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Ernest Anthony Carra

age ~67

from Oxford, MA

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Also known as:
  • Ernest A Carra
  • Ernest Karra
Phone and address:
5 Water St, Oxford, MA 01540
(508)9875584
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Connected to:

Ernest Carra Phones & Addresses

  • 5 Water St, Oxford, MA 01540 • (508)9875584
  • 51 Mayher St, Springfield, MA 01104
  • Worcester, MA
  • Foster City, CA
  • South Hadley, MA
  • Boylston, MA
  • West Springfield, MA
  • 5 N Water St, Oxford, MA 01540

Us Patents

  • Crystalline Forms Of (3R, 3As, 6Ar) - Hexahydrofuro [2,3-B] Furan-3-Yl (1S,2R) - (1-{4-[ (Diethoxyphosphoryl) Methoxy] Pheny1}-3-Hydroxy-4- [4-Methoxy-N- (2-Methylpropyl) Benzenesul - Fonamido] Butan-2-Yl) Carbamate

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  • US Patent:
    20120232038, Sep 13, 2012
  • Filed:
    Jun 17, 2010
  • Appl. No.:
    13/378250
  • Inventors:
    Ernest Anthony Carra - Foster City CA, US
    Anna Chiu - Mountain View CA, US
    Jesper Alexis Jernelius - San Francisco CA, US
    Fang Wang - Foster City CA, US
  • Assignee:
    Gilead Sciences, Inc. - Foster City CA
  • International Classification:
    A61K 31/665
    A61P 31/18
    C07F 9/40
  • US Classification:
    514100, 549220
  • Abstract:
    The present inventions provides crystalline forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-(1-{4-[(diethoxyphosphoryl)methoxy]phenyl}-3-hydroxy-4-[4-methoxy-N-(2-methylpropyl)benzenesulfonamido]butan-2-yl)carbamate, methods of preparing the crystalline forms, pharmaceutical compositions containing the crystalline forms, and therapeutic uses thereof.

  • A1 Adenosine Receptor Agonist Polymorphs

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  • US Patent:
    20110039799, Feb 17, 2011
  • Filed:
    Aug 10, 2010
  • Appl. No.:
    12/854023
  • Inventors:
    Ernest Anthony Carra - Foster City CA, US
    Benjamin R. Graetz - San Mateo CA, US
    DeMei Leung - Los Altos CA, US
    Janaki Nyshadham - Fremont CA, US
    Robert Seemayer - Belmont CA, US
    Simon Kwok-Pan Yau - Sunnyvale CA, US
  • Assignee:
    Gilead Palo Alto, Inc. - Foster City CA
  • International Classification:
    A61K 31/7076
    C07H 19/167
    A61P 9/00
    A61P 3/10
    A61P 9/10
    A61P 3/04
    A61P 25/08
    A61P 3/00
  • US Classification:
    514 46, 536 273
  • Abstract:
    Provided are polymorphs of an Aadenosine receptor partial agonist, compositions thereof, methods for their preparation, and methods for their uses.

  • Crystalline Forms Of (S)-2-Ethylbutyl 2-(((S)-(((2R,3S,4R,5R)-5- (4-Aminopyrrolo[2,1-F] [1,2,4]Triazin-7-Yl)-5-Cyano-3,4-Dihydroxytetrahydrofuran-2-Yl)Methoxy) (Phenoxy) Phosphoryl)Amino)Propanoate

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  • US Patent:
    20210163523, Jun 3, 2021
  • Filed:
    Oct 13, 2020
  • Appl. No.:
    17/069248
  • Inventors:
    - Foster City CA, US
    Ernest A. Carra - Foster City CA, US
    Lars V. Heumann - Redwood City CA, US
    Nate Larson - Saint George UT, US
  • International Classification:
    C07H 19/00
    A61P 31/14
    C07F 9/6561
  • Abstract:
    The present invention relates to novel salts and crystalline forms of (S)-2-ethylbutyl 2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate for use in treating viral infections. In some embodiments, the viral infection is caused by a virus selected from the group consisting of Arenaviridae, Coronaviridae, Filoviridae, Flaviviridae, and Paramyxoviridae.

  • Solid Forms Of An Ask1 Inhibitor

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  • US Patent:
    20200061042, Feb 27, 2020
  • Filed:
    Aug 2, 2019
  • Appl. No.:
    16/530205
  • Inventors:
    - Foster City CA, US
    Brenda J. Burke Chan - Foster City CA, US
    Ernest A. Carra - Foster City CA, US
    Anna Chiu - Mountain View CA, US
    Olga Viktorovna Lapina - Newark CA, US
    Stephen P. Lathrop - Lake Bluff IL, US
    Gregory Notte - Redwood City CA, US
    Valeriya Smolenskaya - West Lafayette IN, US
    Lok Him Yu - Sacramento CA, US
  • International Classification:
    A61K 31/4439
    C07C 309/04
    C07C 59/06
    C07C 57/15
    C07C 57/145
    C07C 55/07
    A61K 31/541
    A61K 31/422
    C07D 401/14
    C07D 413/12
  • Abstract:
    Crystalline forms of 5-(4-cyclopropyl-1H-imidazol-1-yl)-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-2-fluoro-4-methylbenzamide (Compound I) were prepared and characterized in the solid state:Also provided are processes of manufacture and methods of using the crystalline forms.

  • Crystalline Forms Of (S)-2-Ethylbutyl 2-(((S)-(((2R,3S,4R,5R)-5- (4-Aminopyrrolo[2,1-F] [1,2,4]Triazin-7-Yl)-5-Cyano-3,4-Dihydroxytetrahydrofuran-2-Yl)Methoxy) (Phenoxy) Phosphoryl)Amino)Propanoate

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  • US Patent:
    20180346504, Dec 6, 2018
  • Filed:
    Apr 27, 2018
  • Appl. No.:
    15/964597
  • Inventors:
    - Foster City CA, US
    Ernest A. Carra - Foster City CA, US
    Lars V. Heumann - Redwood City CA, US
    Nate Larson - Saint George UT, US
  • International Classification:
    C07H 19/00
    A61P 31/14
  • Abstract:
    The present invention relates to novel salts and crystalline forms of (S)-2-ethylbutyl 2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate for use in treating viral infections. In some embodiments, the viral infection is caused by a virus selected from the group consisting of Arenaviridae, Coronaviridae, Filoviridae, Flaviviridae, and Paramyxoviridae.

  • Polymorphic Forms Of A Hydrochloride Salt Of (S)-2-(1-(9H-Purin-6-Ylamino)Propyl)-5-Fluoro-3-Phenylquinazolin-4(3H)-One

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  • US Patent:
    20180009811, Jan 11, 2018
  • Filed:
    Jun 16, 2017
  • Appl. No.:
    15/626048
  • Inventors:
    - Foster City CA, US
    Ernest CARRA - Foster City CA, US
    Tracy EHIWE - Cambridge, GB
    Duong TRAN - Edmonton, CA
    Fang WANG - Foster City CA, US
    Christopher WORRALL - Cambridge, GB
    Jerry Evarts - Seattle WA, US
  • International Classification:
    C07D 473/34
  • Abstract:
    Polymorphs of a hydrochloride salt of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one, compositions thereof, methods for their preparation, and methods for their use are disclosed. Solvent forms of a hydrochloride salt of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one, compositions thereof, methods for their preparation, and methods for their use are also disclosed.

  • (N-(Cyanomethyl)-4-(2-(4-Morpholinophenylamino)Pyrimidin-4-Yl)Benzamide

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  • US Patent:
    20160347719, Dec 1, 2016
  • Filed:
    Aug 8, 2016
  • Appl. No.:
    15/231411
  • Inventors:
    - Foster City CA, US
    Ernest A. Carra - Foster City CA, US
    Jeffrey N. Hemenway - San Mateo CA, US
    Henry Morrison - Dublin CA, US
    Troy Reynolds - San Francisco CA, US
    Bing Shi - Redwood City CA, US
    Dimitrios Stefanidis - Mountain View CA, US
    Fang Wang - Foster City CA, US
    Matthew Robert Warr - Madison CT, US
    James Andrew Whitney - Guilford CT, US
    Yan Xin - San Carlos CA, US
  • International Classification:
    C07D 239/42
  • Abstract:
    The present invention relates to stable novel salt forms of N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide that are suitable for the preparation of pharmaceutical formulations thereof, and their therapeutic use.

  • Solid Forms Of An Ask1 Inhibitor

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  • US Patent:
    20160280683, Sep 29, 2016
  • Filed:
    Dec 22, 2015
  • Appl. No.:
    14/757585
  • Inventors:
    - Foster City CA, US
    Brenda J. Burke Chan - Foster City CA, US
    Ernest A. Carra - Foster City CA, US
    Anna Chiu - Burlingame CA, US
    Olga Viktorovna Lapina - Foster City CA, US
    Stephen P. Lathrop - San Mateo CA, US
    Valeriya Smolenskaya - West Lafayette IN, US
    Lok Him Yu - Sacramento CA, US
  • Assignee:
    Gilead Sciences, Inc. - Foster City CA
  • International Classification:
    C07D 401/14
    C07C 57/15
    C07C 59/06
    A61K 31/422
    C07C 55/07
    A61K 31/4439
    A61K 31/541
    C07C 309/04
    C07C 57/145
  • Abstract:
    Crystalline forms of 5-(4-cyclopropyl-1H-imidazol-1-yl)-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-2-fluoro-4-methylbenzamide (Compound I) were prepared and characterized in the solid state:Also provided are processes of manufacture and methods of using the crystalline forms.
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