Daniel C Pevear

US Patent:

6495580, Dec 17, 2002

Filed:

Oct 18, 1999

Appl. No.:

09/254690

Inventors:

Theodore J. Nitz - Pottstown PA
Daniel C. Pevear - Harleysville PA

Assignee:

ViroPharma Incorporated - Exton PA

International Classification:

C07D20730

US Classification:

514365, 514378, 514381, 514383, 514348, 548203, 548247, 548251, 548252, 5482652, 5483361

Abstract:

Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections.

US Patent:

6541472, Apr 1, 2003

Filed:

Apr 12, 2000

Appl. No.:

09/547607

Inventors:

Daniel C. Pevear - Harleysville PA
Theodore J. Nitz - Pottstown PA
Martin Seipel - Malvern PA

Assignee:

ViroPharma Incorporated - Exton PA

International Classification:

C07D48704

US Classification:

514243, 51421705, 544184, 540599

Abstract:

Triazinoindole derivatives are useful in the prophylaxis and treatment of pestivirus infections and diseases associated with pestivirus infections.

US Patent:

8119672, Feb 21, 2012

Filed:

Aug 11, 2003

Appl. No.:

10/524313

Inventors:

David J. Rys - Phialdelphia PA, US
Theodore J. Nitz - Pottstown PA, US
Janet A Gaboury - Blue Bell PA, US
Christopher J. Burns - Malvern PA, US
Daniel C. Pevear - Harleysville PA, US
Thomas A. Lessen - Langhorne PA, US
Torsten Herbertz - Honey Brook PA, US

Assignee:

Microdose Therapeutx, Inc. - Monmouth Junction NJ

International Classification:

A61K 31/41
C07D 43/02

US Classification:

514381, 548282

Abstract:

Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections.

US Patent:

8202896, Jun 19, 2012

Filed:

Aug 11, 2003

Appl. No.:

10/524162

Inventors:

Theodore J. Nitz - Pottstown PA, US
Janet A. Gaboury - Blue Bell PA, US
Christopher J. Burns - Malvern PA, US
Sylvie Laguerre - Exton PA, US
Daniel C. Pevear - Harleysville PA, US
Thomas A. Lessen - Langhorne PA, US
David J. Rys - Philadelphia PA, US

Assignee:

Microdose Therapeutx, Inc. - Monmouth Junction NJ

International Classification:

A61K 31/41
C07D 257/06

US Classification:

514381, 548251

Abstract:

Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection.

US Patent:

8575205, Nov 5, 2013

Filed:

Mar 22, 2012

Appl. No.:

13/427664

Inventors:

Theodore J. Nitz - Pottstown PA, US
Janet A. Gaboury - Blue Bell PA, US
Christopher J. Burns - Malvern PA, US
Sylvie Laguerre - Exton PA, US
Daniel C. Pevear - Harleysville PA, US
Thomas A. Lessen - Langhorne PA, US
David J. Rys - Philadelphia PA, US

Assignee:

Microdose Therapeutx, Inc. - Monmouth Junction NJ

International Classification:

A61K 31/41
C07D 257/06

US Classification:

514381, 548251

Abstract:

Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection.

US Patent:

20020081574, Jun 27, 2002

Filed:

Dec 7, 2001

Appl. No.:

10/010860

Inventors:

Marc Collett - Collegeville PA, US
Daniel Pevear - Harleysville PA, US
James Groarke - Phoenixville PA, US
Dorothy Young - Collegeville PA, US

International Classification:

C12Q001/70
C12N009/22
C12N015/86
C12P021/02

US Classification:

435/005000, 435/069100, 435/199000, 435/456000

Abstract:

Assay methods are disclosed having utility in the identification of therapeutic agents effective against human hepatitis C virus and related viruses. NS3 protein derived from these viruses, representing a native and authentic version of the complete protein sequence, is used in the assay methods of the invention, which enables identification and development of anti-viral agents exhibiting inhibition of the protein's NTPase and RNA helicase activities.

US Patent:

20030092685, May 15, 2003

Filed:

Oct 25, 2002

Appl. No.:

10/280528

Inventors:

Theodore Nitz - Pottstown PA, US
Daniel Pevear - Harleysville PA, US

International Classification:

A61K031/65
A61K031/55
A61K031/553
A61K031/554
A61K031/426
A61K031/4196
A61K031/41

US Classification:

514/152000, 514/211010, 514/381000, 514/383000, 514/365000, 514/380000, 514/340000, 546/268100, 548/202000, 548/251000, 548/264800

Abstract:

Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections.

US Patent:

20030176431, Sep 18, 2003

Filed:

Feb 5, 2003

Appl. No.:

10/359400

Inventors:

Daniel Pevear - Harleysville PA, US
Theodore Nitz - Pottstown PA, US
Martin Seipel - Malvern PA, US

International Classification:

A61K031/5377
A61K031/55
A61K031/53
C07D487/02

US Classification:

514/232800, 514/243000, 544/112000, 544/184000, 514/217050, 540/599000

Abstract:

Triazinoindole derivatives are useful in the prophylaxis and treatment of pestivirus infections and diseases associated with pestivirus infections.