John T Ho

US Patent:

8525022, Sep 3, 2013

Filed:

Jan 9, 2009

Appl. No.:

12/735382

Inventors:

John Ho - Cambridge MA, US
Vladimir Bulovic - Lexington MA, US
Tim Osedach - Cambridge MA, US

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

H01L 31/00

US Classification:

136263, 136255, 136256

Abstract:

A photovoltaic device includes a heterojunction between different semiconductor materials which are present in charge transporting layers. The device can include laterally-arranged electrodes.

US Patent:

20120115241, May 10, 2012

Filed:

Jul 21, 2010

Appl. No.:

12/840452

Inventors:

John Ho - Cambridge MA, US
Thomas Patrick Bidigare - Arlington VA, US

Assignee:

Raytheon BBN Technologies Corp. - Cambridge MA

International Classification:

G01N 21/76

US Classification:

436172, 422 681

Abstract:

Systems, devices and methods for remotely interrogating sensor electronics are described. In one embodiment, a system for detecting and localizing chemical analytes is described. This system includes a plurality of chemosensor electronic devices for detecting the presence of chemical analytes. Each of these devices includes a chemosensor for sensing chemical analytes, a transponder, and an electronic circuit for activating the transponder based on an output of the chemosensor. These devices may have a cross-section area of less than 1 square micrometer. The system also includes an interrogation device for interrogating the plurality of devices and for receiving information on the detected chemical analytes from devices with activated transponders, and a processor for determining the locations of the devices with activated transponders. These locations may be forwarded to a third party.

US Patent:

20210088433, Mar 25, 2021

Filed:

Sep 23, 2020

Appl. No.:

17/030032

Inventors:

- Billerica MA, US
David P. Marchessault - Newton MA, US
Christopher R. Saulnier - Medford MA, US
John C. Ho - Sudbury MA, US
Walid A. Atia - Jamaica Plain MA, US

International Classification:

G01N 15/02
G01N 21/53
G01N 15/14

Abstract:

A device for monitoring a bioreactor is configured for in-situ analysis, e.g., by NIR, without the need for withdrawing a sample into a sample cell or into an ex-situ arrangement. The device can be inserted into a port of the bioreactor and provides a sample detection region defined by an optical element such as a lens and a photodetector. The electrical signal obtained from a photodetector that is part of the device can be directed to an analyzer via a detachable electrical connection.

US Patent:

20210062133, Mar 4, 2021

Filed:

Aug 28, 2020

Appl. No.:

17/006172

Inventors:

- Billerica MA, US
David P. Marchessault - Newton MA, US
Christopher R. Saulnier - Medford MA, US
John C. Ho - Sudbury MA, US

International Classification:

C12M 1/26
G01N 21/359
C12M 1/12
C12M 1/34

Abstract:

A device for monitoring a bioreactor includes a sample tube for withdrawing a sample from a bioreactor into a sample cell and elements for analyzing the sample, in the NIR region, for example. Collecting and releasing the sample from and into the bioreactor is conducted using a peristaltic pump that is operated as a reversible/reciprocating pump. A sterile filter separates sample cell tubing from tubing connecting to the peristaltic pump.

US Patent:

20190358632, Nov 28, 2019

Filed:

May 22, 2019

Appl. No.:

16/419690

Inventors:

- Billerica MA, US
John C. Ho - Sudbury MA, US

International Classification:

B01L 3/00
C12M 1/12
C12M 1/34

Abstract:

A culture medium of a micro-physiological (MP) system is analyzed by near infrared (NIR) absorption spectroscopy. The MP system can be microfluidic or a well-plate MP system. Spectra are obtained in real time and are analyzed to provide information such as, for example, the concentration of one or more analytes as a function of time.