Willard C Lew from 1437 Overland Dr, San Mateo, CA 94403, age 62, Phone: (650)5220099

2,4,6-Trisubstituted Pyrido(3,2-D)Pyrimidines Useful For Treating Viral Infections
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US Patent:

8536187, Sep 17, 2013
Filed:

Jul 1, 2009
Appl. No.:

12/996110
Inventors:

Eda Canales - San Mateo CA, US
Lee S. Chong - Newark CA, US
Michael O' Neil Hanrahan Clarke - Redwood City CA, US
Scott E. Lazerwith - San Francisco CA, US
Willard Lew - San Mateo CA, US
Qi Liu - Foster City CA, US
Michael L. Mitchell - Hayward CA, US
William J. Watkins - Saratoga CA, US
Jennifer R. Zhang - Foster City CA, US
Assignee:

Gilead Sciences, Inc. - Foster City CA
International Classification:

A01N 43/90
A61K 31/519
C07D 487/00
US Classification:

51426411, 544279
Abstract:

Pyrido(3,2-d)pyrimidine derivatives represented by the structural formula (Ia): wherein, R, Rand Rare defined herein, pharmaceutical acceptable addition salts, stereochemical isomeric forms, N-oxides, solvates and pro-drugs thereof, for use in the treatment of hepatitis C.

Inhibitors Of Flaviviridae Viruses
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US Patent:

8569302, Oct 29, 2013
Filed:

Jul 19, 2010
Appl. No.:

12/838684
Inventors:

Eda Canales - San Mateo CA, US
Lee S. Chong - Newark CA, US
Michael O'Neil Hanrahan Clarke - Redwood City CA, US
Edward Doerffler - Union City CA, US
Scott E. Lazerwith - San Francisco CA, US
Willard Lew - San Mateo CA, US
Qi Liu - Foster City CA, US
Michael Mertzman - Belmont CA, US
Philip A. Morganelli - Oakland CA, US
William J. Watkins - Saratoga CA, US
Hong Ye - Richmond CA, US
Assignee:

Gilead Sciences, Inc. - Foster City CA
International Classification:

A61K 31/4965
A61K 31/535
A61K 31/505
A61K 31/44
A61K 31/425
A61K 31/41
A61K 31/38
C07D 409/14
C07D 239/02
C07D 413/14
C07D 419/14
C07D 257/04
US Classification:

51425201, 51425505, 5142315, 514274, 51421018, 514336, 514369, 514382, 514444, 514131, 514238, 514316, 514405, 546280, 548187, 548251, 549 60
Abstract:

Provided are compounds of Formula I:.

Novel Compounds And Methods For Synthesis And Therapy
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US Patent:

20040053999, Mar 18, 2004
Filed:

Jul 28, 2003
Appl. No.:

10/628773
Inventors:

Norbert Bischofberger - San Carlos CA, US
Terrence Dahl - Sunnyvale CA, US
Michael Hitchcock - San Mateo CA, US
Choung Kim - San Carlos CA, US
Willard Lew - San Mateo CA, US
Hongtao Liu - Foster City CA, US
Roger Mills - Menlo Park CA, US
Matthew Williams - Foster City CA, US
International Classification:

A61K031/655
A61K031/275
A61K031/215
A61K031/195
US Classification:

514/519000, 514/529000, 514/563000, 514/151000
Abstract:

Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

Novel Compounds And Methods For Synthesis And Therapy
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US Patent:

20050176758, Aug 11, 2005
Filed:

May 24, 1996
Appl. No.:

08/653034
Inventors:

NORBERT W. BISCHOFBERGER - SAN CARLOS CA, US
CHOUNG U. KIM - SAN CARLOS CA, US
WILLARD LEW - SAN MATEO CA, US
HONGTAO LIU - FOSTER CITY CA, US
MATTHEW A. WILLIAMS - FOSTER CITY CA, US
International Classification:

A61K031/47
US Classification:

514310000
Abstract:

Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.