- Wilmington DE, US Jeffrey Yang - Wilmington DE, US Yong Li - Wilmington DE, US Le Zhao - Wilmington DE, US Chunhong He - Wilmington DE, US Chunyin Marshall Law - Wilmington DE, US Xiaozhao Wang - Mt. Laurel NJ, US Wenqing Yao - Wilmington DE, US
International Classification:
C07D 471/04 A61P 35/00
Abstract:
Disclosed are compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.
- Wilmington DE, US Wenyu Zhu - Wilmington DE, US Jeffrey Yang - Wilmington DE, US Alexander Sokolsky - Wilmington DE, US Chunhong He - Wilmington DE, US Zhenwu Li - Wilmington DE, US Chao Qi - Wilmington DE, US Yong Li - Wilmington DE, US Pei Gan - Wilmington DE, US Peter Carlsen - Wilmington DE, US Gia Hoang - Wilmington DE, US Chenyin Marshall Law - Wilmington DE, US Fenglei Zhang - Berwyn PA, US Padmaja Polam - Kennett Square PA, US Le Zhao - Wilmington DE, US Liangxing Wu - Wilmington DE, US Wenqing Yao - Wilmington DE, US
International Classification:
C07D 471/04 A61P 35/00 C07D 519/00 C07D 471/14
Abstract:
Disclosed are compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.
Fused Pyrazine Derivatives As A2A / A2B Inhibitors
- Wilmington DE, US Peter Niels Carlsen - Claymont DE, US Pei Gan - Claymont DE, US Gia Hoang - Wilmington DE, US Yong Li - Newark DE, US Chao Qi - Newark DE, US Liangxing Wu - Wilmington DE, US Wenqing Yao - Chadds Ford PA, US Zhiyong Yu - Wilmington DE, US Wenyu Zhu - Media PA, US
International Classification:
C07D 487/04 C07D 519/00
Abstract:
This application relates to compounds of Formula (I):or pharmaceutically acceptable salts thereof, which modulate the activity of adenosine receptors, such as subtypes A2A and A2B receptors, and are useful in the treatment of diseases related to the activity of adenosine receptors including, for example, cancer, inflammatory diseases, cardiovascular diseases, and neurodegenerative diseases.
Dr. Li graduated from the Shanghai Med Univ, Shanghai First Med Univ, Shanghai, China in 1991. He works in Oshkosh, WI and 2 other locations and specializes in Psychiatry. Dr. Li is affiliated with Theda Care Regional Medical Center and Thedacare Regional Medical Center Appleton.
Dr. Li graduated from the Shanghai Med Univ, Shanghai First Med Univ, Shanghai, China in 1968. He works in Pearland, TX and specializes in Family Medicine and Acupuncturist. Dr. Li is affiliated with Baylor St Lukes Medical Center and The Womans Hospital Of Texas.
Counseling & Psychological Services At The University Of Pennsylvania 3624 Market St STE 1W, Philadelphia, PA 19104 (215)8987021 (phone), (215)5738966 (fax)
Education:
Medical School Beijing Med Univ, Beijing City, Beijing, China Graduated: 1986
St GallenPast: Associate Director of Strategic Investment Department at Huashang Media Group Co Ltd... mature, self-motivated, and ambitious;
in-depth knowledge & understanding in China’s society and economy;
connections to Chinese entrepreneurs, capital... mature, self-motivated, and ambitious;
in-depth knowledge & understanding in China’s society and economy;
connections to Chinese entrepreneurs, capital market, and media/publishing industry;
experience in business development and making investment in media industry;
working experience in US...