Allen T Nguyen

US Patent:

20030158212, Aug 21, 2003

Filed:

Oct 24, 2002

Appl. No.:

10/280138

Inventors:

Teri Melese - Cupertino CA, US
Edward Perkins - Duluth MN, US
Allen Nguyen - Santa Clara CA, US
Dongxu Sun - Cupertino CA, US

International Classification:

A61K031/519
C07D498/14

US Classification:

514/257000, 544/247000

Abstract:

Compounds of formula 1 are effective modulators of PI3 kinase: wherein X is CRR, O, NR(where Rand Rare each independently H, lower alkyl, lower alkoxy, or halo, and Ris H or lower alkyl); or single bond; Ris H, lower alkyl, aryl, aralkyl; Ris H, lower alkyl, aryl, aralkyl, heteroaryl, heteroaryl-alkyl, lower alkoxy, amino, lower alkylamino, lower acylamino, arylamino, arylacyl-amino, heteroaryl-amino, heteroaryl-acyl amino, thio, lower alkylthio, arylthio, or aralkyl-thio, where aryl and heteroaryl are substituted with 0-3 substituents selected from the group consisting of halo, trihalomethyl, hydroxy, lower alkyl and lower alkoxy; R, R, R, R, R, and Rare each independently H, lower alkyl, lower alkoxy, or halo; or a pharmaceutically acceptable salt or ester thereof.

US Patent:

20030149074, Aug 7, 2003

Filed:

Oct 24, 2002

Appl. No.:

10/280116

Inventors:

Teri Melese - Cupertino CA, US
Edward Perkins - Duluth MN, US
Allen Nguyen - Santa Clara CA, US
Dongxu Sun - Cupertino CA, US

International Classification:

A61K031/4709
A61K031/4706
C07D215/36

US Classification:

514/312000, 546/157000

Abstract:

Compounds of formula are effective modulators of PI3 kinase: wherein Ris H, hydroxy, amino, lower alkyl, or trihalomethyl; Ris amino, lower alkylamino, lower acylamino, arylamino, arylacyl-amino, heteroaryl-amino, heteroaryl-acyl amino, where aryl and heteroaryl are substituted with 0-3 substituents selected from the group consisting of halo, trihalomethyl, hydroxy, lower alkyl and lower alkoxy, or a substituent of the form —(CH)—C( X)—R, where n is 0-3 inclusive and X is O or NR, where Ris H, lower alkyl, or R, and Rtogether form —CH N—X—where X is CH, NH, O, or S, and Ris H, lower alkyl, lower alkoxy, aryl, aralkyl, or —(CH)CRRR, where m is 0-3 inclusive, and R, R, and Rare each independently H, lower alkyl, aryl, aralkyl, hydroxy, lower alkoxy, aryloxy, aralkoxy, amino, lower alkyl-amino, arylamino, aralkylamino, heteroaryl amino, or heteroaralkyl amino, where aryl and heteroaryl are substituted with 0-3 substituents selected from the group consisting of halo, hydroxy, and lower alkyl; Ris H or lower alkyl; and R, R, R, Rare each independently H, halo, hydroxy, amino, nitro, lower alkyl, or lower alkoxy; and pharmaceutically acceptable salts thereof.

US Patent:

20210295224, Sep 23, 2021

Filed:

Mar 23, 2020

Appl. No.:

16/827305

Inventors:

- San Francisco CA, US
Nir Even Chen - Redwood City CA, US
John Stevens Markevitch - Palo Alto CA, US
Mohammad Ali Motie Share - San Francisco CA, US
Allen Lamson Nguyen - Long Island City NY, US
Lily Sierra - San Francisco CA, US

International Classification:

G06Q 10/06
G06N 5/04

Abstract:

The present disclosure relates to systems, non-transitory computer-readable media, and methods for intelligently pre-dispatching candidate provider devices to a geographic area by utilizing a pre-dispatch model accounting for forecasted transportation requests. For example, the disclosed systems can determine how many candidate provider devices to pre-dispatch to a geographic area based on a variety of inputs, including a projected requestor device queue, a projected provider device queue, and/or a queue capacity. In particular, the disclosed systems can utilize a look-ahead model and a look-behind model to compare a queue capacity with projected provider device queues corresponding to estimated times of arrival for one or more candidate provider devices. If the projected provider device queues comport with the queue capacity according to both the look-ahead model and the look-behind model, the disclosed systems can proceed with pre-dispatching the candidate provider device to the geographic area.