Eddie O Adams

US Patent:

20210317434, Oct 14, 2021

Filed:

Nov 20, 2020

Appl. No.:

16/953857

Inventors:

- Germantown MD, US
Eddie ADAMS - San Diego CA, US
Mark BROLASKI - Encinitas CA, US
Ingemar PEDRON - San Diego CA, US

International Classification:

C12N 15/10

Abstract:

Provided are methods and compositions for negatively and positively selecting for different size nucleic acid (e.g., DNA or RNA) fragments on borosilicate glass fiber membranes, silica and metal oxide surfaces such that only those fragments falling within a desired size range are obtained.

US Patent:

20210290575, Sep 23, 2021

Filed:

Apr 6, 2021

Appl. No.:

17/223622

Inventors:

- San Diego CA, US
Eddie Adams - San Diego CA, US

International Classification:

A61K 31/20
A61K 9/00
A61K 31/015
A61K 31/03
A61K 31/11

Abstract:

Provided, in part, are methods, compositions, and systems are provided for detecting one or more repellent-generating enzymatic pathways by characterizing the skin microbiomes and metabolomes of populations of individuals both naturally resistant and highly prone to bites from blood sucking arthropods, determining the microbial taxa (and their associated metabolic pathways) most associated with insect repellency and targeting/activating those pathways with molecular substrates that, when metabolized, will give rise, in situ, to repellent molecules and can promote a shift to a more naturally repellent microbiome composition.

US Patent:

20210246160, Aug 12, 2021

Filed:

Apr 17, 2019

Appl. No.:

17/049748

Inventors:

- Germantown MD, US
Eddie W. ADAMS - San Diego CA, US

International Classification:

C07K 1/16
C07K 1/30

Abstract:

The present disclosure provides methods for isolating proteins and optionally nucleic acids from a sample, comprising: (a) contacting a sample, a lysate of the sample, a supernatant of the lysate, or a portion of the sample, the lysate or the supernatant with one or more first agents selected from low molecular weight carboxylates and sulfate and one or more second agents that are multivalent (e.g., trivalent) salt(s) to generate a mixture, (b) separating the mixture of step (a) into a solid phase and a liquid phase, wherein the one or more second agents are primarily in the solid phase, and (c) isolating proteins and optionally nucleic acids from the liquid phase of step (b). Compositions and kits useful in such methods are also disclosed.

US Patent:

20200397732, Dec 24, 2020

Filed:

Dec 4, 2018

Appl. No.:

16/769437

Inventors:

- San Diego CA, US
Eddie Adams - San Diego CA, US

International Classification:

A61K 31/20
A61K 9/00
A61K 31/03
A61K 31/11
A61K 31/015

Abstract:

Provided, in part, are methods, compositions, and systems are provided for detecting one or more repellent-generating enzymatic pathways by characterizing the skin microbiomes and metabolomes of populations of individuals both naturally resistant and highly prone to bites from blood sucking arthropods, determining the microbial taxa (and their associated metabolic pathways) most associated with insect repellency and targeting/activating those pathways with molecular substrates that, when metabolized, will give rise, in situ, to repellent molecules and can promote a shift to a more naturally repellent microbiome composition.

US Patent:

20190071665, Mar 7, 2019

Filed:

Sep 2, 2016

Appl. No.:

15/757330

Inventors:

- Germantown MD, US
Eddie ADAMS - San Diego CA, US
Mark N. BROLASKI - Encinitas CA, US
Victoria NIECIECKI - Vista CA, US

Assignee:

Qiagen Sciences LLC - Germantown MD

International Classification:

C12N 15/10
G01N 30/88

Abstract:

Provided are methods for isolating biomolecules, such as nucleic acids and proteins, from a sample using a silica-containing surface and/or a high salt, low pH buffer.

US Patent:

20180245064, Aug 30, 2018

Filed:

Sep 2, 2016

Appl. No.:

15/757323

Inventors:

- Germantown MD, US
Eddie ADAMS - San Diego CA, US
Mark N. BROLASKI - Encinitas CA, US
Ingemar PEDRON - San Diego CA, US

Assignee:

Qiagen Sciences LLC - Germantown MD

International Classification:

C12N 15/10

Abstract:

Provided are methods and compositions for negatively and positively selecting for different size nucleic acid (e.g., DNA or RNA) fragments on borosilicate glass fiber membranes, silica and metal oxide surfaces such that only those fragments falling within a desired size range are obtained.