Julie Ann Boyer

US Patent:

7022496, Apr 4, 2006

Filed:

Jul 13, 2001

Appl. No.:

09/904698

Inventors:

Gary Ketner - Columbia MD, US
Julie L. Boyer - New York NY, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

C12P 21/00

US Classification:

435 691, 4241841, 4242331, 4242041, 4242771, 4242781, 530300, 530350, 530 2372

Abstract:

The present invention provides a modified adenovirus comprising genomic adenoviral DNA which has been modified so that (i) the only gene product of the early region (E4) that is expressed is open reading frame 6 (ORF-6), (ii) neither the gene product of the E1A region nor the gene product of the E1B region is expressed, and (iii) no other early or late gene products are expressed. The present invention also provides methods of inhibiting repair of breaks in double-stranded DNA in a cell, preventing concatamerization of linear wild-type adenoviral DNA, inhibiting V(D)J recombination of nucleic acid sequences encoding immunoglobulins, preventing apoptosis, and preventing and treating cancer.

US Patent:

20180291154, Oct 11, 2018

Filed:

Jun 15, 2018

Appl. No.:

16/009366

Inventors:

- WATERFORD NY, US
Julie L. Boyer - Columbia MD, US

International Classification:

C08G 77/08
C09D 143/04
C07F 7/18
C07F 7/14
C07F 7/08
C09D 183/04
C08G 77/00
C07F 7/12

Abstract:

A process and composition for the hydrosilylation of an unsaturated compound comprising reacting (a) a silyl hydride with (b) an unsaturated compound in the presence of (c) a platinum compound and (d) a cyclodiene, with the proviso that when the unsaturated compound is a terminal alkyne, the silyl hydride is other than a halosilane. The process and composition optionally comprise an inhibitor (e). The process and composition may be employed to form a variety of hydrosilylation products.

US Patent:

20180015449, Jan 18, 2018

Filed:

Sep 26, 2017

Appl. No.:

15/715324

Inventors:

- Waterford NY, US
- Princeton NY, US
Julie Boyer - Columbia MD, US
Paul Chirik - Princeton NJ, US
Johannes G.P. Delis - Bergen op Zoom, NL
Kenrick Lewis - Flushing NY, US
Susan A. Nye - Feura Bush NY, US

International Classification:

B01J 31/18

Abstract:

Disclosed herein is the use of manganese, iron, cobalt, or nickel complexes containing tridentate pyridine di-imine ligands as hydrosilylation catalysts. These complexes are effective for efficiently catalyzing hydrosilylation reactions, as well as offering improved selectivity and yield over existing catalyst systems.