Kimberly A Gallagher

US Patent:

8093295, Jan 10, 2012

Filed:

May 16, 2006

Appl. No.:

11/663165

Inventors:

Jeannie Chow Wong - Jersey City NJ, US
Benjamin Max Cohen - Cranford NJ, US
Aaron S. Cote - West Windsor NJ, US
Erik A. Dienemann - Metuchen NJ, US
Kimberly Gallagher - Green Lane PA, US
Craig Ikeda - Harleysville PA, US
Justin Moser - Collegeville PA, US
Pavol Rajniak - Lansdale PA, US
Robert A. Reed - Line Lexington PA, US
Brian Sell - Royersford PA, US
Cindy Starbuck - Doylestown PA, US
Hsien-Hsin Tung - Grayslake IL, US
Qingxi Wang - Ambler PA, US
Vincent R. Capodanno - Hillsborough NJ, US

Assignee:

Merck Sharp & Dohme Corp. - Rahway NJ

International Classification:

A61K 31/19

US Classification:

514575, 514613, 514619, 564161

Abstract:

The present invention provides a pharmaceutical composition or crystalline composition with a specific dissolution profile, which comprises suberoylanilide hydroxamic acid or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. The present invention provides a process of producing said crystalline composition or pharmaceutical composition. The present invention also provides compositions with a specific particle size distribution.