Mary Suzanne Peters

US Patent:

20060171890, Aug 3, 2006

Filed:

Jan 27, 2006

Appl. No.:

11/342246

Inventors:

David Yeomans - Stanford CA, US
Martin Angst - Stanford CA, US
Michael Peters - Stanford CA, US
Mary Peters - Hobart IN, US

International Classification:

A61K 49/00

US Classification:

424009200

Abstract:

Methods for evaluating the activity of candidate agents are provided. In practicing the subject methods, a candidate agent is administered to an injured tissue site of an animal and the activity of the candidate agent on the injured tissue site is evaluated. Also provided are kits and systems for use in practicing the subject methods.

US Patent:

20060211021, Sep 21, 2006

Filed:

Feb 24, 2006

Appl. No.:

11/361101

Inventors:

David Yeomans - Stanford CA, US
Michael Peters - Hobart IN, US
William Gilly - Pacific Grove CA, US
Mary Peters - Hobart IN, US

International Classification:

C12Q 1/68
C12N 5/08
C12N 15/87

US Classification:

435006000, 435455000, 435368000

Abstract:

Methods and compositions are provided for determining whether target, e.g., an endogenous or novel (non-endogenous), nucleic acid sequence of a neuronal cell is involved in sensory function. In practicing the subject methods, a neuronal cell selective vector including a modulating domain for a neuronal cell nucleic acid sequence, optionally having a domain encoding a directly detectable product, is administered to an animal. Sensory function in harvested neuronal cells is then evaluated to determine whether the target nucleic acid sequence is involved in sensory function. Also provided are compositions, kits, and systems for practicing the subject methods.