David Jeffrey Goldman

US Patent:

6762294, Jul 13, 2004

Filed:

Aug 15, 2001

Appl. No.:

09/930589

Inventors:

David Goldman - Potomac MD
Nakao Iwata - Aichi, JP
Marc A. Schuckit - Del Mar CA

Assignee:

The United States of America as represented by the Department of Health and Human Services - Washington DC

International Classification:

C07H 2104

US Classification:

536 235, 435 6

Abstract:

Compositions and methods based on a polymorphism in the gene encoding the 6 subunit of the human GABA neurotransmitter receptor are disclosed. This polymorphism results in the substitution of a serine residue for a proline residue ordinarily present at amino acid position 385 of the 6 polypeptide sequence. Significantly, the polymorphism was associated with decreased sensitivity to ethanol and benzodiazepine drugs.

US Patent:

7273699, Sep 25, 2007

Filed:

Jul 25, 2002

Appl. No.:

10/206561

Inventors:

Robert H. Lipsky - Kensington MD, US
Chiara Mazzanti - Washington DC, US
David Goldman - Potomac MD, US

Assignee:

The United States of America as Represented by the Secretary of the Department of Health and Human Services - Washington DC

International Classification:

C12Q 1/68
C12P 19/34

US Classification:

435 6, 435 912

Abstract:

Sequence variations, such as polymorphisms, are detected by detecting differences between or among melting profiles of plural nucleic acids. Melting profiles are produced by observing the nucleic acids during a temperature change over a period of time. If the nucleic acids are diluted into solutions for analysis, the nucleic acid concentrations between or among the solutions can be substantially the same. The melting profiles and sequence variation can be used to identify changes in a wild-type nucleic acid sequence, such as a single-nucleotide polymorphism (SNP), a small insertion or deletion, or a small inversion.

US Patent:

7582679, Sep 1, 2009

Filed:

Feb 3, 2006

Appl. No.:

11/346975

Inventors:

Emadeldin Hassan - Cockeysville MD, US
Sridhar Gumudavelli - Cockeysville MD, US
David Goldman - Glen Arm MD, US

Assignee:

Pharmaceutics International Incorporated - Hunt Valley MD

International Classification:

A61K 31/19

US Classification:

514570

Abstract:

The present invention is directed to a solid ibuprofen concentrate composition and method of producing the composition. The solid ibuprofen concentrate contains (a) a solid ibuprofen free acid and (b) a solid ibuprofen alkali salt, and is characterized in that at least 90% of the weight of the solid ibuprofen concentrate is ibuprofen free acid and ibuprofen alkali salt.

US Patent:

8006958, Aug 30, 2011

Filed:

Nov 15, 2007

Appl. No.:

11/985573

Inventors:

Shelby K. Starks - Baltimore MD, US
David A. Carrier - Aberdeen MD, US
Daniel J. White - Baltimore MD, US
Daniel N. Lopano - Towson MD, US
James B. Watson - Fallston MD, US
Lauren M. Wenchel - Bel Air MD, US
David A. Goldman - Phoenix MD, US
Maurice L. LaPointe - Ellicott City MD, US
Daniele C. Brotto - Baltimore MD, US
Gabriel E. Concari - Eldersburg MD, US
William J. Robinson - Ellicott City MD, US

Assignee:

Black & Decker Inc. - Newark DE

International Classification:

B66D 1/00

US Classification:

254323

Abstract:

A portable winch assembly includes a winch mechanism connected to a support structure adapted to be manually transportable. A battery pack is releasably coupled to a remote control unit. The remote control unit is operated to control the winch mechanism. The battery pack and the remote control unit can be electrically connected to the winch mechanism by a flexible power cable, or the battery pack can be mounted with the winch mechanism and a wireless remote control unit can be used to operate the winch mechanism.

US Patent:

8578621, Nov 12, 2013

Filed:

Jun 24, 2010

Appl. No.:

12/822989

Inventors:

Sarah Jane Montplaisir - Joppa MD, US
David Andrew Goldman - Phoenix MD, US

Assignee:

Chang Type Industrial Company, Ltd. - Taichung County

International Classification:

G01B 11/27

US Classification:

33638, 33286, 33DIG 21

Abstract:

A laser alignment system for a drill press includes first and second adjustable laser assemblies mountable on the drill press. Each adjustable laser assembly includes a base firmly affixed to the drill press, a rotatable element mounted on the base and being adapted to selectively rotate relative to the base, a pivotable element mounted on the rotatable element and being adapted to selectively pivot relative to the rotatable element, and a laser mounted on the pivotable element and being adapted to move simultaneously with the pivotable element. The laser alignment system includes a pivot adjusting mechanism coupled with the pivotable element for selectively pivoting the pivotable element relative to the rotatable element, and a rotation adjusting mechanism coupled with the rotatable element for selectively rotating the rotatable element relative to the base.

US Patent:

8635571, Jan 21, 2014

Filed:

Oct 19, 2012

Appl. No.:

13/656361

Inventors:

David Samuel Goldman - Washington DC, US

Assignee:

Altera Corporation - San Jose CA

International Classification:

G06F 17/50

US Classification:

716117, 716116

Abstract:

This disclosure relates generally to field-programmable gate arrays (FPGAs). Some implementations relate to methods and systems for transmitting and integrating an intellectual property (IP) block with another user's design. The IP developer can design the IP block to include both a secret portion and a public portion. The IP block developer can send or otherwise provide the IP block to another IP user without disclosing the functional description of the secret portion of the IP block. In some implementations, the IP developer provides the public portion to the IP user at the register-transfer-level (RTL) level, as a hardware description language (HDL)-implemented design, or as a synthesizable netlist. In some implementations, the IP developer provides the secret portion of the IP block to the user in the form of programming bits without providing an HDL, RTL, or netlist implementation of the secret portion.

US Patent:

20030100476, May 29, 2003

Filed:

May 10, 2002

Appl. No.:

10/144000

Inventors:

Daniel Weinberger - Washington DC, US
Michael Egan - Chevy Chase MD, US
Terry Goldberg - Bethesda MD, US
Joseph Callicott - Bethesda MD, US
David Goldman - Potomac MD, US

International Classification:

A61K031/00
C12Q001/68

US Classification:

514/001000, 435/006000

Abstract:

The invention provides a method of detecting impaired prefrontal cognitive function in an individual by determining the individual's COMT genotype, and associating a high activity Val allele with impaired prefrontal cognitive function (and a low activity Met allele with enhanced prefrontal cognitive function).

US Patent:

20050014170, Jan 20, 2005

Filed:

Feb 27, 2004

Appl. No.:

10/789169

Inventors:

Daniel Weinberger - Washington DC, US
Michael Egan - Chevy Chase MD, US
Bhaskar Kolachana - Oakton VA, US
David Goldman - Potomac MD, US
Joseph Callicott - Bethesda MD, US
Terry Goldberg - Bethesda MD, US

International Classification:

C12Q001/68

US Classification:

435006000

Abstract:

The invention is related to the discovery that a met66val polymorphism in the gene for brain-derived neurotrophic factor (BDNF) is correlated with hippocampal function and verbal memory and risk for neuropsychiatric disorders such as schizophrenia.