David L Goldman

US Patent:

7643909, Jan 5, 2010

Filed:

Mar 30, 2006

Appl. No.:

11/278071

Inventors:

David J. Goldman - North Andover MA, US
Martin Ryan - Reading MA, US
Vladislav Davidkovich - Stoneham MA, US
Gordon Hill - Arlington MA, US

Assignee:

MKS Instruments, Inc. - Wilmington MA

International Classification:

G06F 19/00

US Classification:

700282, 251 3005

Abstract:

A master valve and at least one slave valve are connected via a network, wherein upon broadcast of a position setpoint of the master valve the at least one slave valve achieves a corresponding position within a shortened period of time, such network being a dedicated network or high speed shared network with position setpoint priority.

US Patent:

20070254288, Nov 1, 2007

Filed:

Oct 20, 2006

Appl. No.:

11/584449

Inventors:

Clifford Woolf - Newton MA, US
Michael Costigan - Somerville MA, US
Mitchell Max - Garrett Park MD, US
Inna Belfer - Rockville MD, US
Steven Atlas - Cambridge MA, US
Albert Kingman - Bethesda MD, US
Tianxia Wu - Potomac MD, US
David Goldman - Potomac MD, US

Assignee:

The General Hospital Corporation - Boston MA
National Institutes of Health - Bethesda MD

International Classification:

C12Q 1/02
C12Q 1/68

US Classification:

435006000, 435029000

Abstract:

Disclosed herein are methods for determining whether a subject possesses altered pain sensitivity an altered risk of developing acute or chronic pain, or diagnosing a tetrahydrobiopterin (BH4)-related disorder or a propensity thereto. These methods are based on the discovery of GCH1 and KCNS1 allelic variants that are associated with altered pain sensitivity and altered risk of developing acute or chronic pain, and the discovery that a GCH1 “pain protective haplotype” is associated with decreased upregulation of BH4 synthesis in treated leukocytes.

US Patent:

20120097081, Apr 26, 2012

Filed:

Oct 25, 2010

Appl. No.:

12/911462

Inventors:

Anthony A. Breen - Walpole MA, US
David A. Goldman - Bedford MA, US
Kristen R. Frias - Haverhill MA, US

International Classification:

D05C 3/00

US Classification:

112 78

Abstract:

An embroidery workstation utility cart for optimizing the positioning of supports for the embroidery machine, thread spool rack, monitor, workpiece queue, and other accessories desired for optimal embroidery processing.

US Patent:

20120101790, Apr 26, 2012

Filed:

Oct 25, 2010

Appl. No.:

12/911521

Inventors:

Eugene Hsu - Somerville MA, US
David A. Goldman - Bedford MA, US

International Classification:

G06G 7/48

US Classification:

703 6

Abstract:

Rendering methods, systems, and computer-readable media for rendering a simulated embroidery design image based on an embroidery design are presented. Given an embroidery design comprising a plurality of stitch representations and a lighting angle for the simulated embroidery design image, embodiments process the stitch representations to determine a stitch length and lighting angle and select from a stitch image database a stitch image corresponding to the stitch length and lighting angle, and place the selected stitch on a rendering canvas in a position corresponding to the stitch position indicated by the stitch representation. When rendered, all of individual stitch image on the rendering canvas appear to be illuminated from the same direction.

US Patent:

20130166193, Jun 27, 2013

Filed:

Dec 22, 2011

Appl. No.:

13/335124

Inventors:

David Allan Goldman - Bedford MA, US
Nirav Balkrishna Patel - Waltham MA, US

International Classification:

G01C 21/12

US Classification:

701410, 701445

Abstract:

An indoor navigational system determines a location of a moveable object in an indoor area and displays this location to a user. The system includes one or more dead-reckoning sensors, one or more absolute position sensors, and a processor. The processor determines the location of the moveable object based on signals received from the sensors. The system also includes a display device to display the location of the moveable object in a graphical representation of the indoor area based on messages from the processor indicating the location of the moveable object.

US Patent:

20130216615, Aug 22, 2013

Filed:

Feb 6, 2013

Appl. No.:

13/760916

Inventors:

David Goldman - Medfield MA, US

International Classification:

A61K 31/225
A61K 45/06
A61K 31/60

US Classification:

424451, 424489, 424490, 514163, 514547

Abstract:

Provided herein are compositions containing compounds, or pharmaceutically acceptable salts, that metabolize to monomethyl fumarate with certain pharmacokinetic parameters and methods for treating, prophylaxis, or amelioration of neurodegenerative diseases including multiple sclerosis using such compositions in a subject, wherein if the compositions contain dimethyl fumarate, the total amount of dimethyl fumarate in the compositions ranges from about 43% w/w to about 95% w/w.

US Patent:

20130261964, Oct 3, 2013

Filed:

Mar 15, 2013

Appl. No.:

13/839512

Inventors:

David Allan Goldman - Bedford MA, US
Nirav Balkrishna Patel - Waltham MA, US

International Classification:

G01C 21/20
G01B 7/14

US Classification:

701500, 701408, 32420713, 32420712, 3242072

Abstract:

An indoor navigational system determines a location of a moveable object in an indoor area and displays this location to a user. The system includes an absolute position sensor coupled to a case attached to a moveable object including a motion sensor coupled to a case including a first magnetic field sensor configured to detect a polarity of a magnet as the magnet passes in proximity to the first magnetic field sensor, a code wheel having two or more magnets alternately oriented with north and south polarities facing toward the first magnetic sensor, the code wheel positioned to rotate in unison with a wheel of the moveable object, and encoder circuitry configured to determine an amount of rotation of the wheel of the moveable object based on an output of the first magnetic field sensor.

US Patent:

51016460, Apr 7, 1992

Filed:

Mar 7, 1991

Appl. No.:

7/666856

Inventors:

David S. Goldman - Hopkinton MA
Craig L. Krigsman - Bergenfield NJ

International Classification:

E05B 6722

US Classification:

70 38A

Abstract:

The invention provides a lock having a thick U-shaped shackle, a transverse housing for receivably locking extending ends of the shackle, a pair of longitudinal members which lockably intersect the shackle ends and which are actuated by a lock protected within the intermediate portion of the housing. In an exemplary embodiment of the invention, the shackle and housing are constructed of substantially thick tubular metal, and the shackle ends may be conformed to openings in the housing. The longitudinal members may be extended post members which intersect inserted shackle ends or may be forked members which slidably engage flat portions on inserted shackle ends. The locking mechanism may be activated through a rack-and-pinion, cam-and-pin, or similar assembly, and may further comprise shackle ends having flat sections conformed to the housing openings to prevent rotation. The compact and integral design affords improved resistance to tampering such as by shattering or cutting/twisting methods.