Marcel Patek - Tucson AZ, US Anil Nair - Tucson AZ, US Augustin Hittinger - Igny, FR Conception Nemecek - Thiais, FR Daniel Bond - Tucson AZ, US Greg Harlow - Boulder CO, US Herve Bouchard - Thiais, FR Jacques Mauger - Tucson AZ, US Jean-Luc Malleron - Marcoussis, FR Mark Palermo - Peapack NJ, US Fahad Al-Obeidi - Tucson AZ, US Thomas Faitg - Exton PA, US Hartmut Strobel - Liederbach, DE Sven Ruf - Floersheim, DE Kurt Ritter - Frankfurt Am Main, DE Youssef El-Ahmad - Creteil, FR Dominique Lesuisse - Montreuil, FR
Assignee:
AVENTIS PHARMA S.A. - Antony
International Classification:
A61K031/551 A61K031/513 C 07D 4 9/02 C 07D 4 5/02
US Classification:
514/218000, 514/269000, 540/575000, 544/310000
Abstract:
The present invention relates to a cyclic urea compound of formula I: as defined herein. The invention is also directed to the process for its preparation, pharmaceutical composition comprising it and its pharmaceutical use, as an inhibitor on a protein kinase. Thus, it is useful for preventing or treating a physiological disorder capable of being modulated by inhibiting the activity of a protein kinase, such as a solid tumor.
Isbn (Books And Publications)
Trade or Aid?: Official Export Credit Agencies and the Economic Development of Eastern Europe and the Soviet Union
Seventh Day Adventist Elementary School Coquille OR 1986-1989, Portland Adventist School Gresham OR 1986-1989, Challenger Elementary School Everett WA 1989-1990, Emerson Elementary School Everett WA 1990-1992, Evergreen Middle School Everett WA 1992-1994, Eisenhower Middle School Everett WA 1994-1995, Sno-Isle Vocational Skills Center High School Everett WA 1997-1999
Community:
Amber Perkins, Jenny Black, Greg Kuge, Robin Hedden, Lisa Collins, Vanessa Prieto, Robert Wolverton, David Nelson, Samantha Shelton, Scott Parkere