Jena Jean Steinle from 10726 Davisburg Rd, Davisburg, MI 48350, age 49

Beta-Adrenergic Receptor Agonists And Uses Thereof
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US Patent:

20120329879, Dec 27, 2012
Filed:

Sep 7, 2012
Appl. No.:

13/607216
Inventors:

Jena J. Steinle - Olive Branch MS, US
Kimberly P. Williams - Memphis TN, US
Jayaprakash Pagadala - Memphis TN, US
Duane D. Miller - Germantown TN, US
Assignee:

THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION - Knoxville TN
International Classification:

A61K 31/137
C07C 215/56
C12N 5/071
A61P 27/02
US Classification:

514653, 564361, 435375
Abstract:

Provided herein are methods for improving function in a retinal cell associated with a diabetic condition and for treating a diabetic retinopathic condition in a subject. The methods comprise contacting the retinal cell or administering to the subject a beta-adrenergic receptor agonist or R-isomer thereof such as have the chemical structural formula:where Ris (CH)(CH)orwhere n is 1 to 4, Ris H or H.HX, where X is a halide and Ris O(CH)CHat one or more of C2-C6, where m is 0 to 4. Also provided are BAR agonists having the structural where Ris the (CH)-phenyl-Rsubstituent and the hydroxy-benzene moiety is 1,2-benzene diol or 1,3-benzene diol.

Methods And Materials For Treating Retinopathy
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US Patent:

20070112076, May 17, 2007
Filed:

Nov 15, 2006
Appl. No.:

11/599641
Inventors:

Jena Steinle - Carbondale IL, US
Assignee:

SOUTHERN ILLINOIS UNIVERSITY - Carbondale IL
International Classification:

A61K 31/138
US Classification:

514651000
Abstract:

The present invention is directed to topical ophthalmic compositions and methods for treating retinopathy.