Robert H Mercer

US Patent:

7413910, Aug 19, 2008

Filed:

Mar 8, 2002

Appl. No.:

10/471121

Inventors:

Patrick Kearney - San Francisco CA, US
David Clarence Hager - San Jose CA, US
Douglas O. Keller - Lake Oswego OR, US
Jeffrey D. Donaldson - Tigard OR, US
Robert D. Mercer - Cornelius OR, US
James William Leahy - San Leandro CA, US
Micheal Morrissey - Danville CA, US
Troy M. Swartwood - Seattle WA, US

Assignee:

Exelixis, Inc. - South San Francisco CA

International Classification:

G01N 1/10

US Classification:

436180, 422102

Abstract:

A multi-well assembly () comprises a multi-well block () and a guide plate (). The multi-well block () has a plurality of wells () each with a fluid-impermeable bottom surface (). The guide plate () has a plurality of fluid passageways () corresponding to the wells () of the multi-well block (). The guide plate () is configured to establish fluid communication between each well () and an associated fluid passageway () when the guide plate () is aligned with the multi-well block ().

US Patent:

20050226786, Oct 13, 2005

Filed:

Mar 10, 2004

Appl. No.:

10/797978

Inventors:

David Hager - San Francisco CA, US
Jeffrey Donaldson - Tigard OR, US
Patrick Kearney - San Francisco CA, US
Douglas Keller - Lake Oswego OR, US
James Leahy - San Leandro CA, US
Robert Mercer - Cornelius OR, US
Michael Morrissey - Danville CA, US
Troy Swartwood - Seattle WA, US

International Classification:

B01L003/00
G01N001/00

US Classification:

422102000, 422099000, 436174000

Abstract:

A multi-well assembly according to one embodiment comprises a multi-well block and a guide plate. The multi-well block defines a plurality of wells, with each well having a fluid-impermeable bottom surface. The guide plate defines a plurality of fluid passageways corresponding to the wells of the multi-well block. The guide plate is configured such that, whenever the guide plate is registered with the multi-well block, fluid communication is established between each well and an associated fluid passageway. The guide plate enables iterative chemical or biological processes using multiple multi-well blocks. A seal plate is configured to cut fluid communication conferred by the guide plate via registration with the guide plate, or via registration with the multi-well block (once the guide plate is removed). The seal plate allows iterative chemical or biological processes within a single multi-well block.