David M Shepard

US Patent:

7162008, Jan 9, 2007

Filed:

Dec 3, 2002

Appl. No.:

10/308090

Inventors:

Matt A. Earl - Columbia MD, US
David M. Shepard - Severn MD, US
Xinsheng Yu - Clarksville MD, US

Assignee:

University of Maryland, Baltimore - Baltimore MD

International Classification:

A61N 5/10

US Classification:

378 65, 378149, 378151, 378152

Abstract:

A new optimization method for generating treatment plans for radiation oncology is described and claimed. This new method works for intensity modulated radiation therapy (IMRT), intensity modulated arc therapy (IMAT), and hybrid IMRT.

US Patent:

7333591, Feb 19, 2008

Filed:

Oct 27, 2006

Appl. No.:

11/588294

Inventors:

Matt A. Earl - Columbia MD, US
David M. Shepard - Severn MD, US
Xinsheng Yu - Clarksville MD, US

Assignee:

University of Maryland, Baltimore - Baltimore MD

International Classification:

A61N 5/10

US Classification:

378 65, 378149, 378151, 378152

Abstract:

A new optimization method for generating treatment plans for radiation oncology is described and claimed. This new method works for intensity modulated radiation therapy (IMRT), intensity modulated arc therapy (IMAT), and hybrid IMRT.

US Patent:

7875057, Jan 25, 2011

Filed:

Jan 22, 2008

Appl. No.:

12/010184

Inventors:

James L. Cook - Columbia MO, US
David O. Shepard - Naples FL, US
Anthony Orozco - Woodstock GA, US

Assignee:

Arthrex, Inc. - Naples FL

International Classification:

A61B 17/04
A61B 17/84
A61F 2/08

US Classification:

606232, 606300, 623 1312, 128898

Abstract:

A method for stabilization of a cranial cruciate ligament in canines using a suture-button construct. The method includes the steps of drilling a hole across the femur and the tibia, passing a needle with a pull-through suture strand through the femoral hole, and applying a tensile force to the pull-through suture strand and a suture tape such that a first button lies sideways for passage through the femoral hole, advancing the first button through the femoral hole until the first button exits the femoral hole, passing the needle with the pull-through suture strand through the tibial hole, applying a tensile force to the pull-through suture strand and the suture tape such that the first button lies sideways for passage through the tibial hole, flipping the first button to engage it against the tibia, pulling free ends of the suture tape to advance a second button and to seat and secure it against the femur.

US Patent:

7998206, Aug 16, 2011

Filed:

Mar 8, 2006

Appl. No.:

11/369962

Inventors:

David O. Shepard - Naples FL, US

Assignee:

Arthrex, Inc. - Naples FL

International Classification:

A61F 2/28
A61L 2/00

US Classification:

623 1611, 422 28, 422532

Abstract:

An osteochondral centrifugation system for providing an osteochondral centrifuged core from a graft such as femoral condyle, for example. The centrifugation system may be used either in the operating room or, alternatively, at a tissue banking facility at the time of processing. The osteochondral centrifuged core is formed by (i) removing an osteochondral core from a graft; (ii) placing the osteochondral core in a centrifugation system to remove blood, lipids, or other potentially antigenic or contaminating materials, and to obtain a centrifuged core; and (iii) optionally, subjecting the centrifuged core to a material that reduces the chance of disease transmission and aids in the healing of the recipient site to which the centrifuged core is to be transferred.

US Patent:

8202298, Jun 19, 2012

Filed:

Jan 24, 2011

Appl. No.:

13/012031

Inventors:

James L. Cook - Columbia MO, US
David O. Shepard - Naples FL, US
Anthony Orozco - Woodstock GA, US

Assignee:

Arthrex, Inc. - Naples FL

International Classification:

A61B 17/04
A61B 17/84
A61F 2/08

US Classification:

606232, 606300, 623 1312, 128898

Abstract:

An apparatus and method for stabilization of a cranial cruciate ligament deficient stifle in canines using a suture-button construct. The method includes the steps of drilling a femoral hole across a distal femur, passing a needle with a pull-through suture strand of a suture-button construct through the femoral hole, and applying a tensile force to the pull-through suture strand and a suture tape or strand of the construct such that a first button of the suture-button construct lies sideways for passage through the femoral hole, advancing the first button through the femoral hole by pulling the pull-through suture strand until the first button exits the femoral hole, drilling a tibial hole and passing the needle with the pull-through suture strand through the tibial hole, applying a tensile force to the pull-through suture strand and the suture tape or strand of the construct such that the first button lies sideways for passage through the tibial hole, flipping the first button to engage the first button against the medial tibial cortex and subsequently cutting and removing the pull-through suture strand, pulling free ends of the suture tape or strand to advance a second button of the suture-button construct and to seat the second button against the femur, and securing the second button against the femur.

US Patent:

8460227, Jun 11, 2013

Filed:

Nov 10, 2009

Appl. No.:

12/616081

Inventors:

Christopher Bare - Naples FL, US
David O. Shepard - Naples FL, US

Assignee:

Arthrex, Inc. - Naples FL

International Classification:

A61M 37/00
A61B 19/00

US Classification:

604 615, 604403

Abstract:

Apparatus and methods for producing interleukin-1 receptor antagonist and/or other prophylatically or therapeutically effective protein. Blood is obtained from a patient with a conventional syringe and then introduced into dual luer lock centrifuge tube. The dual luer lock centrifuge tube is provided with beads that are coated with a silanized coating. The container is then incubated and centrifuged. Subsequent to the incubation and the centrifugation, the serum containing autologous therapeutically active protein, such as IL-1Ra, in the container is withdrawn through the luer lock of the container, and injected back into the patient.

US Patent:

8465521, Jun 18, 2013

Filed:

Oct 12, 2006

Appl. No.:

11/546391

Inventors:

James L. Cook - Columbia MO, US
David O. Shepard - Naples FL, US
Matthew C. Summitt - Naples FL, US

Assignee:

Arthrex, Inc. - Naples FL

International Classification:

A61B 17/04
A61B 17/06

US Classification:

606228, 606223

Abstract:

A suture needle construct and method for extracapsular ligament reconstruction in mammals. The joint is first is first explored, and the damaged ligament and meniscus are debrided. The joint capsule is closed and a tunnel is created at the appropriate location in the proximal tibia for tibial fixation. Subsequent to the formation of the tibial tunnel, a suture having a substantially curved needle at one end and a substantially straight needle at the other end is brought in the proximity of the joint. The suture is passed around the lateral fabella using the substantially curved needle, then deep to the patellar ligament using the substantially straight needle, and through the tibial tunnel using the straight needle. The needles are cut off, and the sutures are tensioned over repair site.

US Patent:

20060177515, Aug 10, 2006

Filed:

Feb 9, 2006

Appl. No.:

11/350078

Inventors:

Reinhold Schmieding - Naples FL, US
David Shepard - Naples FL, US

International Classification:

A61K 35/16

US Classification:

424531000

Abstract:

A method of producing blood serum containing prophylactically or therapeutically active proteins, including obtaining blood from a patient, incubating the blood at a suitable temperature to induce production of prophylactically or therapeutically active proteins, and removing the prophylactically or therapeutically active proteins from the blood.