Qun Yi Zheng

US Patent:

6361815, Mar 26, 2002

Filed:

Dec 21, 1998

Appl. No.:

09/217642

Inventors:

Bo Lin Zheng - Wayne NJ
Calvin Hyungchan Kim - Fort Lee NJ
Kan He - River Edge NJ
Qun Yi Zheng - Wayne NJ

Assignee:

Pure World Botanicals, Inc. - South Hackensack NJ

International Classification:

A61K 3105

US Classification:

426489, 426425, 426429, 426478, 514733, 514736

Abstract:

Provided are products including trihydroxystilbenes and glycosylated derivatives thereof. Also provided are compositions containing these products with an aqueous solvent, particularly and alcohol-water mixture, and reverse phase chromatographic methods for isolating and purifying the compositions from plant materials. The products have biological activity, including anti-tumor activity.

US Patent:

6469050, Oct 22, 2002

Filed:

Oct 16, 2000

Appl. No.:

09/688753

Inventors:

Christopher K. Murray - Longmont CO 80503
Qun Y. Zheng - Wayne NJ 07470
Sagar R. Shakya - Brantford, Ontario, CA

International Classification:

A61K 31337

US Classification:

514449, 549510, 549511

Abstract:

An antitumor compound of formula (5): Also provided by the present invention is a method of preparing a compound of formula (5) whereby diesterification of the alcohol groups located at the 2âand 7 positions of paclitaxel is followed by the hydrolysis of the 2âhexanoate group resulting in 7-hexanoyltaxol.

US Patent:

6552206, Apr 22, 2003

Filed:

May 2, 2002

Appl. No.:

10/138030

Inventors:

Bo Lin Zheng - Aurora CO
Kan He - River Edge NJ
Yu Shao - Ledgewood NJ
Qun Yi Zheng - Wayne NJ

Assignee:

Pure World Botanicals, Inc. - South Hackensack NJ

International Classification:

C07C23100

US Classification:

554 36, 564200, 424725, 554 35

Abstract:

The invention relates to compositions that can be isolated from Lepidium plant material and to methods for their isolation. The compositions are useful for treating and preventing cancer and sexual dysfunction.

US Patent:

RE38117, May 6, 2003

Filed:

Nov 21, 2000

Appl. No.:

09/717815

Inventors:

Qun Y. Zheng - Wayne NJ
Christopher Murray - Longmont CO
Randall J. Daughenbaugh - Rapid City SD
Poonsakdi Ploypradith - Wangthongland, TH
Gary H. Posner - Baltimore MD

Assignee:

Hauser, Inc. - Boulder CO
Johns Hopkins - Baltimore MD

International Classification:

C07D32102

US Classification:

549349, 549220, 5462817

Abstract:

Described herein are novel trioxane dimers of structure which possess antiproliferative and antitumor activities.

US Patent:

6682697, Jan 27, 2004

Filed:

Jan 15, 2002

Appl. No.:

10/046927

Inventors:

Kan He - River Edge NJ
Baoliang Cui - Palisade Park NJ
Zhong Guan Shao - Saddle Brook NJ
Natalie I. Koether - Far Hills NJ
Val Madis - Ho Ho Kus NJ
Qun Yi Zheng - Wayne NJ

Assignee:

Pure World Botanicals, Inc. - South Hackensack NJ

International Classification:

A61C 200

US Classification:

422 29, 422 1, 422 21, 422 22, 422 23, 422 24, 422 28, 422 32, 422 34, 426321, 426331, 426335

Abstract:

The present invention relates generally to the sterilization and disinfection of agricultural and botanical products such as botanical powders. More particularly, the present invention is directed towards the use of HBS technology whereby contaminated agricultural products are contacted, at ambient pressure, with an oxidant such as nascent oxygen or hydroxyl radicals thus resulting in the oxidization and destruction of the contaminating microorganisms.

US Patent:

6753345, Jun 22, 2004

Filed:

Jul 19, 2002

Appl. No.:

10/199826

Inventors:

Christopher K. Murray - Longmont CO
Qun Y. Zheng - Wayne NJ
Sagar R. Shakya - Brantford, CA

Assignee:

Hauser, Inc. - El Segundo CA

International Classification:

A61K 31337

US Classification:

514449, 549510, 549511

Abstract:

An antitumor compound of formula (5): Also provided by the present invention is a method of preparing a compound of formula (5) whereby diesterification of the alcohol groups located at the 2â and 7 positions of paclitaxel is followed by the hydrolysis of the 2â hexanoate group resulting in 7-hexanoyltaxol.

US Patent:

6878731, Apr 12, 2005

Filed:

Aug 14, 2002

Appl. No.:

10/219056

Inventors:

Baoliang Cui - Palisade Park NJ, US
Bo Lin Zheng - Aurora CO, US
Kan He - River Edge NJ, US
Qun Yi Zheng - Wayne NJ, US

Assignee:

Pure World Botanicals, Inc. - South Hackensack NJ

International Classification:

A61K031/415

US Classification:

514385, 514396

Abstract:

The present invention relates to novel imidazole alkaloid compounds that have been isolated as a form of chloride salt from a root extract of Walp, with the common name Maca, and identified below as 1,3-bis(phenylmethyl)-4,5-dimethyl-1H-imidazlium chloride and 1,3-bis(phenylmethyl)-2,4,5-trimethyl-1H-imidazlium chloride, compounds (1) and (2), respectively. The present invention further relates to the use of these novel compounds (1) and (2) to treat proliferative diseases, such as but not limited to cancer.

US Patent:

RE43005, Dec 6, 2011

Filed:

Nov 21, 2007

Appl. No.:

11/943867

Inventors:

Bo Lin Zheng - Aurora CO, US
Kan He - River Edge NJ, US
Yu Shao - Ledgewood NJ, US
Qun Yi Zheng - Wayne NJ, US

Assignee:

Naturex Inc. - South Hackensack NJ

International Classification:

C07C 231/00
C07C 233/00
A01N 65/00

US Classification:

554 36, 564200, 424725, 554 35

Abstract:

The invention relates to compositions that can be isolated from Lepidium plant material and to methods for their isolation. The compositions are useful for treating and preventing cancer and sexual dysfunction.