Robert Taylor - Lansdale PA, US Dianne Rothstein - Ambler PA, US
Assignee:
Severn Trent Water Purification Inc. - Colmar PA
International Classification:
G01N033/00
US Classification:
436/125000
Abstract:
Methods of measuring free and total chlorine content in solutions are provided without lowering the pH of the solution to the acid range by modifying a solution containing chlorine and water to contain a proton donating compound and electrochemically measuring the concentration of the chlorine in the solution. An additional potassium iodide reagent is added when total chlorine content is measured. Stable aqueous reagent solutions useful in automated chlorine analyzers which contain sodium bicarbonate, a base, and water or borax, water, and acid are also described. Finally, apparatuses for detecting the level of chlorine in water samples utilizing an automated chlorine detector, a cartridge having a solid proton donating compound, and optionally a standpipe are discussed.
Hybrid Solid Supports Useful For Oligonucleotide Production
MARC L. ROTHSTEIN - Ambler PA, US Dianne M. Rothstein - Ambler PA, US Dan P. Lee - Reno NV, US
Assignee:
Prime Synthesis, Inc. - Aston PA
International Classification:
C07K 1/04 C07H 21/00 B05D 7/00 B32B 5/16
US Classification:
530334, 536 253, 427221, 428406
Abstract:
A method for preparing a crosslinked polymer coated controlled porosity glass (CPG) particle is provided. The method involves mixing CPG particles in a solution comprising polyvinylbenzylchloride and a first solvent at a temperature below 10 C. A second solvent is added and a crosslinking agent is added to the mixture. The first solvent is removed rapidly within 1 hours of addition of the crosslinking agent. The crosslinking reaction is permitted to proceed and the mixture is then cooled and treated to remove any remaining solvent. The resulting coated CPG particles are washed and dried. Also provided a polymer coated CPG particles using for loading ligand thereon.
Hybrid Solid Supports Useful For Oligonucleotide Production
- Aston PA, US Dianne M. Rothstein - Ambler PA, US Dan P. Lee - Reno NV, US
International Classification:
C07H 21/00
US Classification:
536 253, 427212
Abstract:
A method for preparing a crosslinked polymer coated controlled porosity glass (CPG) particle is provided. The method involves mixing CPG particles in a solution comprising polyvinylbenzylchloride and a first solvent at a temperature below 10 C. A second solvent is added and a crosslinking agent is added to the mixture. The first solvent is removed rapidly within hours of addition of the crosslinking agent. The crosslinking reaction is permitted to proceed and the mixture is then cooled and treated to remove any remaining solvent. The resulting coated CPG particles are washed and dried. Also provided a polymer coated CPG particles using for loading ligand thereon.
Hybrid Solid Supports Useful For Oligonucleotide Production
- Aston PA, US Dianne M. Rothstein - Ambler PA, US Dan P. Lee - Reno NV, US
Assignee:
Prime Synthesis, Inc. - Aston PA
International Classification:
C07H 21/00
US Classification:
428406, 536 253, 427212
Abstract:
A method for preparing a crosslinked polymer coated controlled porosity glass (CPG) particle is provided. The method involves mixing CPG particles in a solution comprising polyvinylbenzylchloride and a first solvent at a temperature below 10 C. A second solvent is added and a crosslinking agent is added to the mixture. The first solvent is removed rapidly within 1 hours of addition of the crosslinking agent. The crosslinking reaction is permitted to proceed and the mixture is then cooled and treated to remove any remaining solvent. The resulting coated CPG particles are washed and dried. Also provided a polymer coated CPG particles using for loading ligand thereon.
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