David M Shepard

US Patent:

7998206, Aug 16, 2011

Filed:

Mar 8, 2006

Appl. No.:

11/369962

Inventors:

David O. Shepard - Naples FL, US

Assignee:

Arthrex, Inc. - Naples FL

International Classification:

A61F 2/28
A61L 2/00

US Classification:

623 1611, 422 28, 422532

Abstract:

An osteochondral centrifugation system for providing an osteochondral centrifuged core from a graft such as femoral condyle, for example. The centrifugation system may be used either in the operating room or, alternatively, at a tissue banking facility at the time of processing. The osteochondral centrifuged core is formed by (i) removing an osteochondral core from a graft; (ii) placing the osteochondral core in a centrifugation system to remove blood, lipids, or other potentially antigenic or contaminating materials, and to obtain a centrifuged core; and (iii) optionally, subjecting the centrifuged core to a material that reduces the chance of disease transmission and aids in the healing of the recipient site to which the centrifuged core is to be transferred.

US Patent:

8460227, Jun 11, 2013

Filed:

Nov 10, 2009

Appl. No.:

12/616081

Inventors:

Christopher Bare - Naples FL, US
David O. Shepard - Naples FL, US

Assignee:

Arthrex, Inc. - Naples FL

International Classification:

A61M 37/00
A61B 19/00

US Classification:

604 615, 604403

Abstract:

Apparatus and methods for producing interleukin-1 receptor antagonist and/or other prophylatically or therapeutically effective protein. Blood is obtained from a patient with a conventional syringe and then introduced into dual luer lock centrifuge tube. The dual luer lock centrifuge tube is provided with beads that are coated with a silanized coating. The container is then incubated and centrifuged. Subsequent to the incubation and the centrifugation, the serum containing autologous therapeutically active protein, such as IL-1Ra, in the container is withdrawn through the luer lock of the container, and injected back into the patient.

US Patent:

20060177515, Aug 10, 2006

Filed:

Feb 9, 2006

Appl. No.:

11/350078

Inventors:

Reinhold Schmieding - Naples FL, US
David Shepard - Naples FL, US

International Classification:

A61K 35/16

US Classification:

424531000

Abstract:

A method of producing blood serum containing prophylactically or therapeutically active proteins, including obtaining blood from a patient, incubating the blood at a suitable temperature to induce production of prophylactically or therapeutically active proteins, and removing the prophylactically or therapeutically active proteins from the blood.

US Patent:

20120264699, Oct 18, 2012

Filed:

Jun 25, 2012

Appl. No.:

13/532178

Inventors:

Reinhold Schmieding - Naples FL, US
David O. Shepard - Naples FL, US

International Classification:

A61K 38/02

US Classification:

514 2192

Abstract:

A method of producing blood serum containing prophylactically or therapeutically active proteins, including obtaining blood from a patient, incubating the blood at a suitable temperature to induce production of prophylactically or therapeutically active proteins, and removing the prophylactically or therapeutically active proteins from the blood.

US Patent:

20130338792, Dec 19, 2013

Filed:

Jun 6, 2013

Appl. No.:

13/911135

Inventors:

Brandon L. Roller - Naples FL, US
David O. Shepard - Naples FL, US
G. Joshua Karnes - Estero FL, US
Robert Benedict - Fort Myers FL, US
Tithi Dutta Roy - Estero FL, US
Brian J. Cole - Chicago IL, US
James P. Bradley - Pittsburgh PA, US
Eric Giza - Carmichael CA, US
James L. Cook - Columbia MO, US
Lisa A. Fortier - Syracuse NY, US

International Classification:

A61F 2/30

US Classification:

623 2373

Abstract:

Techniques, mixtures, mixing and delivery kits, and improved delivery instruments for implantation of micronized allograft tissue over a microfractured defect. Allograft cartilage tissue is delivered over a cartilage defect that has been debrided and microfractured, without the need for a periosteal covering or separate type of patch sewn over the top. The allograft tissue may be any micronized cartilage particulates obtained by various methods, for example, cartilage delivered in its native form, dehydrated via lyophilization, “freeze-dried,” dehydrated via desiccation, or dehydrated by any other method.

US Patent:

20180055622, Mar 1, 2018

Filed:

Aug 23, 2017

Appl. No.:

15/683868

Inventors:

- Naples FL, US
David Shepard - Naples FL, US
Brian Dorn - Naples FL, US

International Classification:

A61F 2/08
A61L 27/58
A61L 27/54
A61L 27/38
A61L 27/36

Abstract:

The present disclosure describes methods of treating an injury in a subject using placental tissue streamers, engineered tissue placental tissue hybrids, suture placental tissue hybrids, placental tissue patch hybrids, and tissue hybrids, and the use of these compositions to repair, treat, or support an injury or degenerative process in a subject.

US Patent:

20170215894, Aug 3, 2017

Filed:

Jan 31, 2017

Appl. No.:

15/420338

Inventors:

- Naples FL, US
John M. Konicek - Naples FL, US
David O. Shepard - Naples FL, US
Brandon L. Roller - Naples FL, US

International Classification:

A61B 17/16
A61B 17/92
A61B 17/15
A61B 17/17
A61F 2/46
A61F 2/30

Abstract:

A technique for knee replacement surgery that allow for the removal of an oval oblong-shaped allograft bone and cartilage plug from a donor distal femur. The technique uses instruments including (i) sizing guides to match the recipient's femoral size and curvature to that of a donor femur (the sizing guides also acting as a wide pin placement template for the donor distal femur); (ii) osteotomes that cut the curved and straight portions of the implant shape (these may be disposable or reusable); and (iii) templates that fit over the guide pins and have openings to allow the osteotomes to cut the donor femur plug to the correct size, shape and depth. The instruments allow for a non-circular shape to be extracted from a donor femur for use in a bone-saving osteoarthritis distal femur resurfacing procedure.

US Patent:

20160199549, Jul 14, 2016

Filed:

Jan 8, 2015

Appl. No.:

14/591955

Inventors:

- Naples FL, US
Brandon ROLLER - Naples FL, US
James R. McWILLIAM - Rye NY, US
Frank GRIMALDI, JR. - Naples FL, US
David SHEPARD - Naples FL, US

International Classification:

A61M 1/00
A61F 13/38
A61M 27/00

Abstract:

A surgical method according to an exemplary aspect of the present disclosure includes, among other things, drying an osteochondral defect using a suction swab. The drying step includes suctioning moisture from the osteochondral defect through the suction swab or communicating a gas to the osteochondral defect through the suction swab.