Peter J Lu

US Patent:

20100124758, May 20, 2010

Filed:

Nov 13, 2009

Appl. No.:

12/618343

Inventors:

Melanie Margarete Hoehl - Cambridge MA, US
Peter James Lu - Cambridge MA, US
Alexander H. Slocum - Bow NH, US

International Classification:

C12Q 1/32
C12Q 1/28
C12M 1/34
G01N 21/64

US Classification:

435 26, 435 28, 4352887, 2504591, 356 51, 356432

Abstract:

A method and apparatus are provided for detecting contaminants, such as ethylene glycol and diethylene glycol, in various materials, including household products, and medicines. The contaminants can be detected using enzyme assays that produce measurable changes in light absorption and/or light fluorescence.

US Patent:

20100195868, Aug 5, 2010

Filed:

May 30, 2008

Appl. No.:

12/601885

Inventors:

Peter J. Lu - Cambridge MA, US

International Classification:

G06T 7/00

US Classification:

382103

Abstract:

Presented herein is a real-time target-locking confocal microscope that follows an object moving along an arbitrary path, even as it simultaneously changes its shape, size and orientation. This Target-locking Acquisition with Realtime Confocal (TARC) microscopy system integrates fast image processing and rapid image acquisition using, for example, a Nipkow spinning-disk confocal microscope. The system acquires a 3D stack of images, performs a full structural analysis to locate a feature of interest, moves the sample in response, and then collects the next 3D image stack. In this way, data collection is dynamically adjusted to keep a moving object centered in the field of view. The system's capabilities are demonstrated by target-locking freely-diffusing clusters of attractive colloidal particles, and actively-transported quantum dots (QDs) endocytosed into live cells free to move in three dimensions for several hours. During this time, both the colloidal clusters and live cells move distances several times the length of the imaging volume. Embodiments may be applied to other applications, such as manufacturing, open water observation of marine life, aerial observation of flying animals, or medical devices, such as tumor removal.

US Patent:

20130157350, Jun 20, 2013

Filed:

Feb 13, 2013

Appl. No.:

13/766269

Inventors:

Robert Bosch GmbH - Stuttgart, DE
Melanie Margarete Hoehl - Cambridge MA, US
Peter James Lu - Cambridge MA, US

Assignee:

Robert Bosch GmbH - Stuttgart

International Classification:

C12Q 1/32

US Classification:

4352887

Abstract:

A method and apparatus are provided for detecting contaminants, such as ethylene glycol and diethylene glycol, in various materials, including household products, and medicines. The contaminants can be detected using enzyme assays that produce measurable changes in light absorption and/or light fluorescence.