Edward J Dempsey

US Patent:

20120085642, Apr 12, 2012

Filed:

May 16, 2011

Appl. No.:

13/108960

Inventors:

Devin Karns - Seattle WA, US
Jonathan Meuser - Golden CO, US
Matthew Posewitz - Golden CO, US
Edward Dempsey - Littleton CO, US

Assignee:

COLORADO SCHOOL OF MINES - Golden CO

International Classification:

G01N 33/50

US Classification:

20440301

Abstract:

A system for measuring hydrogen (H) and oxygen (O) including a sample system, a signal processing and system control device, at least one polarograph device and a computing device equipped with software for environmental and biological data analysis incorporating both user-defined and environmental data acquired by the signal processing and system control device. The system measures gas level or exchange (production and/or consumption) in the field or laboratory. In some embodiments, the system uses two Clark-type polarograph devices oppositely polarized with gas-specific polarographic circuits, wherein one polarograph device measures Hgas and the other measures Ogas. In some embodiments, the sample system includes an environmentally-controlled sample housing for accepting the polarograph devices and holding a test sample in a reservoir. The system measures Hor Oexchange in microbial samples, including microbial phototrophs which couple light harvesting to Hand/or Oexchange.

US Patent:

20120121573, May 17, 2012

Filed:

Sep 1, 2011

Appl. No.:

13/224126

Inventors:

Edward C. Dempsey - Aurora CO, US

International Classification:

A61K 38/48
A61P 11/00
A61P 9/00
A61P 9/12
G01N 33/573
C12Q 1/68
C12Q 1/37
A61K 48/00
A61P 29/00

US Classification:

424 9467, 514 44 R, 435 74, 435 613, 435 612, 435 23, 435 618

Abstract:

The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming from the inventor's discovery that Neprilysin is expressed at reduced levels in disease tissues.

US Patent:

39375056, Feb 10, 1976

Filed:

Mar 13, 1974

Appl. No.:

5/450825

Inventors:

Edward Dempsey - Bronx NY

Assignee:

Lawrence Peska Associates, Inc. - New York NY

International Classification:

E05C 330

US Classification:

292201

Abstract:

A hood locking device for vehicles for locking the hood over the engine compartment to prevent theft of the vehicle or of engine parts. It includes a main housing mountable inside the compartment by adjustable rods and brackets to fit most cars or trucks, there being an upper locking post securable to the hood and having a locking finger on its lower end which extends inside the main housing when the hood is lowered. The main housing has an elongated locking bar with an El shaped foot at its lower end, and being pivoted intermediate its ends. An electromagnet is energized from the car battery to swing the elongated locking bar for its upper end to engage with the locking finger to lock the hood. A modified form has the magnetic means energized to unlock the hood.

US Patent:

62288431, May 8, 2001

Filed:

Apr 21, 2000

Appl. No.:

9/557038

Inventors:

Edward C. Dempsey - Denver CO

Assignee:

University Technology Corporation - Boulder CO

International Classification:

A01N 4304

US Classification:

514 31

Abstract:

A method for treating pulmonary and systemic vascular diseases associated with cardiac hypotrophy, dysfunction or failure that involves the administration of an effective amount of a PKC antagonist to a patient suffering from one of such diseases is disclosed. PKC antagonists are selected from bryostatin derivatives and more preferably from bryostatin-1. The disease states treatable in accordance with the present invention are characterized by alterations in vascular structure, vascular tone, myocardial hypotrophy, dysfunction or failure, idiopathic pulmonary hypertension and chronic hypoxic pulmonary hypertension. Particular formulations include bryostatin-1 in an effective amount to treat one or more of the above-referenced diseases.

US Patent:

20150093373, Apr 2, 2015

Filed:

Oct 9, 2014

Appl. No.:

14/510738

Inventors:

- DENVER CO, US
Edward C. DEMPSEY - Aurora CO, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE - DENVER CO

International Classification:

A61K 38/48
C12N 9/64
C12Q 1/37
A61K 31/7088
G01N 33/573

US Classification:

424 9467, 514 44 R, 435 74, 435 618, 435 612, 435 23, 506 9, 435 611

Abstract:

The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming from the inventor's discovery that Neprilysin is expressed at reduced levels in disease tissues.