Yong Hong Jiang

US Patent:

20140030727, Jan 30, 2014

Filed:

Jan 22, 2013

Appl. No.:

13/747306

Inventors:

Gerd Pfeifer - Duarte CA, US
Yong Jiang - Decatur GA, US
Runxiang Qiu - Duarte CA, US
Qiang Lu - Duarte CA, US

International Classification:

G01N 33/574
G01N 33/483

US Classification:

435 614

Abstract:

Methods for detecting or diagnosing cancer in a subject are provided herein. Such methods may include, but are not limited to, measuring a test level of 5hmC in a biological sample from the subject; and determining that the subject has a malignant cancer when the test level of 5hmC is lower than that of a control level of 5hmC. Such methods may further include a step of measuring a test level of Ki67 in the biological sample and determining that the subject has a malignant cancer when the test level of Ki67 is higher than that of a control level of Ki67.