Roland J Roy

US Patent:

20130310911, Nov 21, 2013

Filed:

Jul 19, 2013

Appl. No.:

13/946338

Inventors:

Damien Craig Rodger - South Pasadena CA, US
Andy Fong - Los Angeles CA, US
Victor Reggie Edgerton - Los Angeles CA, US
Roland R. Roy - Playa Vista CA, US
Yury Gerasimenko - Los Angeles CA, US
Igor Lavrov - Rancho Palos Verdes CA, US
Susan J. Harkema - Louisville KY, US
Claudia A. Angeli - Louisville KY, US

Assignee:

California Institute of Technology - Pasadena CA
University of Louisville Research Foundation, Inc. - Louisville KY
The Regents of the University of California - Oakland CA

International Classification:

A61N 1/05

US Classification:

607117, 427 21, 216 17

Abstract:

An implantable electrode array assembly configured to apply electrical stimulation to the spinal cord. A substantially electrically nonconductive layer of the device has a first portion positionable alongside the spinal cord that includes a plurality of first openings. The layer has a second portion that includes a plurality of second openings. Electrodes and traces are positioned inside a peripheral portion of a body portion of the device and alongside the layer. At least one of the first openings is adjacent each of the electrodes to provide a pathway through which the electrode may provide electrical stimulation to the spinal cord. At least one of the second openings is adjacent each of the traces to provide a pathway through which the trace may receive electrical stimulation. At least one trace is connected to each electrode and configured to conduct electrical stimulation received by the trace(s) to the electrode.

US Patent:

20220313993, Oct 6, 2022

Filed:

Jun 10, 2022

Appl. No.:

17/837913

Inventors:

- Oakland CA, US
Victor Reggie Edgerton - Los Angeles CA, US
Roland R. Roy - Playa Vista CA, US
Daniel C. Lu - Los Angeles CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61N 1/36
A61K 31/00
A61K 31/197
A61N 1/04
G16H 20/40

Abstract:

In various embodiments, non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries are provided. In some embodiments the methods involve administering transcutaneous electrical spinal cord stimulation (tSCS) to the mammal at a frequency and intensity that induces locomotor activity.

US Patent:

20210378991, Dec 9, 2021

Filed:

Aug 19, 2021

Appl. No.:

17/407043

Inventors:

- Oakland CA, US
V. Reggie Edgerton - Los Angeles CA, US
Roland R. Roy - Playa Vista CA, US
Yury P. Gerasimenko - Los Angeles CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61K 31/137
A61N 1/05
A61N 1/36
A61K 31/4168
A61K 31/4178
A61K 31/496
A61K 31/4985
A61K 31/506
A61K 31/517
A61K 31/527

Abstract:

In various embodiments, methods are provided for applying transcutaneous and/or epidural spinal cord stimulation with and without selective pharmaceuticals to restore voluntary control of hand function in tetraplegic subjects.

US Patent:

20190167987, Jun 6, 2019

Filed:

Nov 26, 2018

Appl. No.:

16/200467

Inventors:

- Oakland CA, US
V. Reggie Edgerton - Los Angeles CA, US
Roland R. Roy - Playa Vista CA, US
Yury P. Gerasimenko - Los Angeles CA, US

International Classification:

A61N 1/36
A61K 31/517
A61K 31/506
A61K 31/4985
A61K 31/496
A61K 31/4178
A61K 31/527
A61K 31/137
A61N 1/05
A61K 31/4168

Abstract:

In various embodiments, methods are provided for applying transcutaneous and/or epidural spinal cord stimulation with and without selective pharmaceuticals to restore voluntary control of hand function in tetraplegic subjects.

US Patent:

20180361146, Dec 20, 2018

Filed:

May 9, 2018

Appl. No.:

15/975678

Inventors:

- Oakland CA, US
Victor Reggie Edgerton - Los Angeles CA, US
Roland R. Roy - Playa Vista CA, US
Daniel C. Lu - Los Angeles CA, US

International Classification:

A61N 1/36
A61K 31/197
A61K 31/00
A61N 1/04
G16H 20/40

Abstract:

In various embodiments, non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries are provided. In some embodiments the methods involve administering transcutaneous electrical spinal cord stimulation (tSCS) to the mammal at a frequency and intensity that induces locomotor activity.

US Patent:

20170157389, Jun 8, 2017

Filed:

Aug 9, 2016

Appl. No.:

15/232623

Inventors:

- Pasadena CA, US
- Oakland CA, US
- Louisville KY, US
Damien Craig Rodger - South Pasadena CA, US
Andy Fong - Los Angeles CA, US
Victor Reggie Edgerton - Los Angeles CA, US
Roland R. Roy - Playa Vista CA, US
Yury Gerasimenko - Los Angeles CA, US
Igor Lavrov - Rancho Palos Verdes CA, US
Susan J. Harkema - Louisville KY, US
Claudia A. Angeli - Louisville KY, US

International Classification:

A61N 1/05

Abstract:

An implantable electrode array assembly configured to apply electrical stimulation to the spinal cord. A substantially electrically nonconductive layer of the device has a first portion positionable alongside the spinal cord that includes a plurality of first openings. The layer has a second portion that includes a plurality of second openings. Electrodes and traces are positioned inside a peripheral portion of a body portion of the device and alongside the layer. At least one of the first openings is adjacent each of the electrodes to provide a pathway through which the electrode may provide electrical stimulation to the spinal cord. At least one of the second openings is adjacent each of the traces to provide a pathway through which the trace may receive electrical stimulation. At least one trace is connected to each electrode and configured to conduct electrical stimulation received by the trace(s) to the electrode.

US Patent:

20170007831, Jan 12, 2017

Filed:

Jul 12, 2016

Appl. No.:

15/208529

Inventors:

- Oakland CA, US
Yury GERASIMENKO - Los Angeles CA, US
Roland R. ROY - Playa Vista CA, US
Daniel C. LU - Rancho Palos Verdes CA, US

International Classification:

A61N 1/36
A61H 1/00

Abstract:

This disclosure provides non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries. In certain embodiments the method involves administering transcutaneous electrical spinal cord stimulation (tSCS) to the mammal at a frequency and intensity that induces the desired locomotor activity.

US Patent:

20160235977, Aug 18, 2016

Filed:

Sep 26, 2014

Appl. No.:

15/025201

Inventors:

- Oakland CA, US
V. Reggie EDGERTON - Los Angeles CA, US
Roland R. ROY - Playa Vista CA, US
Yury P. GERASIMENKO - Los Angeles CA, US

International Classification:

A61N 1/36
A61N 1/05
A61K 31/527

Abstract:

In various embodiments, methods are provided for applying transcutaneous and/or epidural spinal cord stimulation with and without selective pharmaceuticals to restore voluntary control of hand function in tetraplegic subjects.