Described herein are compositions and methods for using these compositions in the treatment of cancer, tumors, and tumor-related disorders in a subject.
Oral Pharmaceutical Formulations And Methods For Producing And Using Same
Robert Mansfield - Carlsbad CA, US Edgar Ulm - Encinitas CA, US Gregg Timony - San Diego CA, US
International Classification:
A61K 31/33 A61K 9/00
US Classification:
424400000, 514183000
Abstract:
Oral pharmaceutical formulations and methods of producing and using the same are described and claimed. The formulations are dispersions of phospholipids and one or more pharmacologically active compounds, In preferred embodiments, the pharmaceutically active compounds are ansamycins, pharmaceutically acceptable salts, or prodrugs thereof.
Drug Formulations Having Long And Medium Chain Triglycerides
Edqar Ulm - Encinitas CA, US Robert Mansfield - Carlsbad CA, US Marcus Boehm - San Diego CA, US
Assignee:
Conforma Therapeutics Corporation - San Diego CA
International Classification:
A61K 31/685 A61K 31/33
US Classification:
514183000, 514078000, 514547000
Abstract:
Drug formulations having emulsifying agents and both medium and long chain triglycerides are described. In preferred embodiments, the long chain triglycerides negate or lessen deleterious central nervous system effects that are caused by medium chain triglycerides.
Phospholipid-Based Pharmaceutical Formulations And Methods For Producing And Using Same
Edgar Ulm - San Diego CA, US Robert Mansfield - Carlsbad CA, US Gregg Timony - San Diego CA, US Marcus Boehm - San Diego CA, US
International Classification:
A61K 31/397 A61K 31/33 A61K 9/127
US Classification:
424450000, 514183000, 514210210
Abstract:
Pharmaceutical formulations and methods of producing and using the same are described and claimed. The formulations are dispersions of phospholipids and one or more pharmacologically active compounds, pharmaceutically acceptable salts thereof, or prodrugs thereof. In specific embodiments, the pharmaceutically active compounds are ansamycins and the overall formulation is substantially devoid of medium and long chain triglycerides.
Robert Mansfield - Carlsbad CA, US Edgar Ulm - Encinitas CA, US
Assignee:
CONFORMA THERAPEUTICS CORPORATION - San Diego CA
International Classification:
A61K 31/395
US Classification:
514183000
Abstract:
Provided are pharmaceutical compositions containing an oil phase and an aqueous phase, the oil phase including an ansamycin and less than 2% w/w oleic acid, wherein the ansamycin is geldanamycin, 17-aminogeldanamycin, 17-allyalamino-17-demethoxy-geldanamycin, compound 563, or compound 237 having the structures below, or a salt of any one of the aforementioned ansamycins
Oral Pharmaceutical Formulations And Methods For Producing And Using Same
Robert K. Mansfield - Carlsbad CA, US Edgar H. Ulm - Encinitas CA, US Gregg A. Timony - San Diego CA, US
International Classification:
A61K 31/395 A61P 31/00
US Classification:
514183
Abstract:
Oral pharmaceutical formulations and methods of producing and using the same are described and claimed. The formulations are dispersions of phospholipids and one or more pharmacologically active compounds, In preferred embodiments, the pharmaceutically active compounds are ansamycins, pharmaceutically acceptable salts, or prodrugs thereof.
Combination Therapy For The Treatment Of Cancer Using Cox-2 Inhibitors And Dual Inhibitors Of Egfr [Erbb1] And Her-2 [Erbb2]
Thomas M. Estok - Carlsbad CA, US Sara L. Zaknoen - Carlsbad CA, US Robert K. Mansfield - Carlsbad CA, US
Assignee:
TRAGARA PHARMACEUTICALS, INC - San Diego CA
International Classification:
A61K 31/517 A61K 31/7068 A61P 35/00
US Classification:
514 49, 51426624, 5142662
Abstract:
Described herein are compositions and methods for using these compositions in the treatment of cancer, tumors, and tumor-related disorders in a subject.
Therapies For Treating Cancer Using Combinations Of Cox-2 Inhibitors And Aromatase Inhibitors Or Combinations Of Cox-2 Inhibitors And Estrogen Receptor Antagonists
Thomas M. Estok - Carlsbad CA, US Sara L. Zaknoen - Carlsbad CA, US Robert K. Mansfield - Carlsbad CA, US Tracy Lawhon - Encinitas CA, US
Assignee:
Tragara Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31/5685 A61K 31/4196 A61P 35/00 A61K 31/402
US Classification:
514171, 514427, 514383
Abstract:
Described herein are compositions and methods for using these compositions in the treatment of cancer, tumors, and tumor-related disorders in a subject.
Isbn (Books And Publications)
Industrial Sites in the Vale of Castiard: The Work of William H. Townley
Brian Evans, Jake Skaggs, Mark Montgomery, Gary Walton, Sarah Lowenberg, Jason Bigguns, Heather Hensley, Heather Weber, Joshua Gray, Sam Jarrett, Christopher Miller