Susan L Mcelroy

US Patent:

63232367, Nov 27, 2001

Filed:

Feb 18, 2000

Appl. No.:

9/506991

Inventors:

Susan McElroy - Cincinnati OH

Assignee:

University of Cincinnati - Cincinnati OH

International Classification:

A61K 31385
A61K 3135
A61K 31335

US Classification:

514439

Abstract:

Impulse Control Disorders (ICD's) are characterized by harmful behaviors performed in response to irresistible impulses. The essential feature of an ICD is the failure to resist an impulse, drive, or temptation and to perform an act that is harmful to the person or to others. The present invention comprises methods for the treatment or prevention of ICD's using a class of sulfamates of the following formula: ##STR1## wherein X is CH. sub. 2 or oxygen, and R. sub. 1, R. sub. 2, R. sub. 3, R. sub. 4 and R. sub. 5 are as herein defined. Further, pharmaceutical compositions containing a compound of formula (I) as well as methods for their use and intermediates form part of the present invention are also disclosed.

US Patent:

20210283126, Sep 16, 2021

Filed:

Jun 2, 2021

Appl. No.:

17/336546

Inventors:

- Morristown NJ, US
Susan McElroy - Mason OH, US
Ron Landbloom - Jersey City NJ, US

Assignee:

Nalpropion Pharmaceuticals LLC - Morristown NJ

International Classification:

A61K 31/485
A61K 31/137
A61K 9/00

Abstract:

Compositions, uses, kits and methods for reducing hinge or compulsive eating are described herein. Methods may include administering an effective combination of a dosage of a bupropion or a pharmaceutically acceptable salt thereof, and a dosage of naltrexone or a pharmaceutically acceptable salt thereof. Methods may include identifying a patient who is overweight or obese and providing an effective combination of bupropion and naltrexone to the patient. Methods may include reducing a number of binge or compulsive eating events. Methods may include reducing severity of binge or compulsive eating events.