Robert J Downs

US Patent:

20050058577, Mar 17, 2005

Filed:

Apr 7, 2004

Appl. No.:

10/821127

Inventors:

Kenneth Micklash - Royal Oak MI, US
Robert Downs - La Jolla CA, US
Jim Chang - San Diego CA, US
James Mainquist - San Diego CA, US

Assignee:

IRM, LLC - Hamilton

International Classification:

B01L003/00

US Classification:

422099000, 422102000

Abstract:

The present invention provides material removal heads and devices for noninvasively removing materials from the wells of multi-well plates. The material removal heads of the invention are structured to prevent cross-contamination among wells of multi-well plates as materials are removed from the plates. The invention also provides dispense heads and devices that include angled dispensers. Related systems, kits, and methods are additionally provided.

US Patent:

20060051247, Mar 9, 2006

Filed:

Aug 3, 2005

Appl. No.:

11/198918

Inventors:

Kenneth Micklash - Royal Oak MI, US
Robert Downs - La Jolla CA, US
Jim Chang - San Diego CA, US
James Mainquist - San Diego CA, US

Assignee:

IRM, LLC - Hamilton

International Classification:

B01L 3/02

US Classification:

422100000

Abstract:

The present invention provides fluid removal heads and related multi-well container processing systems for the efficient removal of fluids from multi-well containers. Methods of removing fluid from multi-well containers are also provided.

US Patent:

20070105214, May 10, 2007

Filed:

Nov 9, 2005

Appl. No.:

11/271501

Inventors:

Kenneth Micklash - Royal Oak MI, US
Jiyong Hong - Chapel Hill NC, US
James Mainquist - San Diego CA, US
Sheng Ding - San Diego CA, US
Robert Downs - La Jolla CA, US
Peter Schultz - La Jolla CA, US

Assignee:

IRM, LLC - Hamilton
THE SCRIPPS RESEARCH INSTITUTE - La Jolla CA

International Classification:

C12M 3/08
B01L 3/00
C12M 1/34

US Classification:

435306100, 435286200, 435287300, 422063000, 422099000

Abstract:

High throughput and automated cellular disruption systems that substantially uniformly disrupt cells as part of cellular motility assays as wells as other assay types are provided. In addition, various system components, including holding blocks, holding block loading devices, and system software, are also provided. Moreover, related methods that utilize these systems and system components are additionally provided.

US Patent:

47562137, Jul 12, 1988

Filed:

Jun 1, 1987

Appl. No.:

7/056231

Inventors:

James K. Mainquist - Mt. Clemens MI
Robert B. Deady - Plymouth MI
Robert C. Downs - Ortonville MI

Assignee:

Saturn Corporation - Troy MI

International Classification:

B60K 4118
B60K 4116
B60K 2010

US Classification:

74866

Abstract:

A hydraulic transmission control uses a plurality of solenoid valves to control the engagement of friction devices during the shifting of a transmission between gear ratios. A clutch priority valve is provided to prevent the continuous simultaneous engagement of friction devices which will establish more than one ratio. Also provided is a manually controlled valve which permits the operator to determine the range in which the transmission will operate. If the clutch priority valve has been actuated, the transmission ratio can be controlled between a low ratio, for example, second gear, and a high ratio, for example, third or fourth gear, by use of the manual valve in combination with an actuator mode valve. The clutch priority valve, when actuated, is also operable to disengage a torque converter clutch.