Catherine W Cabrera

US Patent:

7141429, Nov 28, 2006

Filed:

Oct 9, 2002

Appl. No.:

10/268620

Inventors:

Matthew S. Munson - Gaithersburg MD, US
Catherine R. Cabrera - Cambridge MA, US
Paul Yager - Seattle WA, US
Anson Hatch - Seattle WA, US
Andrew Kamholz - Seattle WA, US

Assignee:

University of Washington - Seattle WA

International Classification:

G01N 35/08
B01D 17/00

US Classification:

436 53, 436 52, 210511

Abstract:

This invention provides methods for using liquid junction potentials to control the transport of charged particles in fluid streams that are in laminar flow within microfluidic channels. Applications of the methods of this invention include sample preconditioning (removal of interfering substances), electrophoretic separation (fractionation) of charged particles, enhanced or delayed mixing of charged particles across a fluid interface relative to diffusion only, focusing charged particles in a fluid stream in one or two dimensions, and concentration of charged reactants at a fluid interface.

US Patent:

20060196771, Sep 7, 2006

Filed:

May 22, 2006

Appl. No.:

11/419717

Inventors:

Matthew Munson - Gaithersburg MD, US
Catherine Cabrera - Cambridge MA, US
Paul Yager - Seattle WA, US
Anson Hatch - Seattle WA, US
Andrew Kamholz - Seattle WA, US

Assignee:

University of Washington - Seattle WA

International Classification:

C07K 1/26
G01N 27/447

US Classification:

204451000, 204601000

Abstract:

This invention provides methods for using liquid junction potentials to control the transport of charged particles in fluid streams that are in laminar flow within microfluidic channels. Applications of the methods of this invention include sample preconditioning (removal of interfering substances), electrophoretic separation (fractionation) of charged particles, enhanced or delayed mixing of charged particles across a fluid interface relative to diffusion only, focusing charged particles in a fluid stream in one or two dimensions, and concentration of charged reactants at a fluid interface.