A composition for reducing dentinal hypersensitivity and remineralizing exposed dentinal surface and open dentinal tubules, comprising a non-aqueous carrier and a desensitizing amount of a desensitizing/remineralizing agent which consists essentially of a water soluble calcium salt and an incompatible ingredient which would otherwise react with the calcium salt. Upon contact with saliva when applied to an oral cavity, the desensitizing/remineralizing is then formed in situ by the reaction between the calcium salt and the incompatible ingredient, thereby remineralizing exposed dentinal surface and open dentinal tubules.
Jin Xu - Livingston NJ, US Bala Nayar - Dayton NJ, US Marissa Healy - Denville NJ, US
International Classification:
A61K007/16
US Classification:
424/049000
Abstract:
A dentifrice gel or paste comprising from about 40% to 70% by weight baking soda, from about 0.5% to 5% by weight of a blend of natural ingredients, from about 0.5% to 5% by weight of a flavoring oil and a sufficient amount of a stabilizing combination of a xanthan gum binder, at least one betaine surfactant and a humectant comprising glycerin or glycerin and sorbitol in an amount sufficient to render the dentifrice formulation stable to degradation and resistant to syneresis and phase separation.
Marissa Healy - Denville NJ, US Bala Nayar - Dayton NJ, US Jin Xu - Livingston NJ, US
International Classification:
A61K007/16
US Classification:
424/049000
Abstract:
A dentifrice gel or paste comprising from about 40% to 70% by weight baking soda, from about 0.5% to 5% by weight of a blend of natural ingredients, from about 0.5% to 5% by weight of a flavoring oil and a sufficient amount of a stabilizing combination of a xanthan gum binder, at least one betaine surfactant and ahumectant comprising glycerin or glycerin and sorbitol in an amount sufficient to render the dentifrice formulation stable to degradation and resistant to syneresis and phase separation.
Principal Investigator, Professor at Institute of Neuroscience (ION), Chinese Academy of Sciences, Shanghai
Location:
Shanghai City, China
Industry:
Research
Work:
Institute of Neuroscience (ION), Chinese Academy of Sciences, Shanghai since 2010
Principal Investigator, Professor
Caritas St. Elizabeth's Medical Center 2003 - 2010
Associate Investigator, Assistant Professor
Children's Hospital Boston 1998 - 2003
Postdoctoral Fellow
Education:
Tulane University 1993 - 1998
Ph.D., Molecular Biology,
Dr. Xu graduated from the Anhui Med Univ, Hefei City, Anhui, China in 1984. He works in Flushing, NY and specializes in Child & Adolescent Psychiatry and Psychiatry.
Dr. Xu graduated from the Shanghai Med Univ, Shanghai First Med Univ, Shanghai, China in 1983. She works in Blandon, PA and specializes in Family Medicine. Dr. Xu is affiliated with Penn State Health St Joseph Medical Center and Reading Hospital & Medical Center.