Robert D Webster

US Patent:

6841381, Jan 11, 2005

Filed:

Jan 27, 1994

Appl. No.:

08/187879

Inventors:

Harriet L. Robinson - Southboro MA, US
Ellen F. Fynan - Sterling MA, US
Robert G. Webster - Memphis TN, US
Shan Lu - Northboro MA, US

Assignee:

University of Massachusetts Medical Center - Worcester MA
St. Jude Children's Research Hospital - Memphis TN

International Classification:

C12N 1563
C12N 1500

US Classification:

4353201, 435 691, 435325, 435455

Abstract:

This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated immune response can provide protection against infection by pathogenic agents, provide an anti-tumor response, or provide contraception. The host can be any vertebrate, avian or mammal, including humans.

US Patent:

20060212474, Sep 21, 2006

Filed:

Mar 16, 2005

Appl. No.:

11/083760

Inventors:

Thomas McCormack - Concord MA, US
Matthew Seegmiller - Somerville MA, US
Robert Webster - Groveland MA, US

Assignee:

Muzzy Lane Software Incorporated - Newburyport MA

International Classification:

G06F 17/00

US Classification:

70710300Z

Abstract:

Specifying content using data-driven systems is described, including creating a definition, the definition having a type and a property, instantiating the property, deriving a property value for the property using a linkage, and synchronously pushing an update to the property value over the linkage. Also described are building an object and a backing class, the object having a definition and a property for the definition, relating the backing class to the object based on the definition, and identifying a relationship between the object and another object, the object and the another object being related based on the backing class.

US Patent:

56435789, Jul 1, 1997

Filed:

Jan 27, 1993

Appl. No.:

8/009833

Inventors:

Harriet L. Robinson - Southboro MA
Ellen F. Fynan - Sterling MA
Robert G. Webster - Memphis TN

Assignee:

University of Massachusetts Medical Center - Worcester MA
St. Jude Children's Research Hospital - Memphis TN

International Classification:

A61K 39145
A61K 3900
C07H 2104
C12N 1511

US Classification:

4242101

Abstract:

This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated immune responses can provide protection against infection by pathogenic agents, provide an anti-tumor responses, or provide contraception. The host can be any vertebrate, avian or mammal, including humans.

US Patent:

20160346513, Dec 1, 2016

Filed:

May 25, 2016

Appl. No.:

15/164257

Inventors:

- Nashville TN, US
Peter York - Somerville MA, US
Hunter B. Gilbert - Nashville TN, US
Robert J. Webster - Nashville TN, US
Arthur W. Mahoney - Nashville TN, US
Patrick Wellborn - Nashville TN, US

International Classification:

A61M 25/01
A61B 17/34

Abstract:

The needle-sized surgical tools used in arthroscopy, otolaryngology, and other surgical fields could become even more valuable to surgeons if endowed with the ability to navigate around sharp corners to manipulate or visualize tissue. A needle-sized bendable joint design that grants this ability. It can be easily interfaced with manual tools or concentric tube robots and is straightforward and inexpensive to manufacture. The bendable joint includes of a nitinol tube with several asymmetric cutouts, actuated by a tendon.