Stephen M Dewey

US Patent:

6395783, May 28, 2002

Filed:

Oct 23, 2000

Appl. No.:

09/694040

Inventors:

Stephen L. Dewey - Manorville NY
Jonathan D. Brodie - Cos Cob CT

Assignee:

Brookhaven Science Associates, LLC - Upton NY

International Classification:

A61K 31195

US Classification:

514561, 514620, 514638, 514 25

Abstract:

The present invention provides a method for changing addiction-related behavior of a mammal suffering from addiction to phencyclidine (PCP). The method includes administering to the mammal an effective amount of gamma vinylGABA (GVG) or a pharmaceutically acceptable salt thereof, or an enantiomer or a racemic mixture thereof, wherein the effective amount is sufficient to diminish, inhibit or eliminate behavior associated with craving or use of PCP.

US Patent:

6462084, Oct 8, 2002

Filed:

May 14, 2001

Appl. No.:

09/853392

Inventors:

Stephen L. Dewey - Manorville NY
Jonathan D. Brodie - Cos Cob CT

Assignee:

Brookhaven Science Associates, LLC - Upton NY

International Classification:

A61K 31195

US Classification:

514561

Abstract:

The present invention relates to the use of gamma vinyl-GABA (GVG) to treat obsessive-compulsive disorder (OCD) and OCD-related disorders, and to reduce or eliminate behaviors associated with obsessive-compulsive disorder (OCD) and OCD-related disorders.

US Patent:

6541520, Apr 1, 2003

Filed:

Dec 11, 1998

Appl. No.:

09/209952

Inventors:

Stephen L. Dewey - Manorville NY
Jonathan D. Brodie - Cos Cob CT

Assignee:

Brookhaven Science Associates - Upton NY

International Classification:

A01N 3712

US Classification:

514561, 514810, 514811, 514812, 514813, 514291, 514304, 514332, 514343, 514357, 514640, 514641

Abstract:

The present invention provides a highly efficient method for treating substance addiction and for changing addiction-related behavior of a mammal suffering from substance addiction. The method includes administering to a mammal an effective amount of gamma vinylGABA or a pharmaceutically acceptable salt thereof. The present invention also provides a method of treatment of cocaine, morphine, heroin, nicotine, amphetamine, methamphetamine, or ethanol addiction by treating a mammal with an effective amount of gamma vinylGABA or a pharmaceutically acceptable salt thereof. In one embodiment, the method of the present invention includes administering to the mammal an effective amount of a composition which increases central nervous system GABA levels wherein the effective amount is sufficient to diminish, inhibit or eliminate behavior associated with craving or use of drugs of abuse. The composition includes GVG, gabapentin, valproic acid, progabide, gamma-hydroxybutyric acid, fengabine, cetylGABA, topiramate or tiagabine or a pharmaceutically acceptable salt thereof, or an enantiomer or a racemic mixture thereof.

US Patent:

6593367, Jul 15, 2003

Filed:

Jul 28, 1999

Appl. No.:

09/362592

Inventors:

Stephen L. Dewey - Manorville NY
Jonathan D. Brodie - Cos Cob CT

Assignee:

Brookhaven Science Associates - Upton NY

International Classification:

A01N 3712

US Classification:

514561, 514810, 514811, 514812, 514813

Abstract:

The present invention provides a method for changing addiction-related behavior of a mammal suffering from addiction to a combination of abused drugs. The method includes administering to the mammal an effective amount of gamma vinylGABA (GVG) or a pharmaceutically acceptable salt thereof, or an enantiomer or a racemic mixture thereof, wherein the effective amount is sufficient to diminish, inhibit or eliminate behavior associated with craving or use of the combination of abused drugs.

US Patent:

6828349, Dec 7, 2004

Filed:

Nov 9, 1998

Appl. No.:

09/189166

Inventors:

Stephen L. Dewey - Manorville NY
Jonathan D. Brodie - Cos Cob CT

Assignee:

Brookhaven Science Associates - Upton NY

International Classification:

A01N 3712

US Classification:

514561, 514870, 514811, 514812, 514813

Abstract:

The present invention provides a highly efficient method for treating substance addiction and for changing addiction-related behavior of a mammal suffering from substance addiction. The method includes administering to a mammal an effective amount of gamma vinylGABA or a pharmaceutically acceptable salt thereof. The present invention also provides a method of treatment of cocaine, morphine, heroin, nicotine, amphetamine, methamphetamine, or ethanol addiction by treating a mammal with an effective amount of gamma vinylGABA or a pharmaceutically acceptable salt thereof.

US Patent:

6890951, May 10, 2005

Filed:

Aug 20, 2001

Appl. No.:

09/933157

Inventors:

Stephen L. Dewey - Manorville NY, US
Jonathan D. Brodie - Cos Cob CT, US

Assignee:

Brookhaven Science Associates LLC - Upton NY

International Classification:

A61K031/35

US Classification:

514456, 514454, 514455

Abstract:

The present invention relates to the use of a composition that increases central nervous system GABA levels in a mammal, for the treatment of addiction to drugs of abuse and modification of behavior associated with addiction to drugs of abuse in said mammal.

US Patent:

6906099, Jun 14, 2005

Filed:

Feb 2, 2001

Appl. No.:

09/776117

Inventors:

Stephen L. Dewey - Manorville NY, US
Jonathan D. Brodie - Cos Cob CT, US

Assignee:

Brookhaven Science Associates, LLC - Upton NY

International Classification:

A61K031/35
A61K031/34
A61K031/335
A61K031/16
A61K031/18

US Classification:

514454, 514453, 514468, 514463, 514600, 514601

Abstract:

The present invention relates to the use of a composition that increases central nervous system GABA levels in a mammal, for the treatment of addiction to drugs of abuse and modification of behavior associated with addiction to drugs of abuse in said mammal.

US Patent:

6939876, Sep 6, 2005

Filed:

Apr 18, 2002

Appl. No.:

10/124660

Inventors:

Stephen L. Dewey - Manorville NY, US
Jonathan D. Brodie - Cos Cob CT, US

Assignee:

Brookhaven Science Associates, LLC - Upton NY

International Classification:

A61K031/44
A61K031/47
A61K031/445
A61K031/34
A61K031/195

US Classification:

514282, 514310, 514317, 514327, 514468, 514561

Abstract:

The present invention provides a composition for treating pain. The composition includes a pharmaceutically acceptable analgesic and a GABAergic agent, such as gamma vinyl GABA, effective in reducing or eliminating the addictive liability of the analgesic. The invention also includes a method for reducing or eliminating the addictive.

Address:

538 Cypresswood Trce, Spring, TX 77373

VIN:

1FAFP24177G106750

Make:

FORD

Model:

FIVE HUNDRED

Year:

2007