Robert Russell Lake

US Patent:

20050239064, Oct 27, 2005

Filed:

Jun 18, 2002

Appl. No.:

10/481596

Inventors:

Spyridon Artavanis-Tsakonas - Willard Road Brookline MA, US
Robert Lake - Malden MA, US

International Classification:

C12Q001/68
G01N033/53
A61K039/395
C12N015/85
A61K048/00

US Classification:

435006000, 435007100, 435455000, 514044000, 424143100

Abstract:

The invention is directed to methods of modulating Notch signal transduction and to complexes of the protein Mastermind with proteins identified as interacting with Mastermind by a two-hybrid screen as well as a complex of Mastermind (Mam) with Mip1, or a complex of Mam with Mip30, or a complex of Mam with Mip6. Methods of screening the complexes for efficacy in treating and/or preventing certain diseases and disorders, particularly hyperproliferative and cancerous conditions are also provided. The invention includes nucleic acid and amino acid sequences of Mip30 or Mip6, as well as fragments and derivatives thereof.

US Patent:

59006790, May 4, 1999

Filed:

Jun 11, 1998

Appl. No.:

9/096043

Inventors:

Robert Lake - Wakefield MA
William E. Sheehan - Melrose MA

Assignee:

Maximum Products Inc. - Wakefield MA

International Classification:

B60Q 126

US Classification:

307 108

Abstract:

According to the present invention, a lighting control circuit is provided in which various logic gates, transistors and other smaller-scale circuit elements are combined. The circuit receives as inputs the control signals from the vehicle, including the left and right indicator signals, the brake signal and the tail light signal. Each of these signals is fed into a first bank of logic gates whose outputs are supplied to a second bank of logic gates, whose output is in turn supplied to two transistors, each connected to a separate single filament bulb, one for the left side of the vehicle and the other for the right side.

US Patent:

D3846288, Oct 7, 1997

Filed:

Feb 27, 1996

Appl. No.:

D/050828

Inventors:

Robert Lake - Wakefield MA

International Classification:

1216

US Classification:

D12193

US Patent:

D3789985, Apr 29, 1997

Filed:

Feb 27, 1996

Appl. No.:

D/050820

Inventors:

Robert Lake - Wakefield MA

US Classification:

D12193

US Patent:

57675899, Jun 16, 1998

Filed:

Sep 3, 1996

Appl. No.:

8/707105

Inventors:

Robert C. Lake - Wakefield MA
William E. Sheehan - Melrose MA

Assignee:

Maximum Products Inc. - Wakefield MA

International Classification:

B60Q 126

US Classification:

307 108

Abstract:

According to the present invention, a lighting control circuit is provided in which various logic gates, transistors and other smaller-scale circuit elements are combined. The circuit receives as inputs the control signals from the vehicle, including the left and right indicator signals, the brake signal and the tail light signal. Each of these signals is fed into a first bank of logic gates whose outputs are supplied to a second bank of logic gates, whose output is in turn supplied to two transistors, each connected to a separate single filament bulb, one for the left side of the vehicle and the other for the right side.