093

Inventors:

Jeanne Y. Ellis - Andover MA, US
Edward J. Ellis - Andover MA, US

Assignee:

Vista Scientific LLC - Andover MA

International Classification:

A61K 31/5377
A61F 2/00
A61P 27/06

US Classification:

424427, 5142362

Abstract:

Polymeric compositions containing a high percentage of bound alkyl ether segments provide matrices and membranes for the controlled release of drugs and medicinal agents. The polymeric compositions are prepared by the polymerization of ethylenically unsaturated alkyl ether containing monomers. Copolymers of ethylenically unsaturated alkyl ether containing monomers with co-monomers are also disclosed. The drug loaded polymeric compositions of this invention find particular utility in the construction of controlled release devices.

US Patent:

20100233241, Sep 16, 2010

Filed:

Mar 12, 2010

Appl. No.:

12/722713

Inventors:

Charles Leahy - Concord MA, US
Edward Ellis - Lynnfield MA, US
Jeanne Y. Ellis - Lynnfield MA, US

Assignee:

VISTA SCIENTIFIC LLC - Andover MA

International Classification:

A61F 2/00
A61K 38/13
A61K 31/5377
A61K 31/496
A61P 27/06
A61P 27/02

US Classification:

424428, 424427, 514 11, 5142362, 51425308

Abstract:

An ocular device for insertion into an eye is provided and includes a body having an anterior surface and a posterior surface for placement on one of superior sclera and inferior sclera of the eye. The posterior surface is defined by a base curve that is substantially identical to a radius of curvature of the one of the superior sclera and inferior sclera of the eye. In one embodiment, the ocular device serves as an ocular drug delivery system and contains an active pharmaceutical agent, a lubricant, etc. In a second embodiment the ocular device can be constructed in such a manner to treat a wide variety of ocular conditions and diseases.