Dan J Li

US Patent:

7279184, Oct 9, 2007

Filed:

Oct 25, 2004

Appl. No.:

10/972986

Inventors:

Robert T. Gow - Naples FL, US
George W. Sypert - Naples FL, US
John Pierce - Thousand Oaks CA, US
Dan Li - Naples FL, US
Xun Yan - Naples FL, US
Rodger M. Marentis - Macungie PA, US

Assignee:

HerbalScience, LLC - Naples FL

International Classification:

A61K 36/00

US Classification:

424725, 426427

Abstract:

The present invention comprises methods for making compositions derived from species, particularly , having lowered caffeine and tannin concentrations, compositions made by such methods, oral delivery formulations, and methods of use of such compositions. In particular, the present invention comprises methods for making maté compositions that have a predetermined characeteristic, such as a lowered amount of caffeine, elevated amounts of caffeoyls, and/or lowered amounts of tannin compounds compared to the native maté plant materials. Further, the invention comprises methods of additional processing steps to produce compositions having a predetermined alkaloid ratio or profiles to meet particular considerations for final products. The compositions of the present invention may be processed for specific uses such as tablets or other oral delivery vehicles. These compositions may be used in methods for treatment of physiological and medical conditions.

US Patent:

7294353, Nov 13, 2007

Filed:

Oct 21, 2004

Appl. No.:

10/970017

Inventors:

Robert T. Gow - Naples FL, US
George W. Sypert - Naples FL, US
John Pierce - Thousand Oaks CA, US
Dan Li - Naples FL, US
Xun Yan - Naples FL, US
Rodger M. Marentis - Macungie PA, US

Assignee:

HerbalScience, LLC - Naples FL

International Classification:

A61K 36/00

US Classification:

424725

Abstract:

The present invention comprises methods for making compositions derived from species, particularly , having lowered caffeine and tannin concentrations, compositions made by such methods, oral delivery formulations, and methods of use of such compositions. In particular, the present invention comprises methods for making maté compositions that have a predetermined characeteristic, such as a lowered amount of caffeine, elevated amounts of caffeoyls, and/or lowered amounts of tannin compounds compared to the native maté plant materials. Further, the invention comprises methods of additional processing steps tp produce compositions having a predetermined alkaloid ratio or profiles to meet particular considerations for final products. The compositions of the present invention may be processed for specific uses such as tablets or other oral delivery vehicles. These compositions may be used in methods for treatment of physiological and medical conditions.

US Patent:

20050181374, Aug 18, 2005

Filed:

Jan 5, 2004

Appl. No.:

10/752079

Inventors:

Scott Friedman - Scarsdale NY, US
Dan Li - New York NY, US
Goutham Narla - New York NY, US
John Martignetti - Chappaqua NY, US
Karen Heath - Madrid, ES

Assignee:

Mount Sinai School of Medicine of New York University - New York NY

International Classification:

C12Q001/68
G01N033/53
G01N033/567

US Classification:

435006000, 435007200

Abstract:

The present invention relates to identification of tumor suppressor activity of a protein, KLF6 (KLF6), and to related diagnostic and therapeutic compositions and methods. The discovery of this tumor suppressor activity provides screening targets as well, particularly screening for compounds that overcome gene inactivation or alteration.

US Patent:

20110059899, Mar 10, 2011

Filed:

Apr 28, 2010

Appl. No.:

12/769595

Inventors:

Scott Friedman - Scarsdale NY, US
Dan Li - Arlington MA, US
Goutham Narla - New Rochelle NY, US
John Martignetti - Chappaqua NY, US
Karen Heath - Madrid, ES

Assignee:

Mount Sinai School of Medicine of New York University - New York NY

International Classification:

A61K 38/17
A61K 31/7088
A61P 35/00
C12Q 1/68
G01N 33/53
C12Q 1/48
C12Q 1/28
C12N 5/02
C12N 15/63

US Classification:

514 193, 514 44 R, 435 6, 435 71, 435 15, 435 28, 435375, 4353201

Abstract:

The present invention relates to identification of tumor suppressor activity of a protein, KLF6 (KLF6), and to related diagnostic and therapeutic compositions and methods. The discovery of this tumor suppressor activity provides screening targets as well, particularly screening for compounds that overcome gene inactivation or alteration.

US Patent:

20180228853, Aug 16, 2018

Filed:

Aug 31, 2016

Appl. No.:

15/755960

Inventors:

- Tucson AZ, US
John M. Williams - Bonita Springs FL, US
Dan LI - Fort Myers FL, US

International Classification:

A61K 36/185
A61P 31/16
A61K 31/215
A61K 31/351
A61K 31/13
A61K 31/19
A61P 31/14

Abstract:

The present invention relates generally to compositions and methods of use that include compounds that treat and prevent viral infections.