John R. Desjarlais - Pasadena CA, US Paul Michael Steed - Chapel Hill NC, US Jonathan Zalevsky - Riverside CA, US David Edmund Szymkowski - Monrovia CA, US David F. Carmichael - Monrovia CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
A61K 38/19 A61K 38/00 C07K 38/00
US Classification:
424 851, 514 2, 530350
Abstract:
The invention relates to a pharmaceutical composition comprising a variant TNF-α protein that inhibits the activity of soluble TNF-α while substantially maintaining the activity of transmembrane TNF-α a buffer and a tonicity agent wherein said composition has a pH from approximately 5. 0 to 8.
Gregory Alan Lazar - Arcadia CA, US John R. Desjarlais - Pasadena CA, US Philip W. Hammond - Sierra Madre CA, US David F. Carmichael - Monrovia CA, US Bao-lu Chen - San Ramon CA, US Seung Y. Chu - Upland CA, US Sher Bahadur Karki - Pasadena CA, US Lori Kunkel - San Francisco CA, US
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcgR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
Fc Variants With Optimized Fc Receptor Binding Properties
John Desjarlais - Pasadena CA, US Sher Karki - Pasadena CA, US Gregory Lazar - Arcadia CA, US John Richards - Monrovia CA, US Gregory Moore - Pasadena CA, US David Carmichael - Monrovia CA, US
International Classification:
A61K 39/395 C07K 16/28
US Classification:
424144100, 530388220
Abstract:
The present invention relates to Fc variants with optimized Fc receptor binding properties, methods for their generation, Fc polypeptides comprising Fc variants with optimized Fc receptor binding properties, and methods for using Fc variants with optimized Fc receptor binding properties.
Gregory Lazar - Arcadia CA, US John Desjarlais - Pasadena CA, US Philip Hammond - Sierra Madre CA, US David Carmichael - Monrovia CA, US Bao-lu Chen - San Ramon CA, US Seung Chu - Upland CA, US Sher Karki - Ponoma CA, US
Assignee:
XENCOR, INC. - Monrovia CA
International Classification:
A61K 39/395 C07K 16/28
US Classification:
424144100, 530388220
Abstract:
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcγR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
Gregory Lazar - Arcadia CA, US John Desjarlais - Pasadena CA, US Philip Hammond - Sierra Madre CA, US David Carmichael - Monrovia CA, US Bao-lu Chen - San Ramon CA, US Seung Chu - Upland CA, US Sher Karki - Ponoma CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
A61K 39/395 C07K 16/30
US Classification:
424144100, 530388220
Abstract:
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcγR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
Tnf-Alpha Variant Formulations For The Treatment Of Tnf-Alpha Related Disorders
John Desjarlais - Pasadena CA, US Sher Karki - Pasadena CA, US Gregory Lazar - Arcadia CA, US John Richards - Monrovia CA, US Gregory Moore - Pasadena CA, US David Carmichael - Monrovia CA, US
Assignee:
Xencor.Inc. - Monrovia CA
International Classification:
C12N 5/10 C07K 14/47 C07K 16/28
US Classification:
435325000, 530350000, 530387900
Abstract:
The present invention relates to Fc variants with optimized Fc receptor binding properties, methods for their generation, Fc polypeptides comprising Fc variants with optimized Fc receptor binding properties, and methods for using Fc variants with optimized Fc receptor binding properties.
Fc Variants With Optimized Fc Receptor Binding Properties
John R. Desjarlais - Pasadena CA, US Sher Bahadur Karki - Pasadena CA, US Gregory Alan Lazar - Arcadia CA, US John O. Richards - Monrovia CA, US Gregory L. Moore - Pasadena CA, US David F. Carmichael - Monrovia CA, US
International Classification:
C12N 5/00 C07K 16/00
US Classification:
435375, 5303871
Abstract:
The present invention relates to Fc variants with optimized Fc receptor binding properties, methods for their generation, Fc polypeptides comprising Fc variants with optimized Fc receptor binding properties, and methods for using Fc variants with optimized Fc receptor binding properties.
Sun Automation Group - 51152 since Mar 2013
Service Coordinator
MEGTEC Systems, Inc. Oct 2007 - Mar 2013
Digital Printing Service Coordinator
MEGTEC Systems, Inc. 2006 - 2009
Field Service Coordinator
Skills:
Digital Printing Manufacturing Project Management Process Improvement Offset Printing Customer Service Troubleshooting Strategic Planning Electricians Training Six Sigma Process Engineering
David is a retired schoiol administrator. He recently joined the Dalit Freedom Network Canada as their Western Canadian Regional Representative. DFN is an... David is a retired schoiol administrator. He recently joined the Dalit Freedom Network Canada as their Western Canadian Regional Representative. DFN is an organization that builds schools for the untouchables of India. He is pictured above with Dr Joseph D Souza, president of DFN India.
David Carmichael, a lawyer for Mr. Colon, did not immediately respond to requests for comment on Tuesday night. But he told The Tampa Bay Times that Mr. Colon had initially tried to bring the theft to the attention of the Polk County Fire Rescue chief, but the chief was out of town. That was when he
Married Since 1996 to Nicole with 6 great kids! Bradly, Jeffrey, Rebecca, Lizi, Faith and Ben. Truly Blessed!
Bragging Rights:
Graduated Bloomington High School South in 1980
Graduated Ivy Tech Associates Degree in Machine Tool
Management Success in Glendale, California
Founded Carmichael Truck & Automotive Service, Inc. in November of 2001
David Carmichael
Work:
WYCU Your Local View - Anchorman/Reporter/Editor/Prod... (2012)
Education:
Lyndon State College - Electronic Journalism Arts
David Carmichael
Education:
Chaparral
Tagline:
I live in my own world. It's OK. They know me here. Growing older is mandatory, Growing up is optional!