Chao H Lin from San Gabriel, CA, age 83

Wikipedia

Lin Chao

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Professor Lin Chao is a Chinese Brazilian American evolutionary biologist and geneticist. Professor ...

Medicine Doctors

Chao I Lin, Brea CA

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Specialties:

Allergist

Address:

340 W Central Ave, Brea, CA 92821
505 S Main St, Orange, CA 92868

Board certifications:

American Board of Allergy and Immunology Certification in Allergy and Immunology

Us Patents

Crystals Of Hepatitis C Virus Helicase Or Fragments Thereof Comprising A Helicase Binding Pocket
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US Patent:

7438920, Oct 21, 2008
Filed:

Apr 30, 1999
Appl. No.:

09/303216
Inventors:

Joseph L. Kim - Natick MA, US
Kurt Morgenstern - Derry NH, US
Paul Caron - Malden MA, US
Chao Lin - Brookline MA, US
Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:

A61K 39/29
A61K 38/43
G01N 33/53
C12N 9/00
US Classification:

4242281, 435 71, 435183, 514 2, 514 12
Abstract:

The invention relates to the X-ray crystal structure of the hepatitis C virus helicase domain. More specifically, the invention relates to crystallized complexes of HCV helicase and an oligonucleotide, to crystallizable compositions of HCV helicase and an oligonucleotide and to methods of crystallizing an HCV helicase-oligonucleotide complex. The invention further relates to a computer programmed with the structure coordinates of the HCV helicase oligonucleotide binding pocket or the HCV helicase nucleotide triphosphate pocket wherein said computer is capable of displaying a three-dimensional representation of that binding pocket.

Hcv Ns3-Ns4A Protease Resistance Mutants
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US Patent:

7494660, Feb 24, 2009
Filed:

Oct 27, 2004
Appl. No.:

10/974558
Inventors:

Chao Lin - Winchester MA, US
Kai Lin - Waltham MA, US
Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:

C12N 7/00
C07H 21/04
US Classification:

4242181, 536 231
Abstract:

The present invention is directed to mutants of HCV NS3/4A protease. More particularly, the present invention identifies mutant of HCV NS3/4A protease that are resistant to drug treatment.

Hepatitis C Virus Variants
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US Patent:

7705138, Apr 27, 2010
Filed:

Nov 13, 2006
Appl. No.:

11/599162
Inventors:

Chao Lin - Winchester MA, US
Tara Kieffer - Brookline MA, US
Christoph Sarrazin - Hamburg, DE
Ann Kwong - Cambridge MA, US
Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:

C12N 15/57
C12N 15/51
C12N 15/74
C12N 15/79
C12N 9/50
C12P 19/34
US Classification:

536 232, 435 691, 435 9121, 435219, 4352523, 4353201, 536 231, 536 2372
Abstract:

The present invention relates to HCV variants, particularly variants that are resistant to a protease inhibitors such as VX-950. Also provided are methods and compositions related to the HCV variants. Further provided are methods of isolating, identifying, and characterizing multiple viral variants from a patient.

Hcv Ns3-Ns4 Protease Resistance Mutants
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US Patent:

7884199, Feb 8, 2011
Filed:

Nov 17, 2008
Appl. No.:

12/272425
Inventors:

Chao Lin - Winchester MA, US
Kai Lin - Waltham MA, US
Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:

C07H 23/00
C12N 7/00
C12Q 1/70
US Classification:

536 2371, 4353201, 435 691, 4352351, 435 6
Abstract:

The present invention is directed to mutants of HCV NS3/4A protease. More particularly, the present invention identifies mutant of HCV NS3/4A protease that are resistant to drug treatment.

Combination Therapy For The Treatment Of Hcv Infection
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US Patent:

8258116, Sep 4, 2012
Filed:

May 5, 2008
Appl. No.:

12/598802
Inventors:

Ann Kwong - Cambridge MA, US
Nagraj Mani - Natick MA, US
Yi Zhou - Lexington MA, US
Chao Lin - Winchester MA, US
Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:

A01N 43/04
A61K 31/70
US Classification:

514 49, 514 43, 514 50, 514 51
Abstract:

The present invention relates to therapeutic combinations comprising a protease inhibitor and a polymerase inhibitor for the treatment of HCV. The present invention also relates to therapeutic combinations comprising VX-950 and a polymerase inhibitor. Also within the scope of the invention are methods using the therapeutic combinations of the present invention for treating HCV infection or alleviating one or more symptoms thereof in a patient. The present invention also provides kits comprising the combinations of the present invention.

Hepatitis C Virus Variants
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US Patent:

8501450, Aug 6, 2013
Filed:

Mar 5, 2010
Appl. No.:

12/718340
Inventors:

Chao Lin - Winchester MA, US
Tara Kieffer - Brookline MA, US
Christoph Sarrazin - Saarland, DE
Ann Kwong - Cambridge MA, US
Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:

C12N 9/50
C12N 15/51
C12N 15/57
C12N 15/74
C12N 15/79
C12P 19/34
US Classification:

435219, 4352523, 4353201, 536 232, 536 2372
Abstract:

The present invention relates to HCV variants, particularly variants that are resistant to a protease inhibitors such as VX-950. Also provided are methods and compositions related to the HCV variants. Further provided are methods of isolating, identifying, and characterizing multiple viral variants from a patient.

Crystallizable Compositions Comprising A Hepatitis C Virus Ns3 Protease Domain/Ns4A Complex
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US Patent:

20020042046, Apr 11, 2002
Filed:

Sep 14, 2001
Appl. No.:

09/952975
Inventors:

Joseph Kim - Natick MA, US
Kurt Morgenstern - Derry NH, US
Chao Lin - Cambridge MA, US
Ted Fox - Maynard MA, US
John Thomson - Belmont MA, US
Assignee:

Vertex Pharmaceuticals, Incorporated
International Classification:

C12Q001/70
C12N009/50
C12N007/00
US Classification:

435/005000, 435/219000, 435/235100
Abstract:

The present invention relates to compositions and crystals of a hepatitis C virus protease in complex with its viral cofactor. This invention also relates to methods of using the structure coordinates of hepatitis C virus protease in complex with a synthetic NS4A to solve the structure of similar or homologous proteins or protein complexes.

Quantitative Assay For Nucleic Acids
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US Patent:

20020187488, Dec 12, 2002
Filed:

Jan 30, 2002
Appl. No.:

10/060738
Inventors:

Chao Lin - Brookline MA, US
Anne Kwong - Cambridge MA, US
International Classification:

C12Q001/68
C12P019/34
US Classification:

435/006000, 435/091200
Abstract:

The present invention provides a method of accurately assaying the amount of nucleic acids in a biological source. According to another embodiment, the present invention provides a method of accurately assaying HCV in a biological source. The present invention also provides a method of simultaneously screening the effect of a plurality of compounds on the replication of a whole or part of a genome of a biological source. The present invention provides a method of simultaneously screening the effect of a plurality of compounds on the replication of the whole or part of the HCV genome in a biological source.

Name / Title

Company / Classification

Phones & Addresses

Chao H Lin
Manager

The Stone House Shoppes
Eating Places

822 S Robertson Blvd, Los Angeles, CA 90035

Chao Cheng Lin
President

La Ni's Food Service, Inc

10460 Rosecrans Ave, Bellflower, CA 90706

Chao Lin
President

Xundaex, Inc

1045 E Vly Blvd, San Gabriel, CA 91776
137 S 8 Ave, Whittier, CA 91746

Chao I. Lin
President

Galant & Lin, M.D.'s, Inc

505 S Main St, Orange, CA 92868

Chao Chung Lin
President

Pacific Carpet & Home Interiors Inc
Ret Floor Covering

200 Technology Dr, Irvine, CA 92618

Chao Jen Lin
President

CORNER PRODUCTS COMPANY
Whol Electronic Parts/Equipment Whol Computers/Peripherals · Mfg Computer Peripheral Equipment

17110 Armstrong Ave, Irvine, CA 92614
Westminster, CA 92683
(949)2315000, (714)8988889, (714)2315019, (800)8768889

Chao Lin
Partner

Alamo Inn & Suites
Motel

1140 W Katella Ave, Anaheim, CA 92802
(714)6358070

Chao Lin
Vice-President

Argo Metal Corporation
Whol Scrap/Waste Material Whol Appliances/TV/Radio

713 W Duarte Rd, Arcadia, CA 91007
(626)4470608

Resumes

Chao Xian Jessica Lin

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Position:

Student Assistant at Keck Graduate Institute

Location:

Greater Los Angeles Area

Industry:

Biotechnology

Work:

Keck Graduate Institute
Student Assistant
Baxter Healthcare Jun 2009 - Aug 2009
Intern
Baxter BioScience 2009 - 2009
Intern

Education:

Keck Graduate Institute of Applied Life Sciences 2009 - 2011
Master of Bioscience, Business of Bioscience, Medical Devices & Diagnostics University of California, Los Angeles 2004 - 2009
BA, BS, Economics, Microbiology, Immunology, & Molecular Genetics

Honor & Awards:

W.M. Keck Graduate Fellowship, 2009-2011, UCLA Undergraduate Research Fellows Scholarship, 2006

Concept Artist

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Location:

Greater Los Angeles Area

Industry:

Entertainment

Work:

Saltire Entertainment LLC Feb 2009 - Apr 2009
Contracted Concept Artist
Radical Comics Feb 2009 - Mar 2009
Production Artist
Black Mana Studios Feb 2009 - Mar 2009
Contracted Concept and Matte Painting Artist
Fleishman-Hillard Jan 2009 - Feb 2009
Art Direction, Level Design.
Creo Ludus Entertainment, LLC Dec 2008 - Feb 2009
Contract Concept Artist

Education:

Art Center College of Design 2004 - 2008
The Gnomon School of Visual Effect 2006 - 2006

Electrical Engineer, Master's In Electrical Engineering Candidate, Case Western Reserve University

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Position:

Research Assistant at Case Western Reserve University: Control & Energy Systems Center Lab Cleveland, Ohio

Location:

Cleveland, Ohio

Industry:

Electrical/Electronic Manufacturing

Work:

Case Western Reserve University: Control & Energy Systems Center Lab Cleveland, Ohio - Cleveland/Akron, Ohio Area since Aug 2012
Research Assistant

Education:

Case Western Reserve University 2012 - 2013
Master of Engineering (MEng), Electrical and Electronics Engineering Abilene Christian University, Abilene, Texas 2009 - 2011
Bachelors of Science Engineering, Engineering Management South China University of Technology 2006 - 2009
Bachelor of Engineering (B.Eng.), Electrical and Electronics Engineering

Languages:

English
Cantonese
Mandarin

Chao Lin

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Location:

United States

Chao Lin Quincy, MA

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Work:

University of Massachusetts Boston

Jul 2010 to 2000
Human Resource Payroll Clerk W Boston Hotels Human Resource
Boston, MA
Aug 2009 to Aug 2009
Temporary Career Fair Interpreter

Education:

University of Massachusetts Boston
Boston, MA
Sep 2008 to 2000
Bachelor of Science in Management

Chao Lin Los Angeles, CA

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Work:

Nonlinear Ion Dynamics
Panorama City, CA
Jun 2014 to Oct 2014
Research Engineer USC project
Los Angeles, CA
Mar 2013 to May 2013
Finite Element Analysis Project HUST Graduate Project
Wuhan, China
Mar 2012 to Jun 2012
Numerical Simulation Design Sichuan Air Separation Group
Sichuan, China
Jul 2011 to Sep 2011
Assistant Engineer Internship

Education:

University of Southern California
Los Angeles, CA
2012 to 2014
Master of Science in Mechanical Engineering Huazhong University of Science and Technology
Wuhan, China
2008 to 2012
Bachelor of Science in Energy and Power Engineering

Skills:

ANSYS, SolidWorks, Abaqus, AutoCAD, MATLAB, MS Office, Programming C, Finite Element Analysis, Computational Fluid Dynamics, Mechanical Engineering Sciences, HVAC system, Computer Aided Design and Manufacturing, Japanese, Chinese-Mandarin, Java, C++, Python