Dan Li

US Patent:

20130331919, Dec 12, 2013

Filed:

Aug 12, 2013

Appl. No.:

13/964807

Inventors:

Haresh G. Sachanandani - Culver City CA, US
Dan Li - Shoreview MN, US
Bin Mi - Plymouth MN, US

Assignee:

Cardiac Pacemakers, Inc. - St. Paul MN

International Classification:

A61N 1/05

US Classification:

607119

Abstract:

Various implantable medical device embodiments stimulate an autonomic neural target from within a pulmonary artery, and comprise at least one electrode, a power supply, a neural stimulator connected to the power supply, and an anchor structure. The neural stimulator is configured to generate a neural stimulation signal for delivery to the neural stimulation target through the at least one electrode. The anchor structure is configured to chronically and securely implant the neural stimulator, the power supply and the at least one electrode within the pulmonary artery. The anchor structure, the neural stimulator, the power supply and the at least one electrode are configured to be implanted through a pulmonary valve into the pulmonary artery. In various embodiments, the neural stimulator is configured to be operational to implement a neural stimulation protocol when chronically implanted within the pulmonary artery without a wired connection through the pulmonary valve.

US Patent:

20150297760, Oct 22, 2015

Filed:

Mar 15, 2013

Appl. No.:

14/438863

Inventors:

Peter S. CONTI - Pasadena CA, US
Zibo LI - , US
Shuanglong LIU - , US
Dan LI - Los Angeles CA, US

Assignee:

University of Southern California - Los Angeles CA

International Classification:

A61K 51/04
A61B 6/03
A61K 49/00
A61B 5/00

Abstract:

This invention provides a class of dual mode imaging tracer capable of acting both as a fluorescent imaging tracer and a positron emission tomography imaging tracer. Tracers in accordance with this invention generally have a fluorescent core with a boron-fluoride element embedded therein. Exemplary embodiments of the tracer include F-labeled BODIPY compounds and derivative thereof. Also provided are tracer kits containing a sterile formulation of a BODIPY dye either in a radio-labeled or pre-labeled state, and methods for imaging heart perfusion using the F-labeled dual mode tracers.