Jennifer Renee Carroll

US Patent:

6750247, Jun 15, 2004

Filed:

May 31, 2002

Appl. No.:

10/159772

Inventors:

Phillip Crews - Santa Cruz CA
Jennifer Carroll - Santa Cruz CA
Theodore Holman - Santa Cruz CA
Guy Miller - Santa Clara CA
Steve Bobzin - Santa Clara CA
Lesley Brown - Santa Clara CA

Assignee:

Galileo Laboratories, Inc. - Santa Clara CA

International Classification:

A61K 3119

US Classification:

514456, 514461, 514569, 549407, 549502

Abstract:

Compounds that are effective lipoxygenase inhibitors, and methods and pharmaceutical compositions for inhibiting lipoxygenases and for treatment of lipoxygenase-mediated conditions in humans and other subjects. The compounds, methods and pharmaceutical compositions utilize subersic terpenoids, jaspic terpenoids, igernellic terpenoids, hippospongic terpenoids, halicondric terpenoids, dictyodendric terpenoids, and/or heteronemic terpenoids, and synthetic derivatives or analogs thereof. Exemplary compounds include (-)-subersic acid, (+)-subersin, jaspaquinol, (-)-jaspic acid, igernellin, halisufate 7, and hipposulfate C and D, and derivatives thereof.